(85 nodes) Endoplasmic reticulum organization network (Labrus bergylta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC110002571	Extended synaptotagmin-like protein 2b. (837 aa)
	pcnx1	Pecanex 1. (2062 aa)
	LOC109982699	Protein transport protein sec16; Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus. (952 aa)
	LOC109975395	Receptor expression-enhancing protein. (216 aa)
	get4	Guided entry of tail-anchored proteins factor 4. (323 aa)
	LOC110000349	ER membrane protein complex subunit 10. (257 aa)
	LOC109985293	BCL2 interacting protein 1b. (230 aa)
	lrrk2	Leucine-rich repeat kinase 2. (2422 aa)
	LOC109992874	Zinc_ribbon_10 domain-containing protein. (457 aa)
	emc8	ER membrane protein complex subunit 8. (204 aa)
	LOC109995215	GRAM domain-containing protein. (318 aa)
	emc2	ER membrane protein complex subunit 2. (297 aa)
	LOC110005592	Uncharacterized protein. (183 aa)
	eif2ak3	Eukaryotic translation initiation factor 2-alpha kinase 3. (1036 aa)
	tmem170a	Transmembrane protein 170A. (138 aa)
	ccdc47	Coiled-coil domain containing 47. (341 aa)
	LOC110002099	Ubiquitin-like domain-containing protein. (156 aa)
	LOC109993507	Receptor expression-enhancing protein. (257 aa)
	pcnx3	Pecanex 3. (2243 aa)
	emc1	ER membrane protein complex subunit 1. (962 aa)
	LOC109996898	Jagunal homolog 1a. (183 aa)
	LOC109995857	Uncharacterized protein. (259 aa)
	ENSLBEP00000008790	Uncharacterized protein. (161 aa)
	LOC109985454	Atlastin 3. (511 aa)
	LOC109992982	SEC31 homolog B, COPII coat complex component. (1133 aa)
	ENSLBEP00000012908	Uncharacterized protein. (69 aa)
	LOC110004517	ER membrane protein complex subunit 3; Belongs to the EMC3 family. (261 aa)
	ENSLBEP00000013502	Ubiquitin-like domain-containing protein. (149 aa)
	LOC109978209	ER membrane protein complex subunit 10. (257 aa)
	emc3	ER membrane protein complex subunit 3; Belongs to the EMC3 family. (261 aa)
	get3	ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...] (341 aa)
	cunhxorf56	Zgc:103697. (225 aa)
	zfyve27	Zinc finger, FYVE domain containing 27. (344 aa)
	ENSLBEP00000015241	Extended synaptotagmin-like protein 1a. (756 aa)
	lpcat3	Lysophosphatidylcholine acyltransferase 3; Belongs to the membrane-bound acyltransferase family. (463 aa)
	LOC109986722	Lectin, mannose-binding 2. (384 aa)
	get1	Guided entry of tail-anchored proteins factor 1. (170 aa)
	bag6	BCL2 associated athanogene 6, like. (1138 aa)
	wdr83os	WD repeat domain 83 opposite strand. (106 aa)
	emc7	ER membrane protein complex subunit 7. (240 aa)
	ENSLBEP00000018377	Uncharacterized protein. (199 aa)
	tmed2	Transmembrane p24 trafficking protein 2. (235 aa)
	LOC109990189	Jagunal homolog 1b. (196 aa)
	LOC110004651	Reticulophagy regulator 1. (329 aa)
	tram1	Translocating chain-associated membrane protein; Belongs to the TRAM family. (370 aa)
	emc6	ER membrane protein complex subunit 6. (110 aa)
	tmem33	Transmembrane protein 33. (248 aa)
	mmgt1	Membrane magnesium transporter 1. (198 aa)
	LOC109984327	Limb and neural patterns a. (405 aa)
	LOC109992030	BCL2 associated athanogene 6. (1142 aa)
	LOC109996597	Lectin, mannose-binding 2-like a. (361 aa)
	atl1	Atlastin GTPase 1. (588 aa)
	lman1	Lectin, mannose-binding, 1. (518 aa)
	emc9	ER membrane protein complex subunit 9. (205 aa)
	gramd2a	GRAM domain containing 2A. (362 aa)
	ENSLBEP00000023797	Extended synaptotagmin-like protein 1b. (1058 aa)
	LOC110005206	L-type lectin-like domain-containing protein. (381 aa)
	ENSLBEP00000038833	Receptor expression-enhancing protein. (169 aa)
	LOC110001522	Valosin containing protein (p97)/p47 complex interacting protein 1. (1140 aa)
	LOC109988724	Si:ch211-1o7.3. (584 aa)
	ENSLBEP00000037432	Shootin 1. (472 aa)
	sec16a	Protein transport protein sec16; Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus. (2370 aa)
	sec31a	SEC31 homolog A, COPII coat complex component. (1453 aa)
	camlg	Calcium signal-modulating cyclophilin ligand; Likely involved in the mobilization of calcium as a result of the TCR/CD3 complex interaction. Binds to cyclophilin B. (291 aa)
	ENSLBEP00000036665	Lectin, mannose-binding 2-like b. (293 aa)
