(41 nodes) Signaling receptor complex adaptor activity network (Labrus bergylta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC109980570	Guanine nucleotide binding protein (G protein), beta polypeptide 1b. (340 aa)
	ENSLBEP00000000453	SH3 and multiple ankyrin repeat domains 3a. (1322 aa)
	LOC110002047	PDZ domain-containing protein. (164 aa)
	dok3	IRS-type PTB domain-containing protein. (502 aa)
	gab2	GRB2-associated binding protein 2. (645 aa)
	shank2	SH3 and multiple ankyrin repeat domains 2a. (1805 aa)
	lrrk2	Leucine-rich repeat kinase 2. (2422 aa)
	LOC109988181	IRS-type PTB domain-containing protein. (507 aa)
	poc1b	POC1 centriolar protein B. (525 aa)
	shank1	SH3 and multiple ankyrin repeat domains 1. (840 aa)
	ENSLBEP00000004978	PDZ domain-containing protein. (119 aa)
	LOC110001009	Sperm associated antigen 9a. (1294 aa)
	sh2b1	SH2B adaptor protein 1. (900 aa)
	LOC110006097	Fibroblast growth factor receptor substrate 2b. (509 aa)
	LOC109995880	Docking protein 2. (583 aa)
	GNB5	G protein subunit beta 5. (395 aa)
	LOC109981017	Glutamate receptor interacting protein 2a. (995 aa)
	gnb1	Guanine nucleotide binding protein (G protein), beta polypeptide 1a. (360 aa)
	gnb3	Guanine nucleotide binding protein (G protein), beta polypeptide 3a. (340 aa)
	FRS2	Fibroblast growth factor receptor substrate 2. (488 aa)
	ldlrap1	Low density lipoprotein receptor adaptor protein 1b. (313 aa)
	LOC109993679	Si:dkey-17m8.1. (992 aa)
	POC1A	POC1 centriolar protein A. (468 aa)
	gnb5	Guanine nucleotide binding protein (G protein), beta 5a. (353 aa)
	LOC109997068	Guanine nucleotide binding protein (G protein), beta polypeptide 2. (340 aa)
	LOC109991367	Docking protein 1b. (698 aa)
	sav1	Salvador family WW domain containing protein 1. (400 aa)
	sh2b3	SH2B adaptor protein 3. (735 aa)
	ENSLBEP00000023069	Uncharacterized protein. (86 aa)
	LOC109976009	Guanine nucleotide binding protein (G protein), beta polypeptide 3b. (342 aa)
	LOC109998849	Membrane associated guanylate kinase, WW and PDZ domain containing 2a. (1316 aa)
	LOC109990363	Fibroblast growth factor receptor substrate 3. (619 aa)
	LOC110002615	Uncharacterized protein. (1201 aa)
	ENSLBEP00000027466	PDZ domain-containing protein. (150 aa)
	grip2	Glutamate receptor interacting protein 2b. (995 aa)
	SH2B2	SH2B adaptor protein 2. (703 aa)
	SPAG9	Sperm associated antigen 9. (1330 aa)
	mapk8ip3	Mitogen-activated protein kinase 8 interacting protein 3. (1359 aa)
	tradd	Tnfrsf1a-associated via death domain. (291 aa)
	ENSLBEP00000033183	Uncharacterized protein. (230 aa)
	LOC109995047	Guanine nucleotide binding protein (G protein), beta polypeptide 4b. (345 aa)

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSLBEP00000000453	ENSLBEP00000023069	ENSLBEP00000000453	ENSLBEP00000023069	SH3 and multiple ankyrin repeat domains 3a.	Uncharacterized protein.	0.878
ENSLBEP00000000453	ENSLBEP00000033183	ENSLBEP00000000453	ENSLBEP00000033183	SH3 and multiple ankyrin repeat domains 3a.	Uncharacterized protein.	0.738
ENSLBEP00000000453	shank1	ENSLBEP00000000453	ENSLBEP00000004795	SH3 and multiple ankyrin repeat domains 3a.	SH3 and multiple ankyrin repeat domains 1.	0.720
ENSLBEP00000000453	shank2	ENSLBEP00000000453	ENSLBEP00000002047	SH3 and multiple ankyrin repeat domains 3a.	SH3 and multiple ankyrin repeat domains 2a.	0.720
ENSLBEP00000004978	gab2	ENSLBEP00000004978	ENSLBEP00000001020	PDZ domain-containing protein.	GRB2-associated binding protein 2.	0.477
ENSLBEP00000023069	ENSLBEP00000000453	ENSLBEP00000023069	ENSLBEP00000000453	Uncharacterized protein.	SH3 and multiple ankyrin repeat domains 3a.	0.878
ENSLBEP00000023069	ENSLBEP00000033183	ENSLBEP00000023069	ENSLBEP00000033183	Uncharacterized protein.	Uncharacterized protein.	0.878
ENSLBEP00000023069	shank1	ENSLBEP00000023069	ENSLBEP00000004795	Uncharacterized protein.	SH3 and multiple ankyrin repeat domains 1.	0.878
ENSLBEP00000023069	shank2	ENSLBEP00000023069	ENSLBEP00000002047	Uncharacterized protein.	SH3 and multiple ankyrin repeat domains 2a.	0.878
ENSLBEP00000027466	LOC110002615	ENSLBEP00000027466	ENSLBEP00000027222	PDZ domain-containing protein.	Uncharacterized protein.	0.579
ENSLBEP00000027466	sav1	ENSLBEP00000027466	ENSLBEP00000022658	PDZ domain-containing protein.	Salvador family WW domain containing protein 1.	0.680
ENSLBEP00000033183	ENSLBEP00000000453	ENSLBEP00000033183	ENSLBEP00000000453	Uncharacterized protein.	SH3 and multiple ankyrin repeat domains 3a.	0.738
ENSLBEP00000033183	ENSLBEP00000023069	ENSLBEP00000033183	ENSLBEP00000023069	Uncharacterized protein.	Uncharacterized protein.	0.878
ENSLBEP00000033183	shank1	ENSLBEP00000033183	ENSLBEP00000004795	Uncharacterized protein.	SH3 and multiple ankyrin repeat domains 1.	0.720
ENSLBEP00000033183	shank2	ENSLBEP00000033183	ENSLBEP00000002047	Uncharacterized protein.	SH3 and multiple ankyrin repeat domains 2a.	0.720
FRS2	gab2	ENSLBEP00000017083	ENSLBEP00000001020	Fibroblast growth factor receptor substrate 2.	GRB2-associated binding protein 2.	0.603
GNB5	LOC109980570	ENSLBEP00000012000	ENSLBEP00000030291	G protein subunit beta 5.	Guanine nucleotide binding protein (G protein), beta polypeptide 1b.	0.744
GNB5	LOC109995047	ENSLBEP00000012000	ENSLBEP00000036388	G protein subunit beta 5.	Guanine nucleotide binding protein (G protein), beta polypeptide 4b.	0.739
GNB5	LOC109997068	ENSLBEP00000012000	ENSLBEP00000021912	G protein subunit beta 5.	Guanine nucleotide binding protein (G protein), beta polypeptide 2.	0.739
LOC109980570	GNB5	ENSLBEP00000030291	ENSLBEP00000012000	Guanine nucleotide binding protein (G protein), beta polypeptide 1b.	G protein subunit beta 5.	0.744