(12 nodes) Mixed, incl. ER ubiquitin ligase complex, and Protein OS-9-like network (Labrus bergylta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSLBEP00000002046	Uncharacterized protein. (582 aa)
	LOC109976776	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (239 aa)
	LOC109994608	Uncharacterized protein. (1599 aa)
	derl1	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (250 aa)
	AMFR	Autocrine motility factor receptor b. (620 aa)
	LOC109984849	Uncharacterized protein. (648 aa)
	erlec1	Endoplasmic reticulum lectin 1. (485 aa)
	os9	OS9 endoplasmic reticulum lectin. (692 aa)
	LOC109988506	Derlin-2. (239 aa)
	LOC109983321	Uncharacterized protein. (1099 aa)
	sel1l	SEL1L adaptor subunit of ERAD E3 ubiquitin ligase. (813 aa)
	syvn1	Synovial apoptosis inhibitor 1, synoviolin. (702 aa)

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AMFR	ENSLBEP00000002046	ENSLBEP00000007588	ENSLBEP00000002046	Autocrine motility factor receptor b.	Uncharacterized protein.	0.880
AMFR	LOC109976776	ENSLBEP00000007588	ENSLBEP00000004317	Autocrine motility factor receptor b.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.963
AMFR	LOC109983321	ENSLBEP00000007588	ENSLBEP00000030495	Autocrine motility factor receptor b.	Uncharacterized protein.	0.911
AMFR	LOC109984849	ENSLBEP00000007588	ENSLBEP00000007919	Autocrine motility factor receptor b.	Uncharacterized protein.	0.836
AMFR	LOC109988506	ENSLBEP00000007588	ENSLBEP00000025383	Autocrine motility factor receptor b.	Derlin-2.	0.963
AMFR	LOC109994608	ENSLBEP00000007588	ENSLBEP00000006159	Autocrine motility factor receptor b.	Uncharacterized protein.	0.911
AMFR	derl1	ENSLBEP00000007588	ENSLBEP00000007466	Autocrine motility factor receptor b.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.980
AMFR	erlec1	ENSLBEP00000007588	ENSLBEP00000014466	Autocrine motility factor receptor b.	Endoplasmic reticulum lectin 1.	0.962
AMFR	os9	ENSLBEP00000007588	ENSLBEP00000025373	Autocrine motility factor receptor b.	OS9 endoplasmic reticulum lectin.	0.962
AMFR	sel1l	ENSLBEP00000007588	ENSLBEP00000031499	Autocrine motility factor receptor b.	SEL1L adaptor subunit of ERAD E3 ubiquitin ligase.	0.961
ENSLBEP00000002046	AMFR	ENSLBEP00000002046	ENSLBEP00000007588	Uncharacterized protein.	Autocrine motility factor receptor b.	0.880
ENSLBEP00000002046	LOC109976776	ENSLBEP00000002046	ENSLBEP00000004317	Uncharacterized protein.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.914
ENSLBEP00000002046	LOC109983321	ENSLBEP00000002046	ENSLBEP00000030495	Uncharacterized protein.	Uncharacterized protein.	0.846
ENSLBEP00000002046	LOC109984849	ENSLBEP00000002046	ENSLBEP00000007919	Uncharacterized protein.	Uncharacterized protein.	0.880
ENSLBEP00000002046	LOC109988506	ENSLBEP00000002046	ENSLBEP00000025383	Uncharacterized protein.	Derlin-2.	0.914
ENSLBEP00000002046	LOC109994608	ENSLBEP00000002046	ENSLBEP00000006159	Uncharacterized protein.	Uncharacterized protein.	0.846
ENSLBEP00000002046	derl1	ENSLBEP00000002046	ENSLBEP00000007466	Uncharacterized protein.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.963
ENSLBEP00000002046	erlec1	ENSLBEP00000002046	ENSLBEP00000014466	Uncharacterized protein.	Endoplasmic reticulum lectin 1.	0.908
ENSLBEP00000002046	os9	ENSLBEP00000002046	ENSLBEP00000025373	Uncharacterized protein.	OS9 endoplasmic reticulum lectin.	0.908
ENSLBEP00000002046	sel1l	ENSLBEP00000002046	ENSLBEP00000031499	Uncharacterized protein.	SEL1L adaptor subunit of ERAD E3 ubiquitin ligase.	0.890