(16 nodes) TRAIL signaling, and Necroptotic process network (Labrus bergylta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	cflar	Uncharacterized protein; Belongs to the peptidase C14A family. (445 aa)
	LOC109981905	Uncharacterized protein. (315 aa)
	LOC109995799	Uncharacterized protein; Belongs to the peptidase C14A family. (489 aa)
	LOC109995961	Uncharacterized protein; Belongs to the peptidase C14A family. (369 aa)
	MLKL	Mixed lineage kinase domain like pseudokinase. (446 aa)
	LOC109982580	Fas ligand (TNF superfamily, member 6); Belongs to the tumor necrosis factor family. (266 aa)
	LOC109998157	Uncharacterized protein; Belongs to the protein kinase superfamily. (449 aa)
	LOC109975928	Uncharacterized protein; Belongs to the peptidase C14A family. (242 aa)
	LOC109975131	Uncharacterized protein. (303 aa)
	LOC109984320	Caspase 10, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (540 aa)
	LOC109994273	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (283 aa)
	fadd	Uncharacterized protein. (192 aa)
	LOC109998914	Tumor necrosis factor receptor superfamily, member a. (456 aa)
	LOC109995578	Receptor-interacting serine-threonine kinase 3. (494 aa)
	LOC109995177	Uncharacterized protein. (377 aa)
	LOC109987600	TNF superfamily member 10; Belongs to the tumor necrosis factor family. (287 aa)

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC109975131	LOC109975928	ENSLBEP00000020348	ENSLBEP00000019952	Uncharacterized protein.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.915
LOC109975131	LOC109982580	ENSLBEP00000020348	ENSLBEP00000010375	Uncharacterized protein.	Fas ligand (TNF superfamily, member 6); Belongs to the tumor necrosis factor family.	0.987
LOC109975131	LOC109984320	ENSLBEP00000020348	ENSLBEP00000022442	Uncharacterized protein.	Caspase 10, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.	0.915
LOC109975131	LOC109987600	ENSLBEP00000020348	ENSLBEP00000037689	Uncharacterized protein.	TNF superfamily member 10; Belongs to the tumor necrosis factor family.	0.780
LOC109975131	LOC109995177	ENSLBEP00000020348	ENSLBEP00000036308	Uncharacterized protein.	Uncharacterized protein.	0.736
LOC109975131	LOC109995578	ENSLBEP00000020348	ENSLBEP00000029624	Uncharacterized protein.	Receptor-interacting serine-threonine kinase 3.	0.646
LOC109975131	LOC109995799	ENSLBEP00000020348	ENSLBEP00000005892	Uncharacterized protein.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.915
LOC109975131	LOC109995961	ENSLBEP00000020348	ENSLBEP00000006015	Uncharacterized protein.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.892
LOC109975131	LOC109998157	ENSLBEP00000020348	ENSLBEP00000016647	Uncharacterized protein.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.646
LOC109975131	LOC109998914	ENSLBEP00000020348	ENSLBEP00000029499	Uncharacterized protein.	Tumor necrosis factor receptor superfamily, member a.	0.827
LOC109975131	MLKL	ENSLBEP00000020348	ENSLBEP00000006884	Uncharacterized protein.	Mixed lineage kinase domain like pseudokinase.	0.417
LOC109975131	cflar	ENSLBEP00000020348	ENSLBEP00000002719	Uncharacterized protein.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.888
LOC109975131	fadd	ENSLBEP00000020348	ENSLBEP00000028812	Uncharacterized protein.	Uncharacterized protein.	0.993
LOC109975928	LOC109975131	ENSLBEP00000019952	ENSLBEP00000020348	Uncharacterized protein; Belongs to the peptidase C14A family.	Uncharacterized protein.	0.915
LOC109975928	LOC109981905	ENSLBEP00000019952	ENSLBEP00000004867	Uncharacterized protein; Belongs to the peptidase C14A family.	Uncharacterized protein.	0.915
LOC109975928	LOC109982580	ENSLBEP00000019952	ENSLBEP00000010375	Uncharacterized protein; Belongs to the peptidase C14A family.	Fas ligand (TNF superfamily, member 6); Belongs to the tumor necrosis factor family.	0.923
LOC109975928	LOC109984320	ENSLBEP00000019952	ENSLBEP00000022442	Uncharacterized protein; Belongs to the peptidase C14A family.	Caspase 10, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.	0.836
LOC109975928	LOC109987600	ENSLBEP00000019952	ENSLBEP00000037689	Uncharacterized protein; Belongs to the peptidase C14A family.	TNF superfamily member 10; Belongs to the tumor necrosis factor family.	0.910
LOC109975928	LOC109995177	ENSLBEP00000019952	ENSLBEP00000036308	Uncharacterized protein; Belongs to the peptidase C14A family.	Uncharacterized protein.	0.697
LOC109975928	LOC109995578	ENSLBEP00000019952	ENSLBEP00000029624	Uncharacterized protein; Belongs to the peptidase C14A family.	Receptor-interacting serine-threonine kinase 3.	0.974