(49 nodes) Cholesterol transport network (Labrus bergylta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	vps4a	Vacuolar protein sorting 4 homolog A; Belongs to the AAA ATPase family. (436 aa)
	LOC109983014	Synaptotagmin VIIb. (568 aa)
	podn	Podocan. (584 aa)
	npc2	Niemann-Pick disease, type C2. (149 aa)
	LOC109996289	Apolipoprotein Eb. (276 aa)
	stard5	StAR-related lipid transfer (START) domain containing 5. (211 aa)
	LOC109975219	Uncharacterized protein. (251 aa)
	npc1	Niemann-Pick disease, type C1. (1316 aa)
	ENSLBEP00000022618	LIM zinc-binding domain-containing protein. (94 aa)
	LOC109992482	LIM zinc-binding domain-containing protein. (679 aa)
	LOC109990231	Uncharacterized protein. (251 aa)
	ENSLBEP00000021349	BPI1 domain-containing protein. (456 aa)
	lima1	LIM domain and actin binding 1a. (690 aa)
	ABCG4	ATP binding cassette subfamily G member 4. (639 aa)
	ENSLBEP00000004440	LIM zinc-binding domain-containing protein. (1233 aa)
	LOC110004917	Synaptotagmin VIIb. (345 aa)
	LOC109982539	Uncharacterized protein; Belongs to the AAA ATPase family. (437 aa)
	LOC109980354	Uncharacterized protein; Belongs to the CD36 family. (430 aa)
	scp2	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (535 aa)
	ENSLBEP00000014557	LIM zinc-binding domain-containing protein. (137 aa)
	LOC109991911	Uncharacterized protein. (261 aa)
	ldlrap1	Low density lipoprotein receptor adaptor protein 1b. (313 aa)
	LOC110002498	ATP-binding cassette, sub-family G (WHITE), member 1. (654 aa)
	LOC109977272	Cholesteryl ester transfer protein; Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL; Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family. (467 aa)
	stard3	StAR-related lipid transfer (START) domain containing 3. (450 aa)
	spg11	SPG11 vesicle trafficking associated, spatacsin. (2367 aa)
	relch	RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing. (1190 aa)
	LOC109989500	Apolipoprotein Ba. (4238 aa)
	LOC109995881	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (548 aa)
	ENSLBEP00000012769	LIM zinc-binding domain-containing protein. (93 aa)
	lcat	Lecithin-cholesterol acyltransferase. (434 aa)
	scarb1	Scavenger receptor class B, member 1; Belongs to the CD36 family. (429 aa)
	arv1	ARV1 homolog, fatty acid homeostasis modulator. (239 aa)
	abcg4	ATP-binding cassette, sub-family G (WHITE), member 4a. (642 aa)
	LOC110000801	Cholesteryl ester transfer protein; Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL; Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family. (474 aa)
	abcg8	ATP-binding cassette, sub-family G (WHITE), member 8. (648 aa)
	abcg5	ATP-binding cassette, sub-family G (WHITE), member 5. (660 aa)
	NPC1L1	NPC1 like intracellular cholesterol transporter 1. (1360 aa)
	star	Steroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone. (286 aa)
	stard3nl	STARD3 N-terminal like. (229 aa)
	LOC110002626	ATP-binding cassette, sub-family D (ALD), member 1. (762 aa)
	ENSLBEP00000026791	Vitellogenin domain-containing protein. (736 aa)
	LOC109989658	Vitellogenin domain-containing protein. (2351 aa)
	ENSLBEP00000026611	Uncharacterized protein. (448 aa)
	LOC109989657	Vitellogenin domain-containing protein. (789 aa)
	CEL-2	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (553 aa)
	CEL	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (558 aa)
	ENSLBEP00000024862	Si:dkey-185p13.1. (77 aa)
	VPS4B	Vacuolar protein sorting 4 homolog B; Belongs to the AAA ATPase family. (438 aa)

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCG4	LOC109991911	ENSLBEP00000003831	ENSLBEP00000016221	ATP binding cassette subfamily G member 4.	Uncharacterized protein.	0.690
ABCG4	abcg5	ENSLBEP00000003831	ENSLBEP00000030584	ATP binding cassette subfamily G member 4.	ATP-binding cassette, sub-family G (WHITE), member 5.	0.930
CEL	CEL-2	ENSLBEP00000026318	ENSLBEP00000026564	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	0.832
CEL	LOC109995881	ENSLBEP00000026318	ENSLBEP00000010622	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	0.833
CEL-2	CEL	ENSLBEP00000026564	ENSLBEP00000026318	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	0.832
CEL-2	LOC109995881	ENSLBEP00000026564	ENSLBEP00000010622	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	0.842
ENSLBEP00000021349	ENSLBEP00000026611	ENSLBEP00000021349	ENSLBEP00000026611	BPI1 domain-containing protein.	Uncharacterized protein.	0.614
ENSLBEP00000021349	ENSLBEP00000026791	ENSLBEP00000021349	ENSLBEP00000026791	BPI1 domain-containing protein.	Vitellogenin domain-containing protein.	0.614
ENSLBEP00000021349	LOC109989500	ENSLBEP00000021349	ENSLBEP00000009566	BPI1 domain-containing protein.	Apolipoprotein Ba.	0.614
ENSLBEP00000021349	LOC109989657	ENSLBEP00000021349	ENSLBEP00000026580	BPI1 domain-containing protein.	Vitellogenin domain-containing protein.	0.614
ENSLBEP00000021349	LOC109989658	ENSLBEP00000021349	ENSLBEP00000026726	BPI1 domain-containing protein.	Vitellogenin domain-containing protein.	0.614
ENSLBEP00000021349	LOC109991911	ENSLBEP00000021349	ENSLBEP00000016221	BPI1 domain-containing protein.	Uncharacterized protein.	0.586
ENSLBEP00000021349	LOC109996289	ENSLBEP00000021349	ENSLBEP00000001932	BPI1 domain-containing protein.	Apolipoprotein Eb.	0.434
ENSLBEP00000021349	lcat	ENSLBEP00000021349	ENSLBEP00000011028	BPI1 domain-containing protein.	Lecithin-cholesterol acyltransferase.	0.457
ENSLBEP00000026611	ENSLBEP00000021349	ENSLBEP00000026611	ENSLBEP00000021349	Uncharacterized protein.	BPI1 domain-containing protein.	0.614
ENSLBEP00000026611	ENSLBEP00000026791	ENSLBEP00000026611	ENSLBEP00000026791	Uncharacterized protein.	Vitellogenin domain-containing protein.	0.856
ENSLBEP00000026611	LOC109975219	ENSLBEP00000026611	ENSLBEP00000023316	Uncharacterized protein.	Uncharacterized protein.	0.781
ENSLBEP00000026611	LOC109977272	ENSLBEP00000026611	ENSLBEP00000020928	Uncharacterized protein.	Cholesteryl ester transfer protein; Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL; Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.	0.614
ENSLBEP00000026611	LOC109980354	ENSLBEP00000026611	ENSLBEP00000013933	Uncharacterized protein.	Uncharacterized protein; Belongs to the CD36 family.	0.743
ENSLBEP00000026611	LOC109989657	ENSLBEP00000026611	ENSLBEP00000026580	Uncharacterized protein.	Vitellogenin domain-containing protein.	0.738