(91 nodes) Negative regulation of neuron projection development network (Labrus bergylta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC109999320	Sema domain-containing protein. (1092 aa)
	bicdl1	BICD family like cargo adaptor 1. (546 aa)
	ENSLBEP00000001605	Uncharacterized protein. (817 aa)
	LOC109984042	Semaphorin 4e; Belongs to the semaphorin family. (791 aa)
	cdk5	Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
	LOC109984046	Sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6Ba; Belongs to the semaphorin family. (894 aa)
	LOC109995732	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
	LOC109996841	Disco-interacting protein 2 homolog A. (1319 aa)
	LOC109984039	Uncharacterized protein. (1208 aa)
	lrrk2	Leucine-rich repeat kinase 2. (2422 aa)
	LOC109991736	Reticulon 4 receptor-like 1a. (455 aa)
	LOC109984777	Spartin b. (600 aa)
	LOC109981886	Dickkopf WNT signaling pathway inhibitor 1a. (253 aa)
	LOC110000419	Deoxyguanosine kinase. (300 aa)
	bag5	BCL2 associated athanogene 5. (504 aa)
	efna1	Ephrin-A1b; Belongs to the ephrin family. (234 aa)
	LOC110001021	Sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6E; Belongs to the semaphorin family. (652 aa)
	LOC109998617	Si:ch211-129c21.1; Belongs to the semaphorin family. (810 aa)
	sema6d	Sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D, like; Belongs to the semaphorin family. (1108 aa)
	LOC109996372	RAB29, member RAS oncogene family. (205 aa)
	LOC109999299	Sema domain-containing protein; Belongs to the semaphorin family. (837 aa)
	sema5b	Sema domain-containing protein. (1015 aa)
	sema4b	Sema domain-containing protein; Belongs to the semaphorin family. (837 aa)
	LOC109993557	Interferon-related developmental regulator 2. (446 aa)
	LOC109994658	Uncharacterized protein; Belongs to the semaphorin family. (897 aa)
	kremen1	Kringle containing transmembrane protein 1. (462 aa)
	ENSLBEP00000010675	Uncharacterized protein. (243 aa)
	ulk2	Unc-51 like autophagy activating kinase 2. (1030 aa)
	LOC110004906	Si:dkey-49n23.1; Belongs to the semaphorin family. (361 aa)
	rtn4r	Reticulon 4 receptor. (466 aa)
	ulk1	Unc-51 like autophagy activating kinase 1. (1019 aa)
	ITM2C	Integral membrane protein 2C. (259 aa)
	LOC109993644	Sema domain-containing protein; Belongs to the semaphorin family. (812 aa)
	LOC109992406	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
	ifrd1	Interferon-related developmental regulator 1. (428 aa)
	LOC109988379	FAT atypical cadherin 3b. (4220 aa)
	sema5a	Sema domain-containing protein. (1078 aa)
	LOC109994790	Disco-interacting protein 2 homolog Ba. (1591 aa)
	LOC109998214	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Aa; Belongs to the semaphorin family. (865 aa)
	LOC110003002	Uncharacterized protein; Belongs to the semaphorin family. (592 aa)
	sema7a	Semaphorin 7A; Belongs to the semaphorin family. (606 aa)
	dab2	DAB adaptor protein 2. (764 aa)
	sema6a	Semaphorin 6A; Belongs to the semaphorin family. (956 aa)
	LOC109990231	Uncharacterized protein. (251 aa)
	LOC110001812	Sema domain-containing protein; Belongs to the semaphorin family. (810 aa)
	LOC109975219	Uncharacterized protein. (251 aa)
	LOC109994269	Disco-interacting protein 2 homolog Cb. (1486 aa)
	LOC109991426	Integral membrane protein 2Cb. (256 aa)
	LOC109975235	Sema domain-containing protein; Belongs to the semaphorin family. (465 aa)
	rufy3	RUN and FYVE domain containing 3. (647 aa)
	epha4	Eph receptor A4, like. (989 aa)
	stmn2	Stathmin; Belongs to the stathmin family. (179 aa)
	SEMA4D	Semaphorin 4D; Belongs to the semaphorin family. (888 aa)
	RAB29	Ras-related protein Rab-7L1-like. (205 aa)
	LOC109983903	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fb; Belongs to the semaphorin family. (701 aa)
	LOC109992490	Disco-interacting protein 2 homolog Bb. (1280 aa)
	UBE3A	Ubiquitin protein ligase E3A. (789 aa)
	LOC109982722	Sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6Bb; Belongs to the semaphorin family. (766 aa)
	LOC110003865	Uncharacterized protein; Belongs to the semaphorin family. (619 aa)
	LOC110002606	Si:ch211-113g11.6; Belongs to the semaphorin family. (488 aa)
	LOC109985666	TSC complex subunit 1b. (1297 aa)
	minar1	Membrane integral NOTCH2 associated receptor 1. (910 aa)
	LOC110004756	Si:ch73-40a2.1. (833 aa)
	sema3g	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3bl; Belongs to the semaphorin family. (788 aa)
	LOC109985090	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B; Belongs to the semaphorin family. (813 aa)
	lpar1	Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (353 aa)
	LOC109980617	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fa; Belongs to the semaphorin family. (789 aa)
	ENSLBEP00000028296	Sialidase 4. (464 aa)
	LOC109999978	Reticulon 4 receptor-like 1b. (452 aa)
