(25 nodes) Mixed, incl. TNFs bind their physiological receptors, and TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway network (Labrus bergylta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC109998562	TNF superfamily member 13b; Belongs to the tumor necrosis factor family. (260 aa)
	ENSLBEP00000007902	TNFR-Cys domain-containing protein. (305 aa)
	ENSLBEP00000008609	Tumor necrosis factor receptor superfamily, member 11a, NFKB activator. (402 aa)
	ENSLBEP00000012259	TNFR-Cys domain-containing protein. (265 aa)
	ENSLBEP00000012344	TNFR-Cys domain-containing protein. (265 aa)
	cd40lg	CD40 ligand; Belongs to the tumor necrosis factor family. (238 aa)
	LOC109987883	TNFR-Cys domain-containing protein. (327 aa)
	LOC109996990	CD40 molecule, TNF receptor superfamily member 5. (308 aa)
	LOC109995405	Uncharacterized protein. (333 aa)
	LOC109989552	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (282 aa)
	LOC110004603	Uncharacterized protein. (300 aa)
	LOC110006283	TNFR-Cys domain-containing protein. (284 aa)
	LOC110004603-2	Uncharacterized protein. (288 aa)
	LOC109981531	TNFR-Cys domain-containing protein. (241 aa)
	LOC109981508	Uncharacterized protein. (280 aa)
	traf3	TNF receptor-associated factor 3. (666 aa)
	LOC109986980	TNF superfamily member 11; Belongs to the tumor necrosis factor family. (268 aa)
	TNFRSF11B	TNF receptor superfamily member 11b. (414 aa)
	LOC109984427	Uncharacterized protein. (287 aa)
	LOC109997856	Mitogen-activated protein kinase kinase kinase 14a. (855 aa)
	LOC109989247	TNF superfamily member 14; Belongs to the tumor necrosis factor family. (237 aa)
	ENSLBEP00000033040	Ig-like domain-containing protein. (224 aa)
	btla	Ig-like domain-containing protein. (310 aa)
	LOC109995681	Uncharacterized protein. (307 aa)
	tnfsf12	TNF superfamily member 12; Belongs to the tumor necrosis factor family. (246 aa)

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSLBEP00000007902	ENSLBEP00000012259	ENSLBEP00000007902	ENSLBEP00000012259	TNFR-Cys domain-containing protein.	TNFR-Cys domain-containing protein.	0.483
ENSLBEP00000007902	ENSLBEP00000012344	ENSLBEP00000007902	ENSLBEP00000012344	TNFR-Cys domain-containing protein.	TNFR-Cys domain-containing protein.	0.481
ENSLBEP00000007902	LOC109981508	ENSLBEP00000007902	ENSLBEP00000021874	TNFR-Cys domain-containing protein.	Uncharacterized protein.	0.490
ENSLBEP00000007902	LOC109981531	ENSLBEP00000007902	ENSLBEP00000021822	TNFR-Cys domain-containing protein.	TNFR-Cys domain-containing protein.	0.488
ENSLBEP00000007902	LOC109996990	ENSLBEP00000007902	ENSLBEP00000016101	TNFR-Cys domain-containing protein.	CD40 molecule, TNF receptor superfamily member 5.	0.480
ENSLBEP00000007902	LOC110004603	ENSLBEP00000007902	ENSLBEP00000017779	TNFR-Cys domain-containing protein.	Uncharacterized protein.	0.438
ENSLBEP00000007902	LOC110004603-2	ENSLBEP00000007902	ENSLBEP00000017847	TNFR-Cys domain-containing protein.	Uncharacterized protein.	0.436
ENSLBEP00000007902	LOC110006283	ENSLBEP00000007902	ENSLBEP00000017834	TNFR-Cys domain-containing protein.	TNFR-Cys domain-containing protein.	0.491
ENSLBEP00000008609	ENSLBEP00000012259	ENSLBEP00000008609	ENSLBEP00000012259	Tumor necrosis factor receptor superfamily, member 11a, NFKB activator.	TNFR-Cys domain-containing protein.	0.586
ENSLBEP00000008609	ENSLBEP00000012344	ENSLBEP00000008609	ENSLBEP00000012344	Tumor necrosis factor receptor superfamily, member 11a, NFKB activator.	TNFR-Cys domain-containing protein.	0.586
ENSLBEP00000008609	LOC109981508	ENSLBEP00000008609	ENSLBEP00000021874	Tumor necrosis factor receptor superfamily, member 11a, NFKB activator.	Uncharacterized protein.	0.586
ENSLBEP00000008609	LOC109981531	ENSLBEP00000008609	ENSLBEP00000021822	Tumor necrosis factor receptor superfamily, member 11a, NFKB activator.	TNFR-Cys domain-containing protein.	0.586
ENSLBEP00000008609	LOC109986980	ENSLBEP00000008609	ENSLBEP00000027904	Tumor necrosis factor receptor superfamily, member 11a, NFKB activator.	TNF superfamily member 11; Belongs to the tumor necrosis factor family.	0.995
ENSLBEP00000008609	LOC109989552	ENSLBEP00000008609	ENSLBEP00000016335	Tumor necrosis factor receptor superfamily, member 11a, NFKB activator.	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	0.677
ENSLBEP00000008609	LOC109995405	ENSLBEP00000008609	ENSLBEP00000016226	Tumor necrosis factor receptor superfamily, member 11a, NFKB activator.	Uncharacterized protein.	0.724
ENSLBEP00000008609	LOC109995681	ENSLBEP00000008609	ENSLBEP00000034912	Tumor necrosis factor receptor superfamily, member 11a, NFKB activator.	Uncharacterized protein.	0.586
ENSLBEP00000008609	LOC109996990	ENSLBEP00000008609	ENSLBEP00000016101	Tumor necrosis factor receptor superfamily, member 11a, NFKB activator.	CD40 molecule, TNF receptor superfamily member 5.	0.588
ENSLBEP00000008609	LOC109997856	ENSLBEP00000008609	ENSLBEP00000030958	Tumor necrosis factor receptor superfamily, member 11a, NFKB activator.	Mitogen-activated protein kinase kinase kinase 14a.	0.729
ENSLBEP00000008609	LOC109998562	ENSLBEP00000008609	ENSLBEP00000002973	Tumor necrosis factor receptor superfamily, member 11a, NFKB activator.	TNF superfamily member 13b; Belongs to the tumor necrosis factor family.	0.719
ENSLBEP00000008609	LOC110004603	ENSLBEP00000008609	ENSLBEP00000017779	Tumor necrosis factor receptor superfamily, member 11a, NFKB activator.	Uncharacterized protein.	0.586