(20 nodes) Rough endoplasmic reticulum membrane network (Labrus bergylta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	tmem97	Transmembrane protein 97; Intracellular orphan receptor that binds numerous drugs and which is highly expressed in various proliferating cells. Corresponds to the sigma-2 receptor, which is thought to play important role in regulating cell survival, morphology and differentiation. May play a role as a regulator of cellular cholesterol homeostasis. May function as sterol isomerase. May alter the activity of some cytochrome P450 proteins. (170 aa)
	LOC109999113	Zinc finger CCCH-type containing 12A. (627 aa)
	RPS29	Ribosomal protein S29. (74 aa)
	LOC110003253	Phosphatidylinositol 4-kinase, catalytic, beta; Belongs to the PI3/PI4-kinase family. (818 aa)
	LOC109979846	SRP receptor subunit beta. (275 aa)
	LOC109989687	Si:dkey-12h9.6. (645 aa)
	epm2a	EPM2A glucan phosphatase, laforin. (316 aa)
	zc3h12a	Si:dkey-206d17.12. (590 aa)
	SEC61A1	Plug_translocon domain-containing protein. (476 aa)
	LOC109983902	Plug_translocon domain-containing protein. (476 aa)
	maco1	Macoilin 1b. (687 aa)
	ENSLBEP00000018114	Macoilin 1a. (646 aa)
	rps28	Ribosomal protein S28. (53 aa)
	LOC109996790	SUN domain-containing protein. (1323 aa)
	srpra	SRP receptor subunit alpha. (651 aa)
	suco	SUN domain containing ossification factor. (1062 aa)
	sec63	SEC63 homolog, protein translocation regulator. (754 aa)
	rpl27	60S ribosomal protein L27; Belongs to the eukaryotic ribosomal protein eL27 family. (136 aa)
	ccdc47	Coiled-coil domain containing 47. (341 aa)
	sec61b	Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum. (94 aa)

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC109979846	LOC109983902	ENSLBEP00000028354	ENSLBEP00000020572	SRP receptor subunit beta.	Plug_translocon domain-containing protein.	0.724
LOC109979846	SEC61A1	ENSLBEP00000028354	ENSLBEP00000022861	SRP receptor subunit beta.	Plug_translocon domain-containing protein.	0.724
LOC109979846	rpl27	ENSLBEP00000028354	ENSLBEP00000006133	SRP receptor subunit beta.	60S ribosomal protein L27; Belongs to the eukaryotic ribosomal protein eL27 family.	0.885
LOC109979846	sec61b	ENSLBEP00000028354	ENSLBEP00000003078	SRP receptor subunit beta.	Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.	0.622
LOC109979846	sec63	ENSLBEP00000028354	ENSLBEP00000012040	SRP receptor subunit beta.	SEC63 homolog, protein translocation regulator.	0.678
LOC109979846	srpra	ENSLBEP00000028354	ENSLBEP00000012506	SRP receptor subunit beta.	SRP receptor subunit alpha.	0.998
LOC109983902	LOC109979846	ENSLBEP00000020572	ENSLBEP00000028354	Plug_translocon domain-containing protein.	SRP receptor subunit beta.	0.724
LOC109983902	RPS29	ENSLBEP00000020572	ENSLBEP00000032528	Plug_translocon domain-containing protein.	Ribosomal protein S29.	0.975
LOC109983902	ccdc47	ENSLBEP00000020572	ENSLBEP00000005782	Plug_translocon domain-containing protein.	Coiled-coil domain containing 47.	0.905
LOC109983902	rpl27	ENSLBEP00000020572	ENSLBEP00000006133	Plug_translocon domain-containing protein.	60S ribosomal protein L27; Belongs to the eukaryotic ribosomal protein eL27 family.	0.924
LOC109983902	rps28	ENSLBEP00000020572	ENSLBEP00000017564	Plug_translocon domain-containing protein.	Ribosomal protein S28.	0.798
LOC109983902	sec61b	ENSLBEP00000020572	ENSLBEP00000003078	Plug_translocon domain-containing protein.	Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.	0.994
LOC109983902	sec63	ENSLBEP00000020572	ENSLBEP00000012040	Plug_translocon domain-containing protein.	SEC63 homolog, protein translocation regulator.	0.999
LOC109983902	srpra	ENSLBEP00000020572	ENSLBEP00000012506	Plug_translocon domain-containing protein.	SRP receptor subunit alpha.	0.986
RPS29	LOC109983902	ENSLBEP00000032528	ENSLBEP00000020572	Ribosomal protein S29.	Plug_translocon domain-containing protein.	0.975
RPS29	SEC61A1	ENSLBEP00000032528	ENSLBEP00000022861	Ribosomal protein S29.	Plug_translocon domain-containing protein.	0.975
RPS29	rpl27	ENSLBEP00000032528	ENSLBEP00000006133	Ribosomal protein S29.	60S ribosomal protein L27; Belongs to the eukaryotic ribosomal protein eL27 family.	0.999
RPS29	rps28	ENSLBEP00000032528	ENSLBEP00000017564	Ribosomal protein S29.	Ribosomal protein S28.	0.999
RPS29	sec61b	ENSLBEP00000032528	ENSLBEP00000003078	Ribosomal protein S29.	Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.	0.935
SEC61A1	LOC109979846	ENSLBEP00000022861	ENSLBEP00000028354	Plug_translocon domain-containing protein.	SRP receptor subunit beta.	0.724