STRINGSTRING
LOC110003678 LOC110003678 ENSLBEP00000011876 ENSLBEP00000011876 cd40lg cd40lg rnf8 rnf8 DCAF1 DCAF1 atm atm LOC109979207 LOC109979207 mlh1 mlh1 msh3 msh3 lig4 lig4 lef1 lef1 aicda aicda msh6 msh6 exosc3 exosc3 LOC109976602 LOC109976602 LOC110003486 LOC110003486 msh2 msh2 tcf7 tcf7 LOC109992673 LOC109992673 rag1 rag1 UNG UNG LOC109990949 LOC109990949 ENSLBEP00000000333 ENSLBEP00000000333 MSH2 MSH2 rag2 rag2 ENSLBEP00000004509 ENSLBEP00000004509 ercc1 ercc1 batf batf LOC109993446 LOC109993446
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC110003678Uncharacterized protein. (363 aa)
ENSLBEP00000011876Uncharacterized protein. (726 aa)
cd40lgCD40 ligand; Belongs to the tumor necrosis factor family. (238 aa)
rnf8E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (525 aa)
DCAF1DDB1 and CUL4 associated factor 1. (1312 aa)
atmNon-specific serine/threonine protein kinase. (3019 aa)
LOC109979207DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1148 aa)
mlh1MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli). (648 aa)
msh3MutS homolog 3 (E. coli); Component of the post-replicative DNA mismatch repair system (MMR). (1024 aa)
lig4DNA ligase. (827 aa)
lef1Lymphoid enhancer-binding factor 1. (379 aa)
aicdaActivation-induced cytidine deaminase. (215 aa)
msh6DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1382 aa)
exosc3Exosome component 3. (245 aa)
LOC109976602LisH domain-containing protein. (949 aa)
LOC110003486LisH domain-containing protein. (949 aa)
msh2DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (935 aa)
tcf7Transcription factor 7. (386 aa)
LOC109992673Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4073 aa)
rag1V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1066 aa)
UNGUracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. (279 aa)
LOC109990949Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family. (335 aa)
ENSLBEP00000000333Uncharacterized protein. (270 aa)
MSH2MutS homolog 2. (600 aa)
rag2Recombination activating gene 2. (533 aa)
ENSLBEP00000004509Chemokine (C-C motif) receptor 6b. (305 aa)
ercc1Excision repair cross-complementation group 1. (398 aa)
batfBasic leucine zipper transcription factor, ATF-like. (114 aa)
LOC109993446AAA domain-containing protein. (835 aa)
Your Current Organism:
Labrus bergylta
NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse
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