(27 nodes) G protein-coupled glutamate receptor signaling pathway, and GPCR family 3, GABA-B receptor network (Labrus bergylta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC109982440	Gamma-aminobutyric acid (GABA) B receptor, 2. (913 aa)
	grm8	Glutamate metabotropic receptor 8. (865 aa)
	LOC109987722	BAALC binder of MAP3K1 and KLF4 b. (181 aa)
	HOMER1	Homer scaffold protein 1. (356 aa)
	LOC109984851	Glutamate receptor, metabotropic 8b. (920 aa)
	GRM5	Glutamate receptor, metabotropic 5b. (917 aa)
	LOC109977692	Glutamate receptor, metabotropic 1b. (1160 aa)
	LOC109986834	G_PROTEIN_RECEP_F3_4 domain-containing protein. (917 aa)
	ENSLBEP00000011464	ANF_receptor domain-containing protein. (282 aa)
	GRM7	Glutamate metabotropic receptor 7. (844 aa)
	LOC109990118	Glutamate receptor, metabotropic 2a. (893 aa)
	ENSLBEP00000017284	ANF_receptor domain-containing protein. (435 aa)
	LOC109988368	Glutamate receptor, metabotropic 5a. (1146 aa)
	LOC109991965	WH1 domain-containing protein. (363 aa)
	LOC109998752	Homer scaffold protein 1b. (363 aa)
	AGAP2	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2. (1122 aa)
	LOC110002528	G_PROTEIN_RECEP_F3_4 domain-containing protein. (906 aa)
	LOC109983910	Glutamate receptor, metabotropic 6b. (886 aa)
	LOC110003859	G protein-coupled receptor 156. (506 aa)
	grm1	Glutamate receptor, metabotropic 1a. (1169 aa)
	LOC109980610	Glutamate receptor, metabotropic 2b. (896 aa)
	LOC109985745	Olfactory receptor C family, h1. (826 aa)
	LOC109985801	G_PROTEIN_RECEP_F3_4 domain-containing protein. (857 aa)
	LOC109981743	Glutamate receptor, metabotropic 4. (929 aa)
	homer2	Homer scaffold protein 2. (356 aa)
	LOC110002772	Glutamate receptor, metabotropic 3. (870 aa)
	homer3	Homer scaffold protein 3b. (360 aa)

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGAP2	ENSLBEP00000011464	ENSLBEP00000021970	ENSLBEP00000011464	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2.	ANF_receptor domain-containing protein.	0.800
AGAP2	ENSLBEP00000017284	ENSLBEP00000021970	ENSLBEP00000017284	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2.	ANF_receptor domain-containing protein.	0.522
AGAP2	GRM5	ENSLBEP00000021970	ENSLBEP00000006184	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2.	Glutamate receptor, metabotropic 5b.	0.800
AGAP2	GRM7	ENSLBEP00000021970	ENSLBEP00000014718	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2.	Glutamate metabotropic receptor 7.	0.520
AGAP2	LOC109977692	ENSLBEP00000021970	ENSLBEP00000006580	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2.	Glutamate receptor, metabotropic 1b.	0.800
AGAP2	LOC109980610	ENSLBEP00000021970	ENSLBEP00000027188	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2.	Glutamate receptor, metabotropic 2b.	0.522
AGAP2	LOC109981743	ENSLBEP00000021970	ENSLBEP00000031861	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2.	Glutamate receptor, metabotropic 4.	0.520
AGAP2	LOC109983910	ENSLBEP00000021970	ENSLBEP00000024335	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2.	Glutamate receptor, metabotropic 6b.	0.520
AGAP2	LOC109984851	ENSLBEP00000021970	ENSLBEP00000004593	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2.	Glutamate receptor, metabotropic 8b.	0.520
AGAP2	LOC109985745	ENSLBEP00000021970	ENSLBEP00000031706	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2.	Olfactory receptor C family, h1.	0.417
AGAP2	LOC109985801	ENSLBEP00000021970	ENSLBEP00000031804	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2.	G_PROTEIN_RECEP_F3_4 domain-containing protein.	0.417
AGAP2	LOC109986834	ENSLBEP00000021970	ENSLBEP00000011413	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2.	G_PROTEIN_RECEP_F3_4 domain-containing protein.	0.520
AGAP2	LOC109988368	ENSLBEP00000021970	ENSLBEP00000018403	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2.	Glutamate receptor, metabotropic 5a.	0.800
AGAP2	LOC109990118	ENSLBEP00000021970	ENSLBEP00000015450	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2.	Glutamate receptor, metabotropic 2a.	0.522
AGAP2	LOC110002528	ENSLBEP00000021970	ENSLBEP00000022423	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2.	G_PROTEIN_RECEP_F3_4 domain-containing protein.	0.520
AGAP2	LOC110002772	ENSLBEP00000021970	ENSLBEP00000034541	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2.	Glutamate receptor, metabotropic 3.	0.522
AGAP2	grm1	ENSLBEP00000021970	ENSLBEP00000026121	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2.	Glutamate receptor, metabotropic 1a.	0.854
AGAP2	grm8	ENSLBEP00000021970	ENSLBEP00000001482	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2.	Glutamate metabotropic receptor 8.	0.520
ENSLBEP00000011464	AGAP2	ENSLBEP00000011464	ENSLBEP00000021970	ANF_receptor domain-containing protein.	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2.	0.800
ENSLBEP00000011464	ENSLBEP00000017284	ENSLBEP00000011464	ENSLBEP00000017284	ANF_receptor domain-containing protein.	ANF_receptor domain-containing protein.	0.513