(16 nodes) Mismatched DNA binding network (Labrus bergylta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	msh2	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (935 aa)
	MSH2	MutS homolog 2. (600 aa)
	mlh3	MutL_C domain-containing protein. (382 aa)
	ENSLBEP00000000333	Uncharacterized protein. (270 aa)
	LOC109979207	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1148 aa)
	mlh1	MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli). (648 aa)
	msh3	MutS homolog 3 (E. coli); Component of the post-replicative DNA mismatch repair system (MMR). (1024 aa)
	msh6	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1382 aa)
	MUTYH	Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs. (536 aa)
	pms1	PMS1 homolog 1, mismatch repair system component. (1093 aa)
	ENSLBEP00000009224	MutS homolog 5. (518 aa)
	pms2	PMS1 homolog 2, mismatch repair system component. (852 aa)
	ENSLBEP00000009084	Uncharacterized protein. (88 aa)
	LOC109986017	Thymine DNA glycosylase, tandem duplicate 2. (398 aa)
	tdg	Thymine DNA glycosylase, tandem duplicate 1. (454 aa)
	msh4	MutS homolog 4. (821 aa)

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSLBEP00000000333	LOC109979207	ENSLBEP00000000333	ENSLBEP00000016612	Uncharacterized protein.	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.989
ENSLBEP00000000333	MSH2	ENSLBEP00000000333	ENSLBEP00000000272	Uncharacterized protein.	MutS homolog 2.	0.944
ENSLBEP00000000333	MUTYH	ENSLBEP00000000333	ENSLBEP00000023122	Uncharacterized protein.	Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs.	0.565
ENSLBEP00000000333	mlh1	ENSLBEP00000000333	ENSLBEP00000017339	Uncharacterized protein.	MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli).	0.992
ENSLBEP00000000333	mlh3	ENSLBEP00000000333	ENSLBEP00000000842	Uncharacterized protein.	MutL_C domain-containing protein.	0.964
ENSLBEP00000000333	msh3	ENSLBEP00000000333	ENSLBEP00000018675	Uncharacterized protein.	MutS homolog 3 (E. coli); Component of the post-replicative DNA mismatch repair system (MMR).	0.981
ENSLBEP00000000333	msh4	ENSLBEP00000000333	ENSLBEP00000003025	Uncharacterized protein.	MutS homolog 4.	0.566
ENSLBEP00000000333	msh6	ENSLBEP00000000333	ENSLBEP00000021414	Uncharacterized protein.	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.989
ENSLBEP00000000333	pms1	ENSLBEP00000000333	ENSLBEP00000037694	Uncharacterized protein.	PMS1 homolog 1, mismatch repair system component.	0.979
ENSLBEP00000000333	pms2	ENSLBEP00000000333	ENSLBEP00000012742	Uncharacterized protein.	PMS1 homolog 2, mismatch repair system component.	0.991
ENSLBEP00000009084	MUTYH	ENSLBEP00000009084	ENSLBEP00000023122	Uncharacterized protein.	Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs.	0.455
ENSLBEP00000009084	mlh1	ENSLBEP00000009084	ENSLBEP00000017339	Uncharacterized protein.	MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli).	0.954
ENSLBEP00000009084	mlh3	ENSLBEP00000009084	ENSLBEP00000000842	Uncharacterized protein.	MutL_C domain-containing protein.	0.954
ENSLBEP00000009084	msh4	ENSLBEP00000009084	ENSLBEP00000003025	Uncharacterized protein.	MutS homolog 4.	0.989
ENSLBEP00000009084	pms1	ENSLBEP00000009084	ENSLBEP00000037694	Uncharacterized protein.	PMS1 homolog 1, mismatch repair system component.	0.953
ENSLBEP00000009084	pms2	ENSLBEP00000009084	ENSLBEP00000012742	Uncharacterized protein.	PMS1 homolog 2, mismatch repair system component.	0.951
ENSLBEP00000009224	MUTYH	ENSLBEP00000009224	ENSLBEP00000023122	MutS homolog 5.	Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs.	0.455
ENSLBEP00000009224	mlh1	ENSLBEP00000009224	ENSLBEP00000017339	MutS homolog 5.	MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli).	0.962
ENSLBEP00000009224	mlh3	ENSLBEP00000009224	ENSLBEP00000000842	MutS homolog 5.	MutL_C domain-containing protein.	0.954
ENSLBEP00000009224	msh3	ENSLBEP00000009224	ENSLBEP00000018675	MutS homolog 5.	MutS homolog 3 (E. coli); Component of the post-replicative DNA mismatch repair system (MMR).	0.462