(53 nodes) Regulation of phosphatase activity network (Labrus bergylta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC109998746	Cardiomyopathy associated 5. (1605 aa)
	cdk5rap3	CDK5 regulatory subunit associated protein 3. (477 aa)
	PPP1R1B	Protein phosphatase 1 regulatory inhibitor subunit 1B. (170 aa)
	styxl1	Serine/threonine/tyrosine interacting-like 1. (295 aa)
	ENSLBEP00000010675	Uncharacterized protein. (243 aa)
	uri1	URI1 prefoldin like chaperone. (501 aa)
	LOC110001596	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (215 aa)
	LOC109985425	Transforming growth factor beta; Belongs to the TGF-beta family. (421 aa)
	LOC109986627	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (215 aa)
	tiprl	TIP41, TOR signaling pathway regulator-like (S. cerevisiae). (324 aa)
	LOC109998617	Si:ch211-129c21.1; Belongs to the semaphorin family. (810 aa)
	LOC109983128	Protein phosphatase 1, regulatory (inhibitor) subunit 1B. (142 aa)
	LOC109981103	Angiotensin II receptor, type 2; Belongs to the G-protein coupled receptor 1 family. (416 aa)
	tgfb2	Transforming growth factor, beta 2. (275 aa)
	SEMA4D	Semaphorin 4D; Belongs to the semaphorin family. (888 aa)
	LOC110003138	ANK_REP_REGION domain-containing protein. (746 aa)
	LOC109998849	Membrane associated guanylate kinase, WW and PDZ domain containing 2a. (1316 aa)
	LOC109982179	Protein phosphatase 6, regulatory subunit 2b. (925 aa)
	LOC109985666	TSC complex subunit 1b. (1297 aa)
	rock1	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1367 aa)
	LOC110002615	Uncharacterized protein. (1201 aa)
	LOC109976804	Calcineurin-like EF-hand protein 1. (195 aa)
	ppp6r3	Protein phosphatase 6, regulatory subunit 3. (937 aa)
	LOC109995781	PPP1R35_C domain-containing protein. (300 aa)
	LOC109986022	Protein phosphatase 1, regulatory subunit 15B. (568 aa)
	mtmr9	Myotubularin related protein 9. (549 aa)
	LOC109984042	Semaphorin 4e; Belongs to the semaphorin family. (791 aa)
	LOC109985242	Uncharacterized protein. (416 aa)
	bag4	BCL2 associated athanogene 4. (388 aa)
	ppp1r12a	Protein phosphatase 1 regulatory subunit. (990 aa)
	ppp1r36	Uncharacterized protein. (392 aa)
	ptpa	Serine/threonine-protein phosphatase 2A activator; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. (324 aa)
	rock2	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1378 aa)
	ENSLBEP00000027466	PDZ domain-containing protein. (150 aa)
	htt	Huntingtin. (3002 aa)
	ppp1r11	Protein phosphatase 1, regulatory (inhibitor) subunit 11. (123 aa)
	hsp90b1	Heat shock protein 90, beta (grp94), member 1. (785 aa)
	LOC109986726	Peroxisome proliferator-activated receptor gamma, coactivator 1 beta. (736 aa)
	LOC109998157	Uncharacterized protein; Belongs to the protein kinase superfamily. (449 aa)
	LOC109992449	Zgc:154055. (554 aa)
	CHP1	Calcineurin B homologous protein 1. (195 aa)
	LOC109995578	Receptor-interacting serine-threonine kinase 3. (494 aa)
	vrk3	VRK serine/threonine kinase 3. (484 aa)
	ppp4r4	Protein phosphatase 4, regulatory subunit 4. (652 aa)
	ppp1r2	Protein phosphatase 1, regulatory (inhibitor) subunit 2. (209 aa)
	bod1l1	Uncharacterized protein. (1598 aa)
	LOC109997305	Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase. (742 aa)
	LOC110001975	Calcineurin-like EF-hand protein 2. (193 aa)
	ppp6r2	Protein phosphatase 6, regulatory subunit 2a. (913 aa)
