(26 nodes) Protein-hormone receptor activity network (Labrus bergylta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	adipor2	Adiponectin receptor 2. (376 aa)
	ENSLBEP00000017302	G_PROTEIN_RECEP_F1_2 domain-containing protein. (414 aa)
	ENSLBEP00000016740	Recep_L_domain domain-containing protein. (281 aa)
	igf1r	Tyrosine-protein kinase receptor. (1417 aa)
	LOC109986664	Formyl peptide receptor 1; Belongs to the G-protein coupled receptor 1 family. (361 aa)
	LOC109986661	Formyl peptide receptor 1; Belongs to the G-protein coupled receptor 1 family. (380 aa)
	LOC109983204	G_PROTEIN_RECEP_F1_2 domain-containing protein. (648 aa)
	LGR6	Leucine rich repeat containing G protein-coupled receptor 6. (976 aa)
	LOC110003706	G_PROTEIN_RECEP_F1_2 domain-containing protein. (630 aa)
	GNRHR	Gonadotropin releasing hormone receptor. (403 aa)
	LOC109999298	G_PROTEIN_RECEP_F1_2 domain-containing protein. (394 aa)
	insr	Tyrosine-protein kinase receptor. (1364 aa)
	LOC110004382	G_PROTEIN_RECEP_F1_2 domain-containing protein. (627 aa)
	tshr	Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (759 aa)
	LOC109987794	Tyrosine-protein kinase receptor. (1276 aa)
	gpr1	G protein-coupled receptor 1; Belongs to the G-protein coupled receptor 1 family. (359 aa)
	ENSLBEP00000003746	G_PROTEIN_RECEP_F1_2 domain-containing protein. (153 aa)
	lgr4	Leucine-rich repeat containing G protein-coupled receptor 4. (945 aa)
	LOC109987527	Gonadotropin releasing hormone receptor 1; Belongs to the G-protein coupled receptor 1 family. (382 aa)
	LOC109993303	Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (644 aa)
	adipor1	Adiponectin receptor 1a. (376 aa)
	cmklr1	Chemokine-like receptor 1; Belongs to the G-protein coupled receptor 1 family. (351 aa)
	LOC109999191	Melanin-concentrating hormone receptor 1a. (362 aa)
	LOC110003020	Melanin-concentrating hormone receptor 1b. (364 aa)
	dcaf8	DDB1 and CUL4 associated factor 8. (625 aa)
	AMHR2	TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (557 aa)

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSLBEP00000003746	LOC110004382	ENSLBEP00000003746	ENSLBEP00000007713	G_PROTEIN_RECEP_F1_2 domain-containing protein.	G_PROTEIN_RECEP_F1_2 domain-containing protein.	0.656
ENSLBEP00000003746	lgr4	ENSLBEP00000003746	ENSLBEP00000003102	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Leucine-rich repeat containing G protein-coupled receptor 4.	0.656
ENSLBEP00000017302	GNRHR	ENSLBEP00000017302	ENSLBEP00000009460	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Gonadotropin releasing hormone receptor.	0.828
ENSLBEP00000017302	LOC109987527	ENSLBEP00000017302	ENSLBEP00000037583	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Gonadotropin releasing hormone receptor 1; Belongs to the G-protein coupled receptor 1 family.	0.833
ENSLBEP00000017302	LOC109999298	ENSLBEP00000017302	ENSLBEP00000008908	G_PROTEIN_RECEP_F1_2 domain-containing protein.	G_PROTEIN_RECEP_F1_2 domain-containing protein.	0.723
GNRHR	ENSLBEP00000017302	ENSLBEP00000009460	ENSLBEP00000017302	Gonadotropin releasing hormone receptor.	G_PROTEIN_RECEP_F1_2 domain-containing protein.	0.828
GNRHR	LOC109987527	ENSLBEP00000009460	ENSLBEP00000037583	Gonadotropin releasing hormone receptor.	Gonadotropin releasing hormone receptor 1; Belongs to the G-protein coupled receptor 1 family.	0.846
LGR6	LOC110004382	ENSLBEP00000011432	ENSLBEP00000007713	Leucine rich repeat containing G protein-coupled receptor 6.	G_PROTEIN_RECEP_F1_2 domain-containing protein.	0.864
LGR6	lgr4	ENSLBEP00000011432	ENSLBEP00000003102	Leucine rich repeat containing G protein-coupled receptor 6.	Leucine-rich repeat containing G protein-coupled receptor 4.	0.865
LOC109983204	LOC110004382	ENSLBEP00000014251	ENSLBEP00000007713	G_PROTEIN_RECEP_F1_2 domain-containing protein.	G_PROTEIN_RECEP_F1_2 domain-containing protein.	0.656
LOC109983204	lgr4	ENSLBEP00000014251	ENSLBEP00000003102	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Leucine-rich repeat containing G protein-coupled receptor 4.	0.656
LOC109987527	ENSLBEP00000017302	ENSLBEP00000037583	ENSLBEP00000017302	Gonadotropin releasing hormone receptor 1; Belongs to the G-protein coupled receptor 1 family.	G_PROTEIN_RECEP_F1_2 domain-containing protein.	0.833
LOC109987527	GNRHR	ENSLBEP00000037583	ENSLBEP00000009460	Gonadotropin releasing hormone receptor 1; Belongs to the G-protein coupled receptor 1 family.	Gonadotropin releasing hormone receptor.	0.846
LOC109987527	LOC109999298	ENSLBEP00000037583	ENSLBEP00000008908	Gonadotropin releasing hormone receptor 1; Belongs to the G-protein coupled receptor 1 family.	G_PROTEIN_RECEP_F1_2 domain-containing protein.	0.837
LOC109987794	igf1r	ENSLBEP00000007125	ENSLBEP00000014965	Tyrosine-protein kinase receptor.	Tyrosine-protein kinase receptor.	0.835
LOC109993303	LOC110004382	ENSLBEP00000036162	ENSLBEP00000007713	Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.	G_PROTEIN_RECEP_F1_2 domain-containing protein.	0.656
LOC109993303	lgr4	ENSLBEP00000036162	ENSLBEP00000003102	Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.	Leucine-rich repeat containing G protein-coupled receptor 4.	0.656
LOC109999191	LOC110003020	ENSLBEP00000000185	ENSLBEP00000022601	Melanin-concentrating hormone receptor 1a.	Melanin-concentrating hormone receptor 1b.	0.841
LOC109999298	ENSLBEP00000017302	ENSLBEP00000008908	ENSLBEP00000017302	G_PROTEIN_RECEP_F1_2 domain-containing protein.	G_PROTEIN_RECEP_F1_2 domain-containing protein.	0.723
LOC109999298	LOC109987527	ENSLBEP00000008908	ENSLBEP00000037583	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Gonadotropin releasing hormone receptor 1; Belongs to the G-protein coupled receptor 1 family.	0.837