(110 nodes) Response to mechanical stimulus network (Labrus bergylta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC109993950	Transmembrane protein 132E. (524 aa)
	ENSLBEP00000001176	Polycystic kidney disease 1b. (3080 aa)
	ptk2b	Protein tyrosine kinase 2 beta, b; Belongs to the protein kinase superfamily. Tyr protein kinase family. (993 aa)
	ENSLBEP00000002089	Stereocilin 1. (1481 aa)
	gclc	Glutamate-cysteine ligase, catalytic subunit. (630 aa)
	LOC109989420	Whirlin b. (840 aa)
	KCNK4	Potassium two pore domain channel subfamily K member 4; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (475 aa)
	slitrk6	SLIT and NTRK-like family, member 6. (843 aa)
	LOC109995768	Uncharacterized protein. (748 aa)
	LOC109981905	Uncharacterized protein. (315 aa)
	LOC109997975	Bradykinin receptor B1; Belongs to the G-protein coupled receptor 1 family. (372 aa)
	LOC109995799	Uncharacterized protein; Belongs to the peptidase C14A family. (489 aa)
	LOC109995221	Uncharacterized protein. (417 aa)
	LOC109995961	Uncharacterized protein; Belongs to the peptidase C14A family. (369 aa)
	dlx5	Distal-less homeobox 5a. (285 aa)
	tcap	Titin-cap (telethonin). (180 aa)
	LOC109997947	IRF tryptophan pentad repeat domain-containing protein. (255 aa)
	LOC109983659	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a. (308 aa)
	LOC109990003	Si:dkey-71b5.7. (1135 aa)
	ENSLBEP00000007524	WD_REPEATS_REGION domain-containing protein. (345 aa)
	ENSLBEP00000007593	TBC1 domain family, member 31. (479 aa)
	hpn	Hepsin; Belongs to the peptidase S1 family. (427 aa)
	pjvk	Pejvakin. (392 aa)
	LOC109985423	Potassium channel, subfamily K, member 4a; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (636 aa)
	ENSLBEP00000008816	Uncharacterized protein. (586 aa)
	ENSLBEP00000008874	Uncharacterized protein. (300 aa)
	ENSLBEP00000008892	Uncharacterized protein. (305 aa)
	LOC110002853	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (574 aa)
	fosl1	FOS-like antigen 1a. (344 aa)
	ENSLBEP00000009944	PDZ domain containing 7a. (872 aa)
	LOC109999319	Uncharacterized protein. (923 aa)
	ENSLBEP00000010472	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (320 aa)
	xpc	Xeroderma pigmentosum, complementation group C. (930 aa)
	tmem120a	Transmembrane protein 120A. (347 aa)
	LOC109990637	Junction plakoglobin a. (705 aa)
	LOC109996406	ADP-ribosylation factor 2b. (1011 aa)
	bnip3	BCL2 interacting protein 3. (226 aa)
	kiaa0319l	Si:ch211-193k19.1. (978 aa)
	pkd1	Polycystic kidney disease 1a. (4615 aa)
	LOC110006230	Prostaglandin E receptor 4 (subtype EP4) c; Belongs to the G-protein coupled receptor 1 family. (484 aa)
	LOC109975774	Transmembrane channel-like protein. (914 aa)
	ENSLBEP00000014949	Uncharacterized protein. (181 aa)
	htt	Huntingtin. (3002 aa)
	LOC109996990	CD40 molecule, TNF receptor superfamily member 5. (308 aa)
	LOC109995405	Uncharacterized protein. (333 aa)
	get1	Guided entry of tail-anchored proteins factor 1. (170 aa)
	LOC109989552	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (282 aa)
	bag3	BCL2 associated athanogene 3. (542 aa)
	LOC109999425	Polycystic kidney disease 2-like 1. (783 aa)
	il1b	Interleukin-1. (251 aa)
	ENSLBEP00000017636	Uncharacterized protein. (108 aa)
