(28 nodes) Osteoclast differentiation network (Labrus bergylta)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

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protein homology

Your Input:
	ostm1	Osteoclastogenesis associated transmembrane protein 1. (291 aa)
	LOC109989568	JunB proto-oncogene, AP-1 transcription factor subunit a. (331 aa)
	ENSLBEP00000013258	Uncharacterized protein. (404 aa)
	ENSLBEP00000012477	Uncharacterized protein. (203 aa)
	LOC109980994	Colony stimulating factor 1b (macrophage). (271 aa)
	LOC109977332	Ephrin-A2a; Belongs to the ephrin family. (209 aa)
	ENSLBEP00000010546	Uncharacterized protein. (190 aa)
	ENSLBEP00000008609	Tumor necrosis factor receptor superfamily, member 11a, NFKB activator. (402 aa)
	LOC109985864	FAM20C golgi associated secretory pathway kinase a. (571 aa)
	SRC	Tyrosine-protein kinase. (549 aa)
	DCSTAMP	Dendrocyte expressed seven transmembrane protein. (502 aa)
	LOC110000387	JunB proto-oncogene, AP-1 transcription factor subunit b. (327 aa)
	gab2	GRB2-associated binding protein 2. (645 aa)
	LOC109990439	Fam20C domain-containing protein. (566 aa)
	tcta	T-cell leukemia translocation-altered gene protein homolog. (101 aa)
	LOC109996227	ATPase H+ transporting accessory protein 1b. (449 aa)
	nf1	Neurofibromin 1b. (2672 aa)
	LOC110003903	Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. (220 aa)
	lrrk1	Leucine-rich repeat kinase 1. (1935 aa)
	LOC109986980	TNF superfamily member 11; Belongs to the tumor necrosis factor family. (268 aa)
	LOC109983961	Si:ch211-184m13.4; Belongs to the G-protein coupled receptor 1 family. (342 aa)
	LOC109983967	G protein-coupled receptor 183a; Belongs to the G-protein coupled receptor 1 family. (384 aa)
	LOC110000320	ATPase H+ transporting accessory protein 1a. (486 aa)
	LOC109996231	Tyrosine-protein kinase. (439 aa)
	tmem64	Transmembrane protein 64. (352 aa)
	LOC109995483	Transforming growth factor beta; Belongs to the TGF-beta family. (386 aa)
	GLO1	Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. (180 aa)
	ocstamp	Osteoclast stimulatory transmembrane protein. (468 aa)

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DCSTAMP	LOC109986980	ENSLBEP00000002565	ENSLBEP00000027904	Dendrocyte expressed seven transmembrane protein.	TNF superfamily member 11; Belongs to the tumor necrosis factor family.	0.535
DCSTAMP	ocstamp	ENSLBEP00000002565	ENSLBEP00000020273	Dendrocyte expressed seven transmembrane protein.	Osteoclast stimulatory transmembrane protein.	0.557
ENSLBEP00000008609	LOC109986980	ENSLBEP00000008609	ENSLBEP00000027904	Tumor necrosis factor receptor superfamily, member 11a, NFKB activator.	TNF superfamily member 11; Belongs to the tumor necrosis factor family.	0.995
ENSLBEP00000008609	ostm1	ENSLBEP00000008609	ENSLBEP00000018691	Tumor necrosis factor receptor superfamily, member 11a, NFKB activator.	Osteoclastogenesis associated transmembrane protein 1.	0.424
GLO1	LOC110003903	ENSLBEP00000020873	ENSLBEP00000027028	Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.	Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.	0.840
LOC109977332	LOC109996231	ENSLBEP00000011953	ENSLBEP00000031227	Ephrin-A2a; Belongs to the ephrin family.	Tyrosine-protein kinase.	0.648
LOC109977332	SRC	ENSLBEP00000011953	ENSLBEP00000004031	Ephrin-A2a; Belongs to the ephrin family.	Tyrosine-protein kinase.	0.648
LOC109986980	DCSTAMP	ENSLBEP00000027904	ENSLBEP00000002565	TNF superfamily member 11; Belongs to the tumor necrosis factor family.	Dendrocyte expressed seven transmembrane protein.	0.535
LOC109986980	ENSLBEP00000008609	ENSLBEP00000027904	ENSLBEP00000008609	TNF superfamily member 11; Belongs to the tumor necrosis factor family.	Tumor necrosis factor receptor superfamily, member 11a, NFKB activator.	0.995
LOC109986980	ostm1	ENSLBEP00000027904	ENSLBEP00000018691	TNF superfamily member 11; Belongs to the tumor necrosis factor family.	Osteoclastogenesis associated transmembrane protein 1.	0.420
LOC109996231	LOC109977332	ENSLBEP00000031227	ENSLBEP00000011953	Tyrosine-protein kinase.	Ephrin-A2a; Belongs to the ephrin family.	0.648
LOC109996231	SRC	ENSLBEP00000031227	ENSLBEP00000004031	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.840
LOC109996231	gab2	ENSLBEP00000031227	ENSLBEP00000001020	Tyrosine-protein kinase.	GRB2-associated binding protein 2.	0.637
LOC110003903	GLO1	ENSLBEP00000027028	ENSLBEP00000020873	Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.	Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.	0.840
SRC	LOC109977332	ENSLBEP00000004031	ENSLBEP00000011953	Tyrosine-protein kinase.	Ephrin-A2a; Belongs to the ephrin family.	0.648
SRC	LOC109996231	ENSLBEP00000004031	ENSLBEP00000031227	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.840
SRC	gab2	ENSLBEP00000004031	ENSLBEP00000001020	Tyrosine-protein kinase.	GRB2-associated binding protein 2.	0.637
gab2	LOC109996231	ENSLBEP00000001020	ENSLBEP00000031227	GRB2-associated binding protein 2.	Tyrosine-protein kinase.	0.637
gab2	SRC	ENSLBEP00000001020	ENSLBEP00000004031	GRB2-associated binding protein 2.	Tyrosine-protein kinase.	0.637
ocstamp	DCSTAMP	ENSLBEP00000020273	ENSLBEP00000002565	Osteoclast stimulatory transmembrane protein.	Dendrocyte expressed seven transmembrane protein.	0.557