(5 nodes) Signal complex assembly, and Leupaxin/Paxillin/TGFB1I1 network (Labrus bergylta)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC109981137	G protein-coupled receptor kinase interacting ArfGAP 2b. (663 aa)
	LOC109989160	PDZ and LIM domain 5a. (577 aa)
	TGFB1I1	Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. (475 aa)
	ENSLBEP00000030475	Focal_AT domain-containing protein. (115 aa)
	ENSLBEP00000030746	FERM domain-containing protein. (273 aa)

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSLBEP00000030475	ENSLBEP00000030746	ENSLBEP00000030475	ENSLBEP00000030746	Focal_AT domain-containing protein.	FERM domain-containing protein.	0.900
ENSLBEP00000030475	LOC109981137	ENSLBEP00000030475	ENSLBEP00000022946	Focal_AT domain-containing protein.	G protein-coupled receptor kinase interacting ArfGAP 2b.	0.531
ENSLBEP00000030475	LOC109989160	ENSLBEP00000030475	ENSLBEP00000026754	Focal_AT domain-containing protein.	PDZ and LIM domain 5a.	0.786
ENSLBEP00000030475	TGFB1I1	ENSLBEP00000030475	ENSLBEP00000029438	Focal_AT domain-containing protein.	Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways.	0.851
ENSLBEP00000030746	ENSLBEP00000030475	ENSLBEP00000030746	ENSLBEP00000030475	FERM domain-containing protein.	Focal_AT domain-containing protein.	0.900
ENSLBEP00000030746	LOC109981137	ENSLBEP00000030746	ENSLBEP00000022946	FERM domain-containing protein.	G protein-coupled receptor kinase interacting ArfGAP 2b.	0.521
ENSLBEP00000030746	LOC109989160	ENSLBEP00000030746	ENSLBEP00000026754	FERM domain-containing protein.	PDZ and LIM domain 5a.	0.786
ENSLBEP00000030746	TGFB1I1	ENSLBEP00000030746	ENSLBEP00000029438	FERM domain-containing protein.	Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways.	0.786
LOC109981137	ENSLBEP00000030475	ENSLBEP00000022946	ENSLBEP00000030475	G protein-coupled receptor kinase interacting ArfGAP 2b.	Focal_AT domain-containing protein.	0.531
LOC109981137	ENSLBEP00000030746	ENSLBEP00000022946	ENSLBEP00000030746	G protein-coupled receptor kinase interacting ArfGAP 2b.	FERM domain-containing protein.	0.521
LOC109981137	LOC109989160	ENSLBEP00000022946	ENSLBEP00000026754	G protein-coupled receptor kinase interacting ArfGAP 2b.	PDZ and LIM domain 5a.	0.804
LOC109981137	TGFB1I1	ENSLBEP00000022946	ENSLBEP00000029438	G protein-coupled receptor kinase interacting ArfGAP 2b.	Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways.	0.906
LOC109989160	ENSLBEP00000030475	ENSLBEP00000026754	ENSLBEP00000030475	PDZ and LIM domain 5a.	Focal_AT domain-containing protein.	0.786
LOC109989160	ENSLBEP00000030746	ENSLBEP00000026754	ENSLBEP00000030746	PDZ and LIM domain 5a.	FERM domain-containing protein.	0.786
LOC109989160	LOC109981137	ENSLBEP00000026754	ENSLBEP00000022946	PDZ and LIM domain 5a.	G protein-coupled receptor kinase interacting ArfGAP 2b.	0.804
TGFB1I1	ENSLBEP00000030475	ENSLBEP00000029438	ENSLBEP00000030475	Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways.	Focal_AT domain-containing protein.	0.851
TGFB1I1	ENSLBEP00000030746	ENSLBEP00000029438	ENSLBEP00000030746	Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways.	FERM domain-containing protein.	0.786
TGFB1I1	LOC109981137	ENSLBEP00000029438	ENSLBEP00000022946	Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways.	G protein-coupled receptor kinase interacting ArfGAP 2b.	0.906