(94 nodes) Metencephalon development network (Labrus bergylta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC109979395	Uncharacterized protein. (289 aa)
	LOC110001732	PX domain-containing protein. (351 aa)
	mecp2	Methyl CpG binding protein 2. (1036 aa)
	ENSLBEP00000015994	Cyclin-dependent kinase 5 activator. (308 aa)
	ENSLBEP00000015634	Uncharacterized protein. (182 aa)
	wnt1	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
	LOC109975802	G_PROTEIN_RECEP_F2_4 domain-containing protein; Belongs to the G-protein coupled receptor Fz/Smo family. (373 aa)
	ENSLBEP00000007781	Peptidase_M14 domain-containing protein. (205 aa)
	cep55	Centrosomal protein 55 like. (499 aa)
	MAFB	MAF bZIP transcription factor B. (244 aa)
	LOC109981479	Seizure related 6 homolog a. (990 aa)
	LOC109981481	LIM homeobox 1b. (412 aa)
	srrm4	Serine/arginine repetitive matrix 4. (625 aa)
	LOC109990055	Si:ch73-21k16.5; Belongs to the GPAT/DAPAT family. (667 aa)
	ENSLBEP00000011188	Uncharacterized protein. (164 aa)
	LOC109992992	Paired box 2b. (391 aa)
	LOC109997535	Cyclin-dependent kinase 5 activator. (336 aa)
	ENSLBEP00000011805	Paired domain-containing protein. (246 aa)
	ENSLBEP00000012249	Uncharacterized protein. (490 aa)
	LOC109996946	N-acetylglucosaminidase, alpha. (749 aa)
	crkl	V-crk avian sarcoma virus CT10 oncogene homolog-like. (318 aa)
	clp1	Polyribonucleotide 5'-hydroxyl-kinase Clp1; Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; thi [...] (445 aa)
	ENSLBEP00000007512	Uncharacterized protein. (124 aa)
	chmp1a	Charged multivesicular body protein 1A. (198 aa)
	kndc1	Uncharacterized protein. (1811 aa)
	abl2	Tyrosine-protein kinase. (1213 aa)
	rpgrip1l	RPGRIP1 like. (1260 aa)
	gbx2	Gastrulation brain homeobox 2. (313 aa)
	ttc21b	Tetratricopeptide repeat domain 21B. (1311 aa)
	fzd4	Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (530 aa)
	LOC110005608	Uncharacterized protein; Belongs to the heat shock protein 70 family. (671 aa)
	NCSTN	Nicastrin. (701 aa)
	ENSLBEP00000005736	Uncharacterized protein; Belongs to the heat shock protein 70 family. (642 aa)
	ENSLBEP00000005650	Si:ch211-160f23.7. (245 aa)
	LOC109975544	Heat shock protein 5; Belongs to the heat shock protein 70 family. (654 aa)
	klhl5	Kelch-like family member 5. (793 aa)
	pax5	Paired box 5. (396 aa)
	agtpbp1	ATP/GTP binding protein 1. (1088 aa)
	cep290	Centrosomal protein 290. (2289 aa)
	LOC109989420	Whirlin b. (840 aa)
	LOC109981389	Orthodenticle homeobox 2b. (290 aa)
	cdk5	Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
	LOC109986491	Kelch-like family member 4. (733 aa)
	LOC109981909	Paired box 2a. (417 aa)
	ENSLBEP00000000720	Uncharacterized protein; Belongs to the heat shock protein 70 family. (655 aa)
	ENSLBEP00000000610	Uncharacterized protein; Belongs to the heat shock protein 70 family. (635 aa)
	coq8b	Coenzyme Q8B. (629 aa)
	ENSLBEP00000014437	Uncharacterized protein. (165 aa)
	ENSLBEP00000013812	Uncharacterized protein. (371 aa)
	ENSLBEP00000013723	CUB domain-containing protein. (330 aa)
	ENSLBEP00000038776	Uncharacterized protein. (128 aa)
	ENSLBEP00000038778	Uncharacterized protein. (387 aa)
	LOC109976588	Uncharacterized protein; Belongs to the heat shock protein 70 family. (654 aa)
	ENSLBEP00000027932	Uncharacterized protein. (342 aa)
	pdss2	Prenyl (decaprenyl) diphosphate synthase, subunit 2; Belongs to the FPP/GGPP synthase family. (384 aa)
	ENSLBEP00000027449	Uncharacterized protein. (230 aa)
	fgf3	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (247 aa)
	cdk5r2	Cyclin-dependent kinase 5 activator. (302 aa)
	LOC109976615	Uncharacterized protein. (281 aa)
	LOC110002643	ATP/GTP binding protein-like 1. (960 aa)
	LOC109985173	Homeobox protein engrailed-like. (292 aa)
	kif14	Kinesin family member 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1184 aa)
	crk	CRK proto-oncogene, adaptor protein. (315 aa)
	xrcc1	X-ray repair complementing defective repair in Chinese hamster cells 1. (625 aa)
	LOC109998954	Uncharacterized protein. (322 aa)
	rbm7	RNA binding motif protein 7. (262 aa)
	LOC109982938	Homeobox domain-containing protein. (291 aa)
	gnpat	Glyceronephosphate O-acyltransferase; Belongs to the GPAT/DAPAT family. (687 aa)
