(6 nodes) Mixed, incl. PLC-gamma, N-terminal SH2 domain, and Platelet-derived growth factor receptor-like protein network (Labrus bergylta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	plcg2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1269 aa)
	LOC109981096	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (212 aa)
	ENSLBEP00000023570	Ig domain-containing protein. (289 aa)
	ENSLBEP00000023602	Protein kinase domain-containing protein. (170 aa)
	LOC109981175	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (251 aa)
	LOC110000323	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1313 aa)

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSLBEP00000023570	LOC109981096	ENSLBEP00000023570	ENSLBEP00000021415	Ig domain-containing protein.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.781
ENSLBEP00000023570	LOC109981175	ENSLBEP00000023570	ENSLBEP00000031144	Ig domain-containing protein.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.871
ENSLBEP00000023570	LOC110000323	ENSLBEP00000023570	ENSLBEP00000034458	Ig domain-containing protein.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.876
ENSLBEP00000023570	plcg2	ENSLBEP00000023570	ENSLBEP00000008405	Ig domain-containing protein.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.877
ENSLBEP00000023602	LOC109981096	ENSLBEP00000023602	ENSLBEP00000021415	Protein kinase domain-containing protein.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.781
ENSLBEP00000023602	LOC109981175	ENSLBEP00000023602	ENSLBEP00000031144	Protein kinase domain-containing protein.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.871
ENSLBEP00000023602	LOC110000323	ENSLBEP00000023602	ENSLBEP00000034458	Protein kinase domain-containing protein.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.876
ENSLBEP00000023602	plcg2	ENSLBEP00000023602	ENSLBEP00000008405	Protein kinase domain-containing protein.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.877
LOC109981096	ENSLBEP00000023570	ENSLBEP00000021415	ENSLBEP00000023570	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Ig domain-containing protein.	0.781
LOC109981096	ENSLBEP00000023602	ENSLBEP00000021415	ENSLBEP00000023602	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Protein kinase domain-containing protein.	0.781
LOC109981096	LOC109981175	ENSLBEP00000021415	ENSLBEP00000031144	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.455
LOC109981096	LOC110000323	ENSLBEP00000021415	ENSLBEP00000034458	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.569
LOC109981096	plcg2	ENSLBEP00000021415	ENSLBEP00000008405	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.569
LOC109981175	ENSLBEP00000023570	ENSLBEP00000031144	ENSLBEP00000023570	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Ig domain-containing protein.	0.871
LOC109981175	ENSLBEP00000023602	ENSLBEP00000031144	ENSLBEP00000023602	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Protein kinase domain-containing protein.	0.871
LOC109981175	LOC109981096	ENSLBEP00000031144	ENSLBEP00000021415	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.455
LOC109981175	LOC110000323	ENSLBEP00000031144	ENSLBEP00000034458	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.516
LOC109981175	plcg2	ENSLBEP00000031144	ENSLBEP00000008405	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.516
LOC110000323	ENSLBEP00000023570	ENSLBEP00000034458	ENSLBEP00000023570	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	Ig domain-containing protein.	0.876
LOC110000323	ENSLBEP00000023602	ENSLBEP00000034458	ENSLBEP00000023602	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	Protein kinase domain-containing protein.	0.876