(10 nodes) Retrograde neurotrophin signalling, and Clathrin-dependent synaptic vesicle endocytosis network (Cottoperca gobio)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	clta	Clathrin light chain A. (232 aa)
	necap2	NECAP endocytosis associated 2. (255 aa)
	ap2s1	Adaptor related protein complex 2 subunit sigma 1. (156 aa)
	AP2M1	AP-2 complex subunit mu-A. (452 aa)
	ap2a1	Adaptor related protein complex 2 subunit alpha 1. (967 aa)
	LOC115017313	Clathrin heavy chain 1-like. (1684 aa)
	ap4b1	Adaptor related protein complex 4 subunit beta 1. (823 aa)
	LOC115018699	AP-1 complex subunit beta-1. (980 aa)
	LOC115020435	Intersectin-1-like. (1662 aa)
	itsn2	Intersectin 2. (1602 aa)

Your Current Organism:

Cottoperca gobio

NCBI taxonomy Id: 56716
Other names: Aphritis gobio, C. gobio

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AP2M1	LOC115017313	ENSCGOP00000026710	ENSCGOP00000033359	AP-2 complex subunit mu-A.	Clathrin heavy chain 1-like.	0.869
AP2M1	LOC115018699	ENSCGOP00000026710	ENSCGOP00000047988	AP-2 complex subunit mu-A.	AP-1 complex subunit beta-1.	0.983
AP2M1	LOC115020435	ENSCGOP00000026710	ENSCGOP00000049751	AP-2 complex subunit mu-A.	Intersectin-1-like.	0.997
AP2M1	ap2a1	ENSCGOP00000026710	ENSCGOP00000026724	AP-2 complex subunit mu-A.	Adaptor related protein complex 2 subunit alpha 1.	0.994
AP2M1	ap2s1	ENSCGOP00000026710	ENSCGOP00000017976	AP-2 complex subunit mu-A.	Adaptor related protein complex 2 subunit sigma 1.	0.992
AP2M1	ap4b1	ENSCGOP00000026710	ENSCGOP00000046140	AP-2 complex subunit mu-A.	Adaptor related protein complex 4 subunit beta 1.	0.966
AP2M1	clta	ENSCGOP00000026710	ENSCGOP00000000848	AP-2 complex subunit mu-A.	Clathrin light chain A.	0.908
AP2M1	itsn2	ENSCGOP00000026710	ENSCGOP00000055306	AP-2 complex subunit mu-A.	Intersectin 2.	0.999
AP2M1	necap2	ENSCGOP00000026710	ENSCGOP00000005138	AP-2 complex subunit mu-A.	NECAP endocytosis associated 2.	0.920
LOC115017313	AP2M1	ENSCGOP00000033359	ENSCGOP00000026710	Clathrin heavy chain 1-like.	AP-2 complex subunit mu-A.	0.869
LOC115017313	LOC115018699	ENSCGOP00000033359	ENSCGOP00000047988	Clathrin heavy chain 1-like.	AP-1 complex subunit beta-1.	0.968
LOC115017313	LOC115020435	ENSCGOP00000033359	ENSCGOP00000049751	Clathrin heavy chain 1-like.	Intersectin-1-like.	0.992
LOC115017313	ap2a1	ENSCGOP00000033359	ENSCGOP00000026724	Clathrin heavy chain 1-like.	Adaptor related protein complex 2 subunit alpha 1.	0.949
LOC115017313	ap2s1	ENSCGOP00000033359	ENSCGOP00000017976	Clathrin heavy chain 1-like.	Adaptor related protein complex 2 subunit sigma 1.	0.890
LOC115017313	ap4b1	ENSCGOP00000033359	ENSCGOP00000046140	Clathrin heavy chain 1-like.	Adaptor related protein complex 4 subunit beta 1.	0.927
LOC115017313	clta	ENSCGOP00000033359	ENSCGOP00000000848	Clathrin heavy chain 1-like.	Clathrin light chain A.	0.986
LOC115017313	itsn2	ENSCGOP00000033359	ENSCGOP00000055306	Clathrin heavy chain 1-like.	Intersectin 2.	0.994
LOC115017313	necap2	ENSCGOP00000033359	ENSCGOP00000005138	Clathrin heavy chain 1-like.	NECAP endocytosis associated 2.	0.676
LOC115018699	AP2M1	ENSCGOP00000047988	ENSCGOP00000026710	AP-1 complex subunit beta-1.	AP-2 complex subunit mu-A.	0.983
LOC115018699	LOC115017313	ENSCGOP00000047988	ENSCGOP00000033359	AP-1 complex subunit beta-1.	Clathrin heavy chain 1-like.	0.968