	ptprc	Protein tyrosine phosphatase receptor type C. (1151 aa)
	LOC110002047	PDZ domain-containing protein. (164 aa)
	ENSLBEP00000038766	Transforming growth factor, beta 2. (141 aa)
	mastl	Microtubule associated serine/threonine kinase-like. (797 aa)

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSLBEP00000010675	LOC109995578	ENSLBEP00000010675	ENSLBEP00000029624	Uncharacterized protein.	Receptor-interacting serine-threonine kinase 3.	0.567
ENSLBEP00000010675	LOC109998157	ENSLBEP00000010675	ENSLBEP00000016647	Uncharacterized protein.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.567
ENSLBEP00000010675	hsp90b1	ENSLBEP00000010675	ENSLBEP00000015377	Uncharacterized protein.	Heat shock protein 90, beta (grp94), member 1.	0.803
ENSLBEP00000010675	rock1	ENSLBEP00000010675	ENSLBEP00000027068	Uncharacterized protein.	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	0.407
ENSLBEP00000010675	rock2	ENSLBEP00000010675	ENSLBEP00000027555	Uncharacterized protein.	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	0.407
ENSLBEP00000027466	LOC110002615	ENSLBEP00000027466	ENSLBEP00000027222	PDZ domain-containing protein.	Uncharacterized protein.	0.579
ENSLBEP00000038766	LOC109985425	ENSLBEP00000038766	ENSLBEP00000008551	Transforming growth factor, beta 2.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.834
ENSLBEP00000038766	tgfb2	ENSLBEP00000038766	ENSLBEP00000022373	Transforming growth factor, beta 2.	Transforming growth factor, beta 2.	0.927
LOC109984042	ptprc	ENSLBEP00000001761	ENSLBEP00000036424	Semaphorin 4e; Belongs to the semaphorin family.	Protein tyrosine phosphatase receptor type C.	0.778
LOC109984042	rock1	ENSLBEP00000001761	ENSLBEP00000027068	Semaphorin 4e; Belongs to the semaphorin family.	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	0.568
LOC109984042	rock2	ENSLBEP00000001761	ENSLBEP00000027555	Semaphorin 4e; Belongs to the semaphorin family.	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	0.568
LOC109985425	ENSLBEP00000038766	ENSLBEP00000008551	ENSLBEP00000038766	Transforming growth factor beta; Belongs to the TGF-beta family.	Transforming growth factor, beta 2.	0.834
LOC109985425	tgfb2	ENSLBEP00000008551	ENSLBEP00000022373	Transforming growth factor beta; Belongs to the TGF-beta family.	Transforming growth factor, beta 2.	0.833
LOC109985666	LOC109995578	ENSLBEP00000026751	ENSLBEP00000029624	TSC complex subunit 1b.	Receptor-interacting serine-threonine kinase 3.	0.567
LOC109985666	LOC109998157	ENSLBEP00000026751	ENSLBEP00000016647	TSC complex subunit 1b.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.567
LOC109985666	hsp90b1	ENSLBEP00000026751	ENSLBEP00000015377	TSC complex subunit 1b.	Heat shock protein 90, beta (grp94), member 1.	0.803
LOC109985666	rock1	ENSLBEP00000026751	ENSLBEP00000027068	TSC complex subunit 1b.	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	0.407
LOC109985666	rock2	ENSLBEP00000026751	ENSLBEP00000027555	TSC complex subunit 1b.	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	0.407
LOC109986627	styxl1	ENSLBEP00000008421	ENSLBEP00000011193	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.	Serine/threonine/tyrosine interacting-like 1.	0.400
LOC109995578	ENSLBEP00000010675	ENSLBEP00000029624	ENSLBEP00000010675	Receptor-interacting serine-threonine kinase 3.	Uncharacterized protein.	0.567