	PIEZO2	Piezo-type mechanosensitive ion channel component. (2440 aa)
	LOC109983245	Otoferlin a. (2032 aa)
	LOC109993661	Caspase 2, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (491 aa)
	piezo1	Piezo-type mechanosensitive ion channel component. (2343 aa)
	trpa1	Transient receptor potential cation channel, subfamily A, member 1b; Belongs to the transient receptor (TC 1.A.4) family. (1119 aa)
	LOC109975928	Uncharacterized protein; Belongs to the peptidase C14A family. (242 aa)
	LOC109975131	Uncharacterized protein. (303 aa)
	chek1	Checkpoint kinase 1. (504 aa)
	IRF1	Interferon regulatory factor. (291 aa)
	bad	BCL2 associated agonist of cell death b. (221 aa)
	pkd2	Polycystic kidney disease 2. (903 aa)
	ucn	Urotensin 1. (121 aa)
	csrp3	Cysteine and glycine-rich protein 3 (cardiac LIM protein). (193 aa)
	lrp11	Low density lipoprotein receptor-related protein 11. (496 aa)
	ENSLBEP00000022374	Uncharacterized protein. (194 aa)
	LOC109984320	Caspase 10, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (540 aa)
	mkks	McKusick-Kaufman syndrome. (567 aa)
	serpine2	Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2; Belongs to the serpin family. (397 aa)
	LOC109981632	Prostaglandin E receptor 4 (subtype EP4) a; Belongs to the G-protein coupled receptor 1 family. (451 aa)
	ENSLBEP00000024000	Transmembrane channel-like protein. (824 aa)
	whrn	Whirlin a. (984 aa)
	p2rx3	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (390 aa)
	LOC109987355	ZP domain-containing protein. (630 aa)
	LOC109982249	Protein tyrosine phosphatase receptor type Q. (2180 aa)
	LOC109999589	Aquaporin 1a (Colton blood group), tandem duplicate 1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (261 aa)
	ENSLBEP00000026765	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (180 aa)
	LOC109999587	Aquaporin 1a (Colton blood group), tandem duplicate 2; Belongs to the MIP/aquaporin (TC 1.A.8) family. (264 aa)
	LOC109984366	Toll-like receptor 7; Belongs to the Toll-like receptor family. (1053 aa)
	TLR8	Toll like receptor 8. (1022 aa)
	ENSLBEP00000028076	Piezo_RRas_bdg domain-containing protein. (589 aa)
	ENSLBEP00000028176	PIEZO domain-containing protein. (1216 aa)
	fer1l6	Fer-1 like family member 6. (1740 aa)
	LOC109988511	JunE proto-oncogene, AP-1 transcription factor subunit. (344 aa)
	phf24	PHD finger protein 24. (414 aa)
	LOC109998905	Uncharacterized protein. (204 aa)
	LOC109998896	Zgc:153993. (205 aa)
	TMC1	Transmembrane channel-like protein. (852 aa)
	LOC109983373	Transmembrane channel-like protein. (900 aa)
	fadd	Uncharacterized protein. (192 aa)
	nfkbia	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b. (318 aa)
	LOC110005611	Uncharacterized protein; Belongs to the potassium channel family. (724 aa)
	ENSLBEP00000030475	Focal_AT domain-containing protein. (115 aa)
	ENSLBEP00000030539	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (524 aa)
	ENSLBEP00000030697	FERM_N_2 domain-containing protein. (103 aa)
	LOC109997856	Mitogen-activated protein kinase kinase kinase 14a. (855 aa)
	LOC109988649	Uncharacterized protein. (627 aa)
	LOC109984442	Prostaglandin E receptor 4 (subtype EP4) b. (447 aa)
	LOC109993297	F11 receptor, tandem duplicate 1. (319 aa)
	LOC109994487	Uncharacterized protein. (1916 aa)
	ptn	Pleiotrophin. (149 aa)
