(5 nodes) Sterol biosynthesis, and Coenzyme A binding network (Labrus bergylta)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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Your Input:
	LOC109989429	3-hydroxy-3-methylglutaryl coenzyme A reductase. (885 aa)
	mvd	Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes. (402 aa)
	LOC110006114	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (357 aa)
	mvk	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (397 aa)
	ENSLBEP00000037562	3-hydroxy-3-methylglutaryl coenzyme A reductase. (888 aa)

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSLBEP00000037562	LOC109989429	ENSLBEP00000037562	ENSLBEP00000004610	3-hydroxy-3-methylglutaryl coenzyme A reductase.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.841
ENSLBEP00000037562	LOC110006114	ENSLBEP00000037562	ENSLBEP00000011276	3-hydroxy-3-methylglutaryl coenzyme A reductase.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.985
ENSLBEP00000037562	mvd	ENSLBEP00000037562	ENSLBEP00000009914	3-hydroxy-3-methylglutaryl coenzyme A reductase.	Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes.	0.941
ENSLBEP00000037562	mvk	ENSLBEP00000037562	ENSLBEP00000014972	3-hydroxy-3-methylglutaryl coenzyme A reductase.	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.	0.947
LOC109989429	ENSLBEP00000037562	ENSLBEP00000004610	ENSLBEP00000037562	3-hydroxy-3-methylglutaryl coenzyme A reductase.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.841
LOC109989429	LOC110006114	ENSLBEP00000004610	ENSLBEP00000011276	3-hydroxy-3-methylglutaryl coenzyme A reductase.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.989
LOC109989429	mvd	ENSLBEP00000004610	ENSLBEP00000009914	3-hydroxy-3-methylglutaryl coenzyme A reductase.	Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes.	0.943
LOC109989429	mvk	ENSLBEP00000004610	ENSLBEP00000014972	3-hydroxy-3-methylglutaryl coenzyme A reductase.	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.	0.949
LOC110006114	ENSLBEP00000037562	ENSLBEP00000011276	ENSLBEP00000037562	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.985
LOC110006114	LOC109989429	ENSLBEP00000011276	ENSLBEP00000004610	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.989
LOC110006114	mvd	ENSLBEP00000011276	ENSLBEP00000009914	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes.	0.928
LOC110006114	mvk	ENSLBEP00000011276	ENSLBEP00000014972	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.	0.950
mvd	ENSLBEP00000037562	ENSLBEP00000009914	ENSLBEP00000037562	Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.941
mvd	LOC109989429	ENSLBEP00000009914	ENSLBEP00000004610	Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.943
mvd	LOC110006114	ENSLBEP00000009914	ENSLBEP00000011276	Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.928
mvd	mvk	ENSLBEP00000009914	ENSLBEP00000014972	Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes.	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.	0.996
mvk	ENSLBEP00000037562	ENSLBEP00000014972	ENSLBEP00000037562	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.947
mvk	LOC109989429	ENSLBEP00000014972	ENSLBEP00000004610	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.949
mvk	LOC110006114	ENSLBEP00000014972	ENSLBEP00000011276	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.950
mvk	mvd	ENSLBEP00000014972	ENSLBEP00000009914	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.	Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes.	0.996