Your Input: | |
| | rchy1 | Uncharacterized protein. (276 aa) |
| | MSH2 | MutS homolog 2. (600 aa) |
| | ENSLBEP00000000333 | Uncharacterized protein. (270 aa) |
| | rfc4 | Replication factor C (activator 1) 4. (358 aa) |
| | ENSLBEP00000000800 | Uncharacterized protein. (66 aa) |
| | pold3 | Polymerase (DNA-directed), delta 3, accessory subunit. (447 aa) |
| | mlh3 | MutL_C domain-containing protein. (382 aa) |
| | zdhhc16 | Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (412 aa) |
| | LOC109987076 | RPA_C domain-containing protein. (257 aa) |
| | dmc1 | Meiotic recombination protein; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks; Belongs to the RecA family. DMC1 subfamily. (332 aa) |
| | ENSLBEP00000001874 | RAD9 checkpoint clamp component B. (188 aa) |
| | pole2 | DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (496 aa) |
| | mcph1 | Uncharacterized protein. (368 aa) |
| | rmi1 | RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae). (657 aa) |
| | LOC109993446 | AAA domain-containing protein. (835 aa) |
| | LOC109984746 | Tower domain-containing protein. (922 aa) |
| | RPA1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (705 aa) |
| | msh4 | MutS homolog 4. (821 aa) |
| | LOC109985360 | BRCA1 associated RING domain 1. (802 aa) |
| | polh | Polymerase (DNA directed), eta. (723 aa) |
| | top3b | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (854 aa) |
| | rfc3 | Replication factor C (activator 1) 3. (356 aa) |
| | smarcal1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily. (869 aa) |
| | rfc1 | Replication factor C subunit 1. (1024 aa) |
| | dhx58 | DEXH (Asp-Glu-X-His) box polypeptide 58. (679 aa) |
| | ENSLBEP00000005965 | RFC1 domain-containing protein. (117 aa) |
| | chtf18 | AAA domain-containing protein. (918 aa) |
| | LOC109984795 | Ring finger and WD repeat domain 3. (715 aa) |
| | ifih1 | Interferon induced with helicase C domain 1. (990 aa) |
| | brca1 | Uncharacterized protein. (1180 aa) |
| | LOC110001535 | CBFD_NFYB_HMF domain-containing protein. (153 aa) |
| | pif1 | ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. (614 aa) |
| | lig1 | DNA ligase. (767 aa) |
| | dscc1 | DNA replication and sister chromatid cohesion 1. (368 aa) |
| | LOC109987772 | SCY domain-containing protein. (126 aa) |
| | pole4 | Polymerase (DNA-directed), epsilon 4, accessory subunit. (129 aa) |
| | chtf8 | CTF8, chromosome transmission fidelity factor 8 homolog (S. cerevisiae). (137 aa) |
| | ENSLBEP00000009084 | Uncharacterized protein. (88 aa) |
| | ENSLBEP00000009224 | MutS homolog 5. (518 aa) |
| | LOC109996043 | Zgc:110269. (347 aa) |
| | spo11 | SPO11 initiator of meiotic double stranded breaks. (390 aa) |
| | MPHOSPH9 | M-phase phosphoprotein 9. (959 aa) |
| | brip1 | BRCA1 interacting protein C-terminal helicase 1. (1553 aa) |
| | rfc5 | Replication factor C (activator 1) 5. (335 aa) |
| | dna2 | DNA replication helicase/nuclease 2. (1384 aa) |
| | LOC109995863 | Uncharacterized protein. (555 aa) |
| | ENSLBEP00000011792 | Uncharacterized protein. (142 aa) |
| | ENSLBEP00000011876 | Uncharacterized protein. (726 aa) |
| | stn1 | CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication. (365 aa) |
| | rad9a | RAD9 checkpoint clamp component A. (372 aa) |
| | pms2 | PMS1 homolog 2, mismatch repair system component. (852 aa) |
| | LOC109975730 | RECA_2 domain-containing protein. (340 aa) |
| | ten1 | TEN1 subunit of CST complex. (134 aa) |
| | rad17 | RAD17 checkpoint clamp loader component. (618 aa) |
| | ENSLBEP00000013814 | FHA domain-containing protein. (1364 aa) |
| | ENSLBEP00000013896 | Uncharacterized protein. (586 aa) |
| | tdrd3 | Tudor domain containing 3. (751 aa) |
| | rev3l | REV3 like, DNA directed polymerase zeta catalytic subunit. (2789 aa) |
| | topbp1 | DNA topoisomerase II binding protein 1. (1444 aa) |
| | atm | Non-specific serine/threonine protein kinase. (3019 aa) |
| | pole | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2259 aa) |
| | LOC109979207 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1148 aa) |
| | prim2 | DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. (495 aa) |