	LOC109986327	Progestin and adipoQ receptor family member IIIb. (315 aa)
	LOC109997837	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D; Belongs to the semaphorin family. (597 aa)
	LOC109997833	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Ab; Belongs to the semaphorin family. (803 aa)
	sema3e	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E; Belongs to the semaphorin family. (790 aa)
	LOC110002701	Sema domain-containing protein. (253 aa)
	LOC109994993	Stathmin; Belongs to the stathmin family. (179 aa)
	snapin	SNAP associated protein. (152 aa)
	sema4c	Uncharacterized protein; Belongs to the semaphorin family. (845 aa)
	LOC109983354	Unc-51 like autophagy activating kinase 1a. (917 aa)
	LOC109982581	Ubiquitin protein ligase E3A. (827 aa)
	sema3c	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C; Belongs to the semaphorin family. (766 aa)
	LOC109989813	Reticulon 4 receptor-like 2 a. (459 aa)
	ENSLBEP00000035019	Uncharacterized protein. (344 aa)
	LOC109988705	Ephrin-A1a; Belongs to the ephrin family. (227 aa)
	ryk	Receptor like tyrosine kinase. (630 aa)
	LOC110002051	Disco interacting protein 2 homolog C. (1430 aa)
	LOC109981821	Uncharacterized protein; Belongs to the semaphorin family. (886 aa)
	LOC110001516	Sema domain-containing protein; Belongs to the semaphorin family. (783 aa)
	ENSLBEP00000038697	Uncharacterized protein. (65 aa)
	LOC109979845	Sialidase domain-containing protein. (287 aa)
	LOC109994544	UPF0258 domain-containing protein. (804 aa)
	cib1	Calcium and integrin binding 1 (calmyrin). (189 aa)

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSLBEP00000001605	ENSLBEP00000035019	ENSLBEP00000001605	ENSLBEP00000035019	Uncharacterized protein.	Uncharacterized protein.	0.712
ENSLBEP00000001605	LOC109988379	ENSLBEP00000001605	ENSLBEP00000017291	Uncharacterized protein.	FAT atypical cadherin 3b.	0.674
ENSLBEP00000010675	LOC109982581	ENSLBEP00000010675	ENSLBEP00000033424	Uncharacterized protein.	Ubiquitin protein ligase E3A.	0.839
ENSLBEP00000010675	LOC109984039	ENSLBEP00000010675	ENSLBEP00000002687	Uncharacterized protein.	Uncharacterized protein.	0.410
ENSLBEP00000010675	LOC110004756	ENSLBEP00000010675	ENSLBEP00000027698	Uncharacterized protein.	Si:ch73-40a2.1.	0.410
ENSLBEP00000010675	UBE3A	ENSLBEP00000010675	ENSLBEP00000025631	Uncharacterized protein.	Ubiquitin protein ligase E3A.	0.859
ENSLBEP00000010675	epha4	ENSLBEP00000010675	ENSLBEP00000023917	Uncharacterized protein.	Eph receptor A4, like.	0.410
ENSLBEP00000035019	ENSLBEP00000001605	ENSLBEP00000035019	ENSLBEP00000001605	Uncharacterized protein.	Uncharacterized protein.	0.712
ENSLBEP00000035019	LOC109988379	ENSLBEP00000035019	ENSLBEP00000017291	Uncharacterized protein.	FAT atypical cadherin 3b.	0.671
LOC109975235	cdk5	ENSLBEP00000023732	ENSLBEP00000001893	Sema domain-containing protein; Belongs to the semaphorin family.	Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily.	0.442
LOC109980617	cdk5	ENSLBEP00000028145	ENSLBEP00000001893	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fa; Belongs to the semaphorin family.	Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily.	0.442
LOC109981821	LOC109984042	ENSLBEP00000037710	ENSLBEP00000001761	Uncharacterized protein; Belongs to the semaphorin family.	Semaphorin 4e; Belongs to the semaphorin family.	0.569
LOC109981821	LOC109993644	ENSLBEP00000037710	ENSLBEP00000014911	Uncharacterized protein; Belongs to the semaphorin family.	Sema domain-containing protein; Belongs to the semaphorin family.	0.526
LOC109981821	LOC109998617	ENSLBEP00000037710	ENSLBEP00000007541	Uncharacterized protein; Belongs to the semaphorin family.	Si:ch211-129c21.1; Belongs to the semaphorin family.	0.569
LOC109981821	LOC109999299	ENSLBEP00000037710	ENSLBEP00000008615	Uncharacterized protein; Belongs to the semaphorin family.	Sema domain-containing protein; Belongs to the semaphorin family.	0.526
LOC109981821	LOC110001516	ENSLBEP00000037710	ENSLBEP00000038069	Uncharacterized protein; Belongs to the semaphorin family.	Sema domain-containing protein; Belongs to the semaphorin family.	0.526
LOC109981821	SEMA4D	ENSLBEP00000037710	ENSLBEP00000024073	Uncharacterized protein; Belongs to the semaphorin family.	Semaphorin 4D; Belongs to the semaphorin family.	0.569
LOC109981821	cdk5	ENSLBEP00000037710	ENSLBEP00000001893	Uncharacterized protein; Belongs to the semaphorin family.	Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily.	0.557
LOC109981821	sema4b	ENSLBEP00000037710	ENSLBEP00000009354	Uncharacterized protein; Belongs to the semaphorin family.	Sema domain-containing protein; Belongs to the semaphorin family.	0.526
LOC109981886	LOC109992406	ENSLBEP00000004515	ENSLBEP00000015653	Dickkopf WNT signaling pathway inhibitor 1a.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.904