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LOC109976039 LOC109976039 LOC109981845 LOC109981845 ENSLBEP00000000081 ENSLBEP00000000081 ENSLBEP00000000247 ENSLBEP00000000247 LOC109981282 LOC109981282 mpc2 mpc2 pdhx pdhx elovl5 elovl5 mcee mcee LOC109984836 LOC109984836 LOC109983569 LOC109983569 LOC109983552 LOC109983552 aass aass ACLY ACLY LOC110000983 LOC110000983 LOC110000978 LOC110000978 LOC110001682 LOC110001682 dlat dlat ENSLBEP00000006820 ENSLBEP00000006820 nudt19 nudt19 LOC109997509 LOC109997509 GCDH GCDH ENSLBEP00000008996 ENSLBEP00000008996 ENSLBEP00000009082 ENSLBEP00000009082 ENSLBEP00000009124 ENSLBEP00000009124 ENSLBEP00000009586 ENSLBEP00000009586 LOC109990094 LOC109990094 mvd mvd acaca acaca LOC109984406 LOC109984406 LOC110006114 LOC110006114 acot8 acot8 gpam gpam ENSLBEP00000013527 ENSLBEP00000013527 nudt7 nudt7 LOC109997607 LOC109997607 LOC109989578 LOC109989578 LOC110004950 LOC110004950 LOC109994182 LOC109994182 ENSLBEP00000014291 ENSLBEP00000014291 mvk mvk acacb acacb nudt8 nudt8 mlycd mlycd LOC109979461 LOC109979461 LOC109977161 LOC109977161 LOC110004608 LOC110004608 acsl4 acsl4 LOC109975918 LOC109975918 tdo2 tdo2 ENSLBEP00000020261 ENSLBEP00000020261 LOC109984291 LOC109984291 acsl6 acsl6 elovl6 elovl6 acot9 acot9 LOC109993129 LOC109993129 elovl7 elovl7 hsd17b4 hsd17b4 LOC109996101 LOC109996101 acot11 acot11 acsl3 acsl3 LOC110002549 LOC110002549 elovl1 elovl1 LOC109991452 LOC109991452 ACOT7 ACOT7 LOC109998846 LOC109998846 LOC110003117 LOC110003117 LOC110002629 LOC110002629 LOC109990269 LOC109990269 LOC109984045 LOC109984045 ppcs ppcs acsl1 acsl1 fitm2 fitm2 pipox pipox LOC110000316 LOC110000316 suclg2 suclg2 pdhb pdhb LOC109991657 LOC109991657 LOC109997342 LOC109997342 oxsm oxsm DLST DLST ENSLBEP00000037482 ENSLBEP00000037482 aadat aadat acss1 acss1 LOC109992761 LOC109992761
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
LOC109976039Elongation of very long chain fatty acids protein 6; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degre [...] (270 aa)
LOC109981845Acyl-CoA synthetase long chain family member 5. (631 aa)
ENSLBEP00000000081BAAT_C domain-containing protein. (209 aa)
ENSLBEP00000000247Uncharacterized protein. (497 aa)
LOC109981282Dihydrolipoamide S-succinyltransferase. (446 aa)
mpc2Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (129 aa)
pdhxDihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (496 aa)
elovl5Elongation of very long chain fatty acids protein 5; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. May participate to the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involv [...] (294 aa)
mceeMethylmalonyl CoA epimerase. (173 aa)
LOC109984836Uncharacterized protein. (475 aa)
LOC109983569Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (390 aa)
LOC109983552Uncharacterized protein. (611 aa)
aassAminoadipate-semialdehyde synthase. (894 aa)
ACLYATP-citrate synthase; In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family. (1092 aa)
LOC110000983Uncharacterized protein. (428 aa)
LOC110000978Uncharacterized protein. (427 aa)
LOC110001682Acyl-CoA synthetase long chain family member 2. (716 aa)
dlatAcetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (640 aa)
ENSLBEP00000006820Acyl-CoA thioesterase 7. (215 aa)
nudt19Nudix (nucleoside diphosphate linked moiety X)-type motif 19. (473 aa)
LOC109997509Uncharacterized protein. (445 aa)
GCDHGlutaryl-CoA dehydrogenase b. (455 aa)
ENSLBEP00000008996Uncharacterized protein. (427 aa)
ENSLBEP00000009082Uncharacterized protein. (414 aa)
ENSLBEP00000009124BAAT_C domain-containing protein. (193 aa)
ENSLBEP00000009586Elongation of very long chain fatty acids protein. (226 aa)
LOC109990094Elongation of very long chain fatty acids protein 4; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that specifically elongates C24:0 and C26:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane [...] (305 aa)
mvdDiphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes. (402 aa)
acacaAcetyl-CoA carboxylase alpha. (2323 aa)
