(40 nodes) Peptidase activator activity network (Labrus bergylta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC109992188	Uncharacterized protein. (1795 aa)
	vsir	V-set immunoregulatory receptor. (289 aa)
	LOC109985396	RPN13_C domain-containing protein. (415 aa)
	ENSLBEP00000037371	FZ domain-containing protein. (284 aa)
	psme1	Proteasome activator subunit 1. (252 aa)
	casp8ap2	Uncharacterized protein. (1908 aa)
	LOC109986942	DUF4203 domain-containing protein. (333 aa)
	bad	BCL2 associated agonist of cell death b. (221 aa)
	LOC109992495	Transmembrane protein 198-like. (342 aa)
	clpx	Caseinolytic mitochondrial matrix peptidase chaperone subunit b. (624 aa)
	psme2	Proteasome activator subunit 2. (340 aa)
	ENSLBEP00000024592	Inhibitor_I29 domain-containing protein. (125 aa)
	LOC109982254	Cathepsin H; Belongs to the peptidase C1 family. (305 aa)
	LOC109987373	Fibronectin 1a. (2192 aa)
	LOC109980712	Procollagen C-endopeptidase enhancer b. (511 aa)
	FBLN1	Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes. (689 aa)
	LOC110005506	Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes. (697 aa)
	LOC109991021	Procollagen C-endopeptidase enhancer a. (472 aa)
	LOC109977454	DUF4203 domain-containing protein. (342 aa)
	wdr48	WD repeat domain 48b. (669 aa)
	ENSLBEP00000004713	Transmembrane protein 198a. (363 aa)
	sfrp2	Secreted frizzled-related protein 2. (295 aa)
	ebag9	Estrogen receptor binding site associated antigen 9; May participate in suppression of cell proliferation and induces apoptotic cell death through activation of interleukin-1-beta converting enzyme (ICE)-like proteases. (223 aa)
	psmd14	Proteasome 26S subunit, non-ATPase 14. (310 aa)
	pcolce2	Procollagen C-endopeptidase enhancer 2b. (405 aa)
	ctsc	Cathepsin C; Belongs to the peptidase C1 family. (458 aa)
	LOC110001654	NK3 homeobox 1. (191 aa)
	ENSLBEP00000007449	TBD domain-containing protein. (236 aa)
	CTSH	Cathepsin H; Belongs to the peptidase C1 family. (238 aa)
	PSME2	Proteasome activator subunit 2. (245 aa)
	LOC110000530	Adhesion regulating molecule 1. (388 aa)
	bcl2l13	BCL2 like 13. (487 aa)
	psenen	Uncharacterized protein. (66 aa)
	LOC109980933	Endo/exonuclease/phosphatase domain-containing protein. (348 aa)
	LOC109993596	Uncharacterized protein. (233 aa)
	psme3	Proteasome activator subunit 3. (267 aa)
	psme4	Proteasome activator subunit 4a. (1755 aa)
	LOC109994773	Transmembrane protein 198b. (420 aa)
	LOC109997614	Deoxyribonuclease; Belongs to the DNase I family. (298 aa)
	LOC109990113	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (154 aa)

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CTSH	ctsc	ENSLBEP00000008998	ENSLBEP00000006137	Cathepsin H; Belongs to the peptidase C1 family.	Cathepsin C; Belongs to the peptidase C1 family.	0.768
ENSLBEP00000024592	ctsc	ENSLBEP00000024592	ENSLBEP00000006137	Inhibitor_I29 domain-containing protein.	Cathepsin C; Belongs to the peptidase C1 family.	0.768
ENSLBEP00000037371	LOC109990113	ENSLBEP00000037371	ENSLBEP00000015571	FZ domain-containing protein.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.407
FBLN1	psenen	ENSLBEP00000038109	ENSLBEP00000013125	Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes.	Uncharacterized protein.	0.577
LOC109982254	ctsc	ENSLBEP00000024653	ENSLBEP00000006137	Cathepsin H; Belongs to the peptidase C1 family.	Cathepsin C; Belongs to the peptidase C1 family.	0.768
LOC109985396	LOC109992188	ENSLBEP00000019242	ENSLBEP00000032566	RPN13_C domain-containing protein.	Uncharacterized protein.	0.837
LOC109985396	LOC110000530	ENSLBEP00000019242	ENSLBEP00000012091	RPN13_C domain-containing protein.	Adhesion regulating molecule 1.	0.837
LOC109985396	PSME2	ENSLBEP00000019242	ENSLBEP00000012003	RPN13_C domain-containing protein.	Proteasome activator subunit 2.	0.757
LOC109985396	psmd14	ENSLBEP00000019242	ENSLBEP00000034512	RPN13_C domain-containing protein.	Proteasome 26S subunit, non-ATPase 14.	0.990
LOC109985396	psme1	ENSLBEP00000019242	ENSLBEP00000036540	RPN13_C domain-containing protein.	Proteasome activator subunit 1.	0.760
LOC109985396	psme2	ENSLBEP00000019242	ENSLBEP00000022621	RPN13_C domain-containing protein.	Proteasome activator subunit 2.	0.757
LOC109985396	psme3	ENSLBEP00000019242	ENSLBEP00000014027	RPN13_C domain-containing protein.	Proteasome activator subunit 3.	0.787
LOC109985396	psme4	ENSLBEP00000019242	ENSLBEP00000014674	RPN13_C domain-containing protein.	Proteasome activator subunit 4a.	0.837
LOC109990113	ENSLBEP00000037371	ENSLBEP00000015571	ENSLBEP00000037371	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	FZ domain-containing protein.	0.407
LOC109990113	sfrp2	ENSLBEP00000015571	ENSLBEP00000004882	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Secreted frizzled-related protein 2.	0.407
LOC109992188	LOC109985396	ENSLBEP00000032566	ENSLBEP00000019242	Uncharacterized protein.	RPN13_C domain-containing protein.	0.837
LOC109992188	LOC110000530	ENSLBEP00000032566	ENSLBEP00000012091	Uncharacterized protein.	Adhesion regulating molecule 1.	0.837
LOC109992188	psmd14	ENSLBEP00000032566	ENSLBEP00000034512	Uncharacterized protein.	Proteasome 26S subunit, non-ATPase 14.	0.944
LOC109992188	psme1	ENSLBEP00000032566	ENSLBEP00000036540	Uncharacterized protein.	Proteasome activator subunit 1.	0.472
LOC109992188	psme3	ENSLBEP00000032566	ENSLBEP00000014027	Uncharacterized protein.	Proteasome activator subunit 3.	0.544