| | mlh1 | MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli). (648 aa) |
| | rfc2 | Replication factor C (activator 1) 2. (233 aa) |
| | msh3 | MutS homolog 3 (E. coli); Component of the post-replicative DNA mismatch repair system (MMR). (1024 aa) |
| | ENSLBEP00000019089 | Uncharacterized protein. (202 aa) |
| | ENSLBEP00000019134 | Chromo_2 domain-containing protein. (634 aa) |
| | pcna | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa) |
| | rtel1 | Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...] (1179 aa) |
| | ENSLBEP00000020673 | RecQ helicase-like 4. (781 aa) |
| | LOC109984378 | Cell division cycle associated 7a. (367 aa) |
| | msh6 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1382 aa) |
| | tp53bp1 | Tumor protein p53 binding protein, 1. (1256 aa) |
| | LOC109976362 | RAD51 paralog C. (342 aa) |
| | LOC110002533 | RECA_2 domain-containing protein. (354 aa) |
| | pola1 | DNA polymerase. (1476 aa) |
| | rad1 | RAD1 homolog (S. pombe). (279 aa) |
| | LOC110002540 | BRCT domain-containing protein. (636 aa) |
| | top3a | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1018 aa) |
| | rev1 | REV1 DNA directed polymerase. (1385 aa) |
| | LOC109982285 | Si:dkey-24l11.2. (620 aa) |
| | ENSLBEP00000024266 | Uncharacterized protein. (200 aa) |
| | ENSLBEP00000024280 | ANK_REP_REGION domain-containing protein. (346 aa) |
| | blm | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (846 aa) |
| | recql5 | RecQ helicase-like 5. (430 aa) |
| | mad2l2 | Mitotic arrest deficient 2 like 2. (210 aa) |
| | LOC110001857 | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (954 aa) |
| | prim1 | DNA primase; Belongs to the eukaryotic-type primase small subunit family. (426 aa) |
| | ddx11 | DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11. (910 aa) |
| | tp73 | Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (652 aa) |
| | hus1 | Checkpoint protein; Belongs to the HUS1 family. (285 aa) |
| | rpa1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (605 aa) |
| | polk | Polymerase (DNA directed) kappa. (395 aa) |
| | pold2 | Polymerase (DNA directed), delta 2, regulatory subunit. (471 aa) |
| | ENSLBEP00000029957 | RING-type domain-containing protein. (504 aa) |
| | LOC109975320 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily. (766 aa) |
| | LOC109975370 | Uncharacterized protein. (330 aa) |
| | pold1 | DNA polymerase. (1126 aa) |
| | rmi2 | RecQ mediated genome instability 2. (144 aa) |
| | fbh1 | F-box DNA helicase 1. (1069 aa) |
| | xrcc2 | RECA_2 domain-containing protein. (304 aa) |
| | exo1 | Exonuclease 1. (793 aa) |
| | LOC110003393 | DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily. (334 aa) |
| | meiob | Methionine sulfoxide reductase B1b. (438 aa) |
| | primpol | Primase and polymerase (DNA-directed). (539 aa) |
| | fen1 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (380 aa) |
| | wdhd1 | WD repeat and HMG-box DNA binding protein 1. (1135 aa) |
| | rad50 | RAD50 homolog, double strand break repair protein. (1284 aa) |
| | atrip | Uncharacterized protein. (832 aa) |
| | tp63 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (631 aa) |
| | mre11 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (641 aa) |
| | rad51 | DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (338 aa) |
| | rhno1 | Si:ch73-352p4.5. (279 aa) |
| | rad51d | RAD51 paralog D. (334 aa) |
| | zdhhc15 | Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (313 aa) |
| | poli | Polymerase (DNA directed) iota. (684 aa) |
| | msh2 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (935 aa) |
| | pola2 | DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (600 aa) |
| | rpa2 | Replication protein A2. (274 aa) |
| | rpa3 | Replication protein A3. (122 aa) |
| | zranb3 | Zinc finger, RAN-binding domain containing 3. (1192 aa) |
| | pms1 | PMS1 homolog 1, mismatch repair system component. (1093 aa) |
| | ENSLBEP00000037734 | SAE2 domain-containing protein. (93 aa) |
| | atr | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2437 aa) |
| | LOC110002098 | Exonuclease 3'-5' domain containing 2. (633 aa) |
