(7 nodes) Mixed, incl. PTK6 Down-Regulation, and CSK-like, SH2 domain network (Labrus bergylta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC109987710	Tyrosine-protein kinase. (537 aa)
	ptk6	Tyrosine-protein kinase. (530 aa)
	ENSLBEP00000012879	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (294 aa)
	sh2d1a	SH2 domain containing 1A duplicate b. (156 aa)
	LOC110005905	Ig-like domain-containing protein. (310 aa)
	CSK	Tyrosine-protein kinase. (357 aa)
	LOC109980661	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (188 aa)

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CSK	ENSLBEP00000012879	ENSLBEP00000023504	ENSLBEP00000012879	Tyrosine-protein kinase.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.738
CSK	LOC109980661	ENSLBEP00000023504	ENSLBEP00000027052	Tyrosine-protein kinase.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.607
CSK	LOC109987710	ENSLBEP00000023504	ENSLBEP00000002513	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.738
CSK	LOC110005905	ENSLBEP00000023504	ENSLBEP00000021497	Tyrosine-protein kinase.	Ig-like domain-containing protein.	0.543
CSK	ptk6	ENSLBEP00000023504	ENSLBEP00000012731	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.738
CSK	sh2d1a	ENSLBEP00000023504	ENSLBEP00000019534	Tyrosine-protein kinase.	SH2 domain containing 1A duplicate b.	0.755
ENSLBEP00000012879	CSK	ENSLBEP00000012879	ENSLBEP00000023504	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Tyrosine-protein kinase.	0.738
ENSLBEP00000012879	LOC109980661	ENSLBEP00000012879	ENSLBEP00000027052	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.767
ENSLBEP00000012879	LOC109987710	ENSLBEP00000012879	ENSLBEP00000002513	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Tyrosine-protein kinase.	0.645
ENSLBEP00000012879	LOC110005905	ENSLBEP00000012879	ENSLBEP00000021497	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Ig-like domain-containing protein.	0.543
ENSLBEP00000012879	ptk6	ENSLBEP00000012879	ENSLBEP00000012731	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Tyrosine-protein kinase.	0.442
ENSLBEP00000012879	sh2d1a	ENSLBEP00000012879	ENSLBEP00000019534	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	SH2 domain containing 1A duplicate b.	0.920
LOC109980661	CSK	ENSLBEP00000027052	ENSLBEP00000023504	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Tyrosine-protein kinase.	0.607
LOC109980661	ENSLBEP00000012879	ENSLBEP00000027052	ENSLBEP00000012879	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.767
LOC109980661	LOC109987710	ENSLBEP00000027052	ENSLBEP00000002513	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Tyrosine-protein kinase.	0.721
LOC109980661	ptk6	ENSLBEP00000027052	ENSLBEP00000012731	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Tyrosine-protein kinase.	0.767
LOC109987710	CSK	ENSLBEP00000002513	ENSLBEP00000023504	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.738
LOC109987710	ENSLBEP00000012879	ENSLBEP00000002513	ENSLBEP00000012879	Tyrosine-protein kinase.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.645
LOC109987710	LOC109980661	ENSLBEP00000002513	ENSLBEP00000027052	Tyrosine-protein kinase.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.721
LOC109987710	LOC110005905	ENSLBEP00000002513	ENSLBEP00000021497	Tyrosine-protein kinase.	Ig-like domain-containing protein.	0.543