	LOC109989290	Seizure related 6 homolog b. (945 aa)
	lhx1	LIM homeobox 1a. (407 aa)
	bmp2	Bone morphogenetic protein 2b. (422 aa)
	sez6l2	Seizure related 6 homolog (mouse)-like 2. (549 aa)
	LOC109997314	Homeobox protein engrailed-like. (285 aa)
	ttll1	Tubulin tyrosine ligase-like family, member 1. (424 aa)
	LOC109994528	Ubiquinol-cytochrome c reductase, complex III subunit VII. (82 aa)
	LOC110002808	Uncharacterized protein; Belongs to the heat shock protein 70 family. (653 aa)
	LOC110002809	Uncharacterized protein; Belongs to the heat shock protein 70 family. (654 aa)
	ENSLBEP00000036456	Uncharacterized protein; Belongs to the heat shock protein 70 family. (617 aa)
	phox2a	Paired like homeobox 2A. (342 aa)
	ENSLBEP00000026733	Uncharacterized protein. (115 aa)
	rest	RE1-silencing transcription factor. (1018 aa)
	abl1	Tyrosine-protein kinase. (1132 aa)
	whrn	Whirlin a. (984 aa)
	LOC109999551	WD repeat domain 73. (377 aa)
	ENSLBEP00000023548	Uncharacterized protein. (250 aa)
	serpine2	Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2; Belongs to the serpin family. (397 aa)
	LOC109990249	Cyclin-dependent kinase 5 activator. (327 aa)
	LOC109996609	Paired box 8. (475 aa)
	smo	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (825 aa)
	ENSLBEP00000021437	Uncharacterized protein. (247 aa)
	LOC110005888	Uncharacterized protein. (754 aa)
	ENSLBEP00000038339	Bmi1 polycomb ring finger oncogene 1a. (336 aa)
	LOC109987197	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa)
	SNX14	Sorting nexin 14. (989 aa)

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSLBEP00000011188	rpgrip1l	ENSLBEP00000011188	ENSLBEP00000006721	Uncharacterized protein.	RPGRIP1 like.	0.587
ENSLBEP00000011188	ttc21b	ENSLBEP00000011188	ENSLBEP00000006564	Uncharacterized protein.	Tetratricopeptide repeat domain 21B.	0.478
ENSLBEP00000011805	LOC109981481	ENSLBEP00000011805	ENSLBEP00000009753	Paired domain-containing protein.	LIM homeobox 1b.	0.416
ENSLBEP00000011805	lhx1	ENSLBEP00000011805	ENSLBEP00000033737	Paired domain-containing protein.	LIM homeobox 1a.	0.421
ENSLBEP00000013812	ENSLBEP00000038339	ENSLBEP00000013812	ENSLBEP00000038339	Uncharacterized protein.	Bmi1 polycomb ring finger oncogene 1a.	0.418
ENSLBEP00000013812	mecp2	ENSLBEP00000013812	ENSLBEP00000016265	Uncharacterized protein.	Methyl CpG binding protein 2.	0.810
ENSLBEP00000015634	LOC110001732	ENSLBEP00000015634	ENSLBEP00000017842	Uncharacterized protein.	PX domain-containing protein.	0.778
ENSLBEP00000015994	cdk5	ENSLBEP00000015994	ENSLBEP00000001893	Cyclin-dependent kinase 5 activator.	Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily.	0.976
ENSLBEP00000023548	smo	ENSLBEP00000023548	ENSLBEP00000022377	Uncharacterized protein.	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.603
ENSLBEP00000027449	LOC110001732	ENSLBEP00000027449	ENSLBEP00000017842	Uncharacterized protein.	PX domain-containing protein.	0.921
ENSLBEP00000038339	ENSLBEP00000013812	ENSLBEP00000038339	ENSLBEP00000013812	Bmi1 polycomb ring finger oncogene 1a.	Uncharacterized protein.	0.418
ENSLBEP00000038339	LOC109999551	ENSLBEP00000038339	ENSLBEP00000024078	Bmi1 polycomb ring finger oncogene 1a.	WD repeat domain 73.	0.418
LOC109975802	wnt1	ENSLBEP00000015559	ENSLBEP00000015591	G_PROTEIN_RECEP_F2_4 domain-containing protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.923
LOC109976615	mecp2	ENSLBEP00000029154	ENSLBEP00000016265	Uncharacterized protein.	Methyl CpG binding protein 2.	0.496
LOC109979395	cdk5	ENSLBEP00000018646	ENSLBEP00000001893	Uncharacterized protein.	Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily.	0.976
LOC109981481	ENSLBEP00000011805	ENSLBEP00000009753	ENSLBEP00000011805	LIM homeobox 1b.	Paired domain-containing protein.	0.416
LOC109981481	LOC109981909	ENSLBEP00000009753	ENSLBEP00000000870	LIM homeobox 1b.	Paired box 2a.	0.416
LOC109981481	LOC109992992	ENSLBEP00000009753	ENSLBEP00000011309	LIM homeobox 1b.	Paired box 2b.	0.416
LOC109981481	LOC109996609	ENSLBEP00000009753	ENSLBEP00000022678	LIM homeobox 1b.	Paired box 8.	0.416
LOC109981481	pax5	ENSLBEP00000009753	ENSLBEP00000004587	LIM homeobox 1b.	Paired box 5.	0.416