(19 nodes) Mixed, incl. Grb2-like, and Tyrosine-protein kinase, HGF/MSP receptor network (Labrus bergylta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	gab2	GRB2-associated binding protein 2. (645 aa)
	ENSLBEP00000002343	Ras-GEF domain-containing protein. (394 aa)
	LOC109995748	GRB2 related adaptor protein a. (216 aa)
	met	MET proto-oncogene, receptor tyrosine kinase. (1423 aa)
	LOC109988278	GRB2 related adaptor protein b. (258 aa)
	LOC109984174	Receptor protein-tyrosine kinase. (742 aa)
	LOC109988924	Uncharacterized protein. (875 aa)
	LOC109991029	GRB2 related adaptor protein 2b. (237 aa)
	ptpn6	Protein tyrosine phosphatase non-receptor type 6. (582 aa)
	ptpn11	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (602 aa)
	sos2	Son of sevenless homolog 2 (Drosophila). (1067 aa)
	grb2	Growth factor receptor bound protein 2. (230 aa)
	gab1	GRB2-associated binding protein 1. (707 aa)
	mst1r	Macrophage stimulating 1 receptor b. (1370 aa)
	cbl	Cbl proto-oncogene, E3 ubiquitin protein ligase. (960 aa)
	LOC109992267	Receptor protein-tyrosine kinase. (1184 aa)
	LOC109980643	Macrophage stimulating 1 receptor a. (1394 aa)
	LOC109996168	Tyrosine-protein kinase receptor. (1531 aa)
	cblb	Cbl proto-oncogene B, E3 ubiquitin protein ligase. (955 aa)

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSLBEP00000002343	LOC109980643	ENSLBEP00000002343	ENSLBEP00000027888	Ras-GEF domain-containing protein.	Macrophage stimulating 1 receptor a.	0.742
ENSLBEP00000002343	LOC109984174	ENSLBEP00000002343	ENSLBEP00000009850	Ras-GEF domain-containing protein.	Receptor protein-tyrosine kinase.	0.834
ENSLBEP00000002343	LOC109988278	ENSLBEP00000002343	ENSLBEP00000006628	Ras-GEF domain-containing protein.	GRB2 related adaptor protein b.	0.796
ENSLBEP00000002343	LOC109988924	ENSLBEP00000002343	ENSLBEP00000011455	Ras-GEF domain-containing protein.	Uncharacterized protein.	0.657
ENSLBEP00000002343	LOC109991029	ENSLBEP00000002343	ENSLBEP00000015433	Ras-GEF domain-containing protein.	GRB2 related adaptor protein 2b.	0.829
ENSLBEP00000002343	LOC109992267	ENSLBEP00000002343	ENSLBEP00000027561	Ras-GEF domain-containing protein.	Receptor protein-tyrosine kinase.	0.940
ENSLBEP00000002343	LOC109995748	ENSLBEP00000002343	ENSLBEP00000003377	Ras-GEF domain-containing protein.	GRB2 related adaptor protein a.	0.796
ENSLBEP00000002343	LOC109996168	ENSLBEP00000002343	ENSLBEP00000028143	Ras-GEF domain-containing protein.	Tyrosine-protein kinase receptor.	0.626
ENSLBEP00000002343	cbl	ENSLBEP00000002343	ENSLBEP00000027006	Ras-GEF domain-containing protein.	Cbl proto-oncogene, E3 ubiquitin protein ligase.	0.657
ENSLBEP00000002343	cblb	ENSLBEP00000002343	ENSLBEP00000028893	Ras-GEF domain-containing protein.	Cbl proto-oncogene B, E3 ubiquitin protein ligase.	0.657
ENSLBEP00000002343	gab1	ENSLBEP00000002343	ENSLBEP00000023481	Ras-GEF domain-containing protein.	GRB2-associated binding protein 1.	0.822
ENSLBEP00000002343	gab2	ENSLBEP00000002343	ENSLBEP00000001020	Ras-GEF domain-containing protein.	GRB2-associated binding protein 2.	0.849
ENSLBEP00000002343	grb2	ENSLBEP00000002343	ENSLBEP00000022583	Ras-GEF domain-containing protein.	Growth factor receptor bound protein 2.	0.988
ENSLBEP00000002343	met	ENSLBEP00000002343	ENSLBEP00000003943	Ras-GEF domain-containing protein.	MET proto-oncogene, receptor tyrosine kinase.	0.742
ENSLBEP00000002343	mst1r	ENSLBEP00000002343	ENSLBEP00000024621	Ras-GEF domain-containing protein.	Macrophage stimulating 1 receptor b.	0.742
ENSLBEP00000002343	ptpn11	ENSLBEP00000002343	ENSLBEP00000018954	Ras-GEF domain-containing protein.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.923
ENSLBEP00000002343	ptpn6	ENSLBEP00000002343	ENSLBEP00000016152	Ras-GEF domain-containing protein.	Protein tyrosine phosphatase non-receptor type 6.	0.923
ENSLBEP00000002343	sos2	ENSLBEP00000002343	ENSLBEP00000021805	Ras-GEF domain-containing protein.	Son of sevenless homolog 2 (Drosophila).	0.900
LOC109980643	ENSLBEP00000002343	ENSLBEP00000027888	ENSLBEP00000002343	Macrophage stimulating 1 receptor a.	Ras-GEF domain-containing protein.	0.742
LOC109980643	LOC109984174	ENSLBEP00000027888	ENSLBEP00000009850	Macrophage stimulating 1 receptor a.	Receptor protein-tyrosine kinase.	0.946