(21 nodes) Macrophage differentiation network (Labrus bergylta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSLBEP00000035378	CCAAT enhancer binding protein alpha. (130 aa)
	ENSLBEP00000036378	BZIP domain-containing protein. (282 aa)
	nrros	Negative regulator of reactive oxygen species. (683 aa)
	LOC109981714	Tetraspanin. (220 aa)
	APP	Amyloid beta precursor protein. (646 aa)
	nkx2-3	NK2 homeobox 3. (343 aa)
	ENSLBEP00000028636	Suppressor of cytokine signaling 1a. (209 aa)
	LOC109984320	Caspase 10, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (540 aa)
	LOC109975928	Uncharacterized protein; Belongs to the peptidase C14A family. (242 aa)
	NKX2-3	NK2 homeobox 3. (308 aa)
	sirt1	Sirtuin 1. (681 aa)
	eif2ak1	Eukaryotic translation initiation factor 2-alpha kinase 1. (663 aa)
	ENSLBEP00000012477	Uncharacterized protein. (203 aa)
	LOC109980994	Colony stimulating factor 1b (macrophage). (271 aa)
	LOC109984917	Tetraspanin. (211 aa)
	ENSLBEP00000010546	Uncharacterized protein. (190 aa)
	GAB3	GRB2 associated binding protein 3. (549 aa)
	xpr1	Xenotropic and polytropic retrovirus receptor 1a. (695 aa)
	LOC109995799	Uncharacterized protein; Belongs to the peptidase C14A family. (489 aa)
	vegfa	Vascular endothelial growth factor Ab; Belongs to the PDGF/VEGF growth factor family. (214 aa)
	LOC110002260	Uncharacterized protein. (692 aa)

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC109975928	LOC109984320	ENSLBEP00000019952	ENSLBEP00000022442	Uncharacterized protein; Belongs to the peptidase C14A family.	Caspase 10, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.	0.836
LOC109984320	LOC109975928	ENSLBEP00000022442	ENSLBEP00000019952	Caspase 10, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.836
LOC109984320	LOC109995799	ENSLBEP00000022442	ENSLBEP00000005892	Caspase 10, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.837
LOC109995799	LOC109984320	ENSLBEP00000005892	ENSLBEP00000022442	Uncharacterized protein; Belongs to the peptidase C14A family.	Caspase 10, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.	0.837