LOC109984406Elongation of very long chain fatty acids protein 4; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that specifically elongates C24:0 and C26:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane [...] (321 aa)
LOC1100061143-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (357 aa)
acot8Acyl-CoA thioesterase 8. (327 aa)
gpamGlycerol-3-phosphate acyltransferase 1, mitochondrial. (827 aa)
ENSLBEP00000013527Uncharacterized protein. (172 aa)
nudt7Nudix (nucleoside diphosphate linked moiety X)-type motif 7. (222 aa)
LOC109997607Elongation of very long chain fatty acids protein. (280 aa)
LOC109989578Glutaryl-CoA dehydrogenase a. (440 aa)
LOC110004950Phosphomevalonate kinase. (196 aa)
LOC109994182Acetyl-coenzyme A synthetase. (677 aa)
ENSLBEP00000014291Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. (71 aa)
mvkMevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (397 aa)
acacbAcetyl-CoA carboxylase beta. (2403 aa)
nudt8Nudix hydrolase domain-containing protein. (475 aa)
mlycdMalonyl-CoA decarboxylase. (504 aa)
LOC109979461Uncharacterized protein. (402 aa)
LOC109977161Uncharacterized protein. (416 aa)
LOC110004608Acetyl-coenzyme A synthetase. (673 aa)
acsl4Acyl-CoA synthetase long chain family member 4a. (712 aa)
LOC109975918Uncharacterized protein. (210 aa)
tdo2Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. (407 aa)
ENSLBEP00000020261ACAS_N domain-containing protein. (93 aa)
LOC109984291Acyl-CoA synthetase long chain family member 1b. (682 aa)
acsl6AMP-binding domain-containing protein. (722 aa)
elovl6Elongation of very long chain fatty acids protein 6; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degre [...] (269 aa)
acot9Acyl-CoA thioesterase 9, tandem duplicate 2. (474 aa)
LOC109993129Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (452 aa)
elovl7Elongation of very long chain fatty acids protein 7; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:3(n-3) acyl-CoAs and C18:3(n-6)-CoAs. Also active toward C20:4-, C18:0-, C18:1-, C18:2- and C16:0-CoAs, and weakly toward C20:0-CoA. Little or no activity toward C22:0-, C24:0 [...] (294 aa)
hsd17b4Hydroxysteroid (17-beta) dehydrogenase 4. (670 aa)
LOC109996101Elongation of very long chain fatty acids protein. (263 aa)
acot11Acyl-CoA thioesterase 11b. (635 aa)
acsl3AMP-binding domain-containing protein. (719 aa)
LOC110002549Elongation of very long chain fatty acids protein 6; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degre [...] (266 aa)
elovl1Elongation of very long chain fatty acids protein 1; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that [...] (319 aa)
LOC109991452Elongation of very long chain fatty acids protein 1; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that [...] (316 aa)
ACOT7Acyl-CoA thioesterase 7. (188 aa)
LOC109998846Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. (551 aa)
LOC110003117Phosphomevalonate kinase. (194 aa)
LOC110002629ATP-citrate synthase; In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family. (1120 aa)
LOC109990269Uncharacterized protein. (467 aa)
LOC109984045Acyl-CoA synthetase long chain family member 3b. (711 aa)
ppcsPhosphopantothenoylcysteine synthetase. (353 aa)
acsl1Acyl-CoA synthetase long chain family member 1a. (697 aa)
fitm2Fat storage inducing transmembrane protein 2. (260 aa)
pipoxPipecolic acid oxidase. (388 aa)
LOC110000316Acetyl-coenzyme A synthetase. (638 aa)
suclg2Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (431 aa)
pdhbPyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (378 aa)
LOC109991657Uncharacterized protein. (426 aa)
LOC109997342Uncharacterized protein. (621 aa)
oxsm3-oxoacyl-[acyl-carrier-protein] synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (443 aa)
DLSTDihydrolipoamide S-succinyltransferase. (449 aa)
ENSLBEP00000037482annotation not available (357 aa)
aadatAminoadipate aminotransferase. (403 aa)
acss1Acetyl-coenzyme A synthetase. (696 aa)
LOC109992761Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. (517 aa)
Your Current Organism:
Labrus bergylta
NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse
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