	reep3	Receptor expression-enhancing protein. (262 aa)
	ENSLBEP00000035051	Extended synaptotagmin-like protein 2a. (585 aa)
	LOC109992229	Extended synaptotagmin-like protein 3. (848 aa)
	retreg2	Reticulophagy regulator family member 2. (603 aa)
	polr2m	RNA polymerase II subunit M. (349 aa)
	LOC109995599	Receptor expression-enhancing protein. (192 aa)
	VCPIP1	Valosin containing protein interacting protein 1. (1150 aa)
	LOC110001933	SMP-LTD domain-containing protein. (249 aa)
	pcnx4	Pecanex 4. (1216 aa)
	bnip1	BCL2 interacting protein 1a. (266 aa)
	ENSLBEP00000029506	Reticulophagy regulator 1. (268 aa)
	emc4	ER membrane protein complex subunit 4; Belongs to the EMC4 family. (190 aa)
	sptssb	Serine palmitoyltransferase, small subunit B. (80 aa)
	LOC110005344	Receptor expression-enhancing protein. (221 aa)
	ENSLBEP00000028450	Receptor expression-enhancing protein. (204 aa)
	atl2	Atlastin GTPase 2. (613 aa)
	ENSLBEP00000026579	Uncharacterized protein. (249 aa)
	pcnx2	Pecanex 2. (2141 aa)
	tram2	Translocating chain-associated membrane protein; Belongs to the TRAM family. (369 aa)
	LOC109989162	Translocating chain-associated membrane protein; Belongs to the TRAM family. (371 aa)

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSLBEP00000008790	LOC109978209	ENSLBEP00000008790	ENSLBEP00000013914	Uncharacterized protein.	ER membrane protein complex subunit 10.	0.879
ENSLBEP00000008790	LOC110000349	ENSLBEP00000008790	ENSLBEP00000001374	Uncharacterized protein.	ER membrane protein complex subunit 10.	0.879
ENSLBEP00000008790	ccdc47	ENSLBEP00000008790	ENSLBEP00000005782	Uncharacterized protein.	Coiled-coil domain containing 47.	0.445
ENSLBEP00000008790	emc1	ENSLBEP00000008790	ENSLBEP00000007419	Uncharacterized protein.	ER membrane protein complex subunit 1.	0.943
ENSLBEP00000008790	emc2	ENSLBEP00000008790	ENSLBEP00000005195	Uncharacterized protein.	ER membrane protein complex subunit 2.	0.957
ENSLBEP00000008790	emc4	ENSLBEP00000008790	ENSLBEP00000029261	Uncharacterized protein.	ER membrane protein complex subunit 4; Belongs to the EMC4 family.	0.964
ENSLBEP00000008790	emc6	ENSLBEP00000008790	ENSLBEP00000021278	Uncharacterized protein.	ER membrane protein complex subunit 6.	0.947
ENSLBEP00000008790	emc7	ENSLBEP00000008790	ENSLBEP00000018232	Uncharacterized protein.	ER membrane protein complex subunit 7.	0.948
ENSLBEP00000008790	emc8	ENSLBEP00000008790	ENSLBEP00000003701	Uncharacterized protein.	ER membrane protein complex subunit 8.	0.934
ENSLBEP00000008790	emc9	ENSLBEP00000008790	ENSLBEP00000023083	Uncharacterized protein.	ER membrane protein complex subunit 9.	0.850
ENSLBEP00000008790	get1	ENSLBEP00000008790	ENSLBEP00000016304	Uncharacterized protein.	Guided entry of tail-anchored proteins factor 1.	0.474
ENSLBEP00000008790	get3	ENSLBEP00000008790	ENSLBEP00000014639	Uncharacterized protein.	ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]	0.475
ENSLBEP00000008790	lman1	ENSLBEP00000008790	ENSLBEP00000022770	Uncharacterized protein.	Lectin, mannose-binding, 1.	0.664
ENSLBEP00000008790	mmgt1	ENSLBEP00000008790	ENSLBEP00000021523	Uncharacterized protein.	Membrane magnesium transporter 1.	0.937
ENSLBEP00000012908	ENSLBEP00000018377	ENSLBEP00000012908	ENSLBEP00000018377	Uncharacterized protein.	Uncharacterized protein.	0.870
ENSLBEP00000012908	ENSLBEP00000026579	ENSLBEP00000012908	ENSLBEP00000026579	Uncharacterized protein.	Uncharacterized protein.	0.870
ENSLBEP00000012908	LOC109982699	ENSLBEP00000012908	ENSLBEP00000000851	Uncharacterized protein.	Protein transport protein sec16; Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus.	0.904
ENSLBEP00000012908	LOC109992982	ENSLBEP00000012908	ENSLBEP00000011542	Uncharacterized protein.	SEC31 homolog B, COPII coat complex component.	0.847
ENSLBEP00000012908	lman1	ENSLBEP00000012908	ENSLBEP00000022770	Uncharacterized protein.	Lectin, mannose-binding, 1.	0.795
ENSLBEP00000012908	sec16a	ENSLBEP00000012908	ENSLBEP00000037252	Uncharacterized protein.	Protein transport protein sec16; Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus.	0.904