	LOC109990924	Potassium voltage-gated channel, KQT-like subfamily, member 1.1; Belongs to the potassium channel family. (586 aa)
	LOC109984498	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1005 aa)
	LOC109975490	Uncharacterized protein. (1756 aa)
	slc26a5	Solute carrier family 26 member 5. (748 aa)
	map2k4	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (432 aa)
	tmem150c	Transmembrane protein 150C. (246 aa)
	LOC109989848	Transmembrane O-methyltransferase. (259 aa)
	PDZD7	PDZ domain containing 7. (885 aa)
	LOC109998489	Zgc:73226. (177 aa)

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSLBEP00000001176	LOC109975490	ENSLBEP00000001176	ENSLBEP00000035606	Polycystic kidney disease 1b.	Uncharacterized protein.	0.780
ENSLBEP00000001176	LOC109994487	ENSLBEP00000001176	ENSLBEP00000034077	Polycystic kidney disease 1b.	Uncharacterized protein.	0.780
ENSLBEP00000001176	LOC109999425	ENSLBEP00000001176	ENSLBEP00000016825	Polycystic kidney disease 1b.	Polycystic kidney disease 2-like 1.	0.944
ENSLBEP00000001176	pkd2	ENSLBEP00000001176	ENSLBEP00000021618	Polycystic kidney disease 1b.	Polycystic kidney disease 2.	0.945
ENSLBEP00000002089	ENSLBEP00000009944	ENSLBEP00000002089	ENSLBEP00000009944	Stereocilin 1.	PDZ domain containing 7a.	0.491
ENSLBEP00000002089	LOC109983659	ENSLBEP00000002089	ENSLBEP00000007019	Stereocilin 1.	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a.	0.434
ENSLBEP00000002089	LOC109989420	ENSLBEP00000002089	ENSLBEP00000003111	Stereocilin 1.	Whirlin b.	0.497
ENSLBEP00000002089	PDZD7	ENSLBEP00000002089	ENSLBEP00000037761	Stereocilin 1.	PDZ domain containing 7.	0.491
ENSLBEP00000002089	nfkbia	ENSLBEP00000002089	ENSLBEP00000028970	Stereocilin 1.	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b.	0.434
ENSLBEP00000002089	pjvk	ENSLBEP00000002089	ENSLBEP00000008415	Stereocilin 1.	Pejvakin.	0.465
ENSLBEP00000002089	slitrk6	ENSLBEP00000002089	ENSLBEP00000004134	Stereocilin 1.	SLIT and NTRK-like family, member 6.	0.453
ENSLBEP00000002089	whrn	ENSLBEP00000002089	ENSLBEP00000025306	Stereocilin 1.	Whirlin a.	0.497
ENSLBEP00000007524	ENSLBEP00000007593	ENSLBEP00000007524	ENSLBEP00000007593	WD_REPEATS_REGION domain-containing protein.	TBC1 domain family, member 31.	0.927
ENSLBEP00000007593	ENSLBEP00000007524	ENSLBEP00000007593	ENSLBEP00000007524	TBC1 domain family, member 31.	WD_REPEATS_REGION domain-containing protein.	0.927
ENSLBEP00000008816	ENSLBEP00000008874	ENSLBEP00000008816	ENSLBEP00000008874	Uncharacterized protein.	Uncharacterized protein.	0.923
ENSLBEP00000008816	ENSLBEP00000028176	ENSLBEP00000008816	ENSLBEP00000028176	Uncharacterized protein.	PIEZO domain-containing protein.	0.900
ENSLBEP00000008874	ENSLBEP00000008816	ENSLBEP00000008874	ENSLBEP00000008816	Uncharacterized protein.	Uncharacterized protein.	0.923
ENSLBEP00000008874	ENSLBEP00000028076	ENSLBEP00000008874	ENSLBEP00000028076	Uncharacterized protein.	Piezo_RRas_bdg domain-containing protein.	0.948
ENSLBEP00000008892	LOC109975131	ENSLBEP00000008892	ENSLBEP00000020348	Uncharacterized protein.	Uncharacterized protein.	0.937
ENSLBEP00000008892	LOC109975928	ENSLBEP00000008892	ENSLBEP00000019952	Uncharacterized protein.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.586