(19 nodes) Isoprenoid biosynthetic process, and Protein farnesyltransferase complex network (Labrus bergylta)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Your Input:
	LOC109989429	3-hydroxy-3-methylglutaryl coenzyme A reductase. (885 aa)
	mvd	Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes. (402 aa)
	dhdds	Alkyl transferase; Belongs to the UPP synthase family. (335 aa)
	LOC110006114	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (357 aa)
	pdss1	Prenyl (decaprenyl) diphosphate synthase, subunit 1; Belongs to the FPP/GGPP synthase family. (422 aa)
	LOC109980473	Uncharacterized protein. (153 aa)
	mvk	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (397 aa)
	RUSC2	RUN and SH3 domain containing 2. (919 aa)
	ENSLBEP00000022123	RUN and SH3 domain containing 2. (629 aa)
	ENSLBEP00000025014	WD_REPEATS_REGION domain-containing protein. (552 aa)
	LOC109983288	F-box protein 30b. (735 aa)
	churc1	Churchill domain containing 1. (112 aa)
	pdss2	Prenyl (decaprenyl) diphosphate synthase, subunit 2; Belongs to the FPP/GGPP synthase family. (384 aa)
	nus1	NUS1 dehydrodolichyl diphosphate synthase subunit. (292 aa)
	pyroxd2	Pyridine nucleotide-disulphide oxidoreductase domain 2. (582 aa)
	rusc1	RUN and SH3 domain containing 1. (1216 aa)
	fdps	Uncharacterized protein; Belongs to the FPP/GGPP synthase family. (358 aa)
	ENSLBEP00000037562	3-hydroxy-3-methylglutaryl coenzyme A reductase. (888 aa)
	idi1	Isopentenyl-diphosphate delta isomerase 1. (288 aa)

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSLBEP00000022123	ENSLBEP00000025014	ENSLBEP00000022123	ENSLBEP00000025014	RUN and SH3 domain containing 2.	WD_REPEATS_REGION domain-containing protein.	0.808
ENSLBEP00000022123	ENSLBEP00000037562	ENSLBEP00000022123	ENSLBEP00000037562	RUN and SH3 domain containing 2.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.494
ENSLBEP00000022123	LOC109989429	ENSLBEP00000022123	ENSLBEP00000004610	RUN and SH3 domain containing 2.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.494
ENSLBEP00000022123	LOC110006114	ENSLBEP00000022123	ENSLBEP00000011276	RUN and SH3 domain containing 2.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.578
ENSLBEP00000022123	RUSC2	ENSLBEP00000022123	ENSLBEP00000022013	RUN and SH3 domain containing 2.	RUN and SH3 domain containing 2.	0.927
ENSLBEP00000022123	churc1	ENSLBEP00000022123	ENSLBEP00000027537	RUN and SH3 domain containing 2.	Churchill domain containing 1.	0.661
ENSLBEP00000022123	dhdds	ENSLBEP00000022123	ENSLBEP00000010065	RUN and SH3 domain containing 2.	Alkyl transferase; Belongs to the UPP synthase family.	0.780
ENSLBEP00000022123	idi1	ENSLBEP00000022123	ENSLBEP00000037669	RUN and SH3 domain containing 2.	Isopentenyl-diphosphate delta isomerase 1.	0.839
ENSLBEP00000022123	mvd	ENSLBEP00000022123	ENSLBEP00000009914	RUN and SH3 domain containing 2.	Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes.	0.900
ENSLBEP00000022123	mvk	ENSLBEP00000022123	ENSLBEP00000014972	RUN and SH3 domain containing 2.	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.	0.426
ENSLBEP00000022123	nus1	ENSLBEP00000022123	ENSLBEP00000028890	RUN and SH3 domain containing 2.	NUS1 dehydrodolichyl diphosphate synthase subunit.	0.759
ENSLBEP00000022123	pdss1	ENSLBEP00000022123	ENSLBEP00000013226	RUN and SH3 domain containing 2.	Prenyl (decaprenyl) diphosphate synthase, subunit 1; Belongs to the FPP/GGPP synthase family.	0.732
ENSLBEP00000022123	pdss2	ENSLBEP00000022123	ENSLBEP00000027809	RUN and SH3 domain containing 2.	Prenyl (decaprenyl) diphosphate synthase, subunit 2; Belongs to the FPP/GGPP synthase family.	0.732
ENSLBEP00000022123	pyroxd2	ENSLBEP00000022123	ENSLBEP00000031886	RUN and SH3 domain containing 2.	Pyridine nucleotide-disulphide oxidoreductase domain 2.	0.612
ENSLBEP00000025014	ENSLBEP00000022123	ENSLBEP00000025014	ENSLBEP00000022123	WD_REPEATS_REGION domain-containing protein.	RUN and SH3 domain containing 2.	0.808
ENSLBEP00000025014	ENSLBEP00000037562	ENSLBEP00000025014	ENSLBEP00000037562	WD_REPEATS_REGION domain-containing protein.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.514
ENSLBEP00000025014	LOC109980473	ENSLBEP00000025014	ENSLBEP00000013770	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein.	0.808
ENSLBEP00000025014	LOC109983288	ENSLBEP00000025014	ENSLBEP00000026052	WD_REPEATS_REGION domain-containing protein.	F-box protein 30b.	0.808
ENSLBEP00000025014	LOC109989429	ENSLBEP00000025014	ENSLBEP00000004610	WD_REPEATS_REGION domain-containing protein.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.514
ENSLBEP00000025014	LOC110006114	ENSLBEP00000025014	ENSLBEP00000011276	WD_REPEATS_REGION domain-containing protein.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.773