(11 nodes) V(D)J recombination network (Labrus bergylta)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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textmining

co-expression

protein homology

Your Input:
	LOC110003678	Uncharacterized protein. (363 aa)
	rag2	Recombination activating gene 2. (533 aa)
	rag1	V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1066 aa)
	LOC109992673	Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4073 aa)
	tcf7	Transcription factor 7. (386 aa)
	LOC110003486	LisH domain-containing protein. (949 aa)
	LOC109976602	LisH domain-containing protein. (949 aa)
	lef1	Lymphoid enhancer-binding factor 1. (379 aa)
	lig4	DNA ligase. (827 aa)
	atm	Non-specific serine/threonine protein kinase. (3019 aa)
	DCAF1	DDB1 and CUL4 associated factor 1. (1312 aa)

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC109992673	LOC110003678	ENSLBEP00000038443	ENSLBEP00000009882	Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.979
LOC109992673	atm	ENSLBEP00000038443	ENSLBEP00000015731	Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family.	Non-specific serine/threonine protein kinase.	0.832
LOC109992673	lig4	ENSLBEP00000038443	ENSLBEP00000018958	Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family.	DNA ligase.	0.984
LOC109992673	rag1	ENSLBEP00000038443	ENSLBEP00000001591	Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family.	V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...]	0.405
LOC109992673	rag2	ENSLBEP00000038443	ENSLBEP00000001599	Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family.	Recombination activating gene 2.	0.550
LOC110003678	LOC109992673	ENSLBEP00000009882	ENSLBEP00000038443	Uncharacterized protein.	Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family.	0.979
LOC110003678	atm	ENSLBEP00000009882	ENSLBEP00000015731	Uncharacterized protein.	Non-specific serine/threonine protein kinase.	0.474
LOC110003678	lig4	ENSLBEP00000009882	ENSLBEP00000018958	Uncharacterized protein.	DNA ligase.	0.993
atm	LOC109992673	ENSLBEP00000015731	ENSLBEP00000038443	Non-specific serine/threonine protein kinase.	Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family.	0.832
atm	LOC110003678	ENSLBEP00000015731	ENSLBEP00000009882	Non-specific serine/threonine protein kinase.	Uncharacterized protein.	0.474
atm	lig4	ENSLBEP00000015731	ENSLBEP00000018958	Non-specific serine/threonine protein kinase.	DNA ligase.	0.679
lef1	tcf7	ENSLBEP00000019554	ENSLBEP00000037034	Lymphoid enhancer-binding factor 1.	Transcription factor 7.	0.921
lig4	LOC109992673	ENSLBEP00000018958	ENSLBEP00000038443	DNA ligase.	Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family.	0.984
lig4	LOC110003678	ENSLBEP00000018958	ENSLBEP00000009882	DNA ligase.	Uncharacterized protein.	0.993
lig4	atm	ENSLBEP00000018958	ENSLBEP00000015731	DNA ligase.	Non-specific serine/threonine protein kinase.	0.679
rag1	LOC109992673	ENSLBEP00000001591	ENSLBEP00000038443	V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...]	Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family.	0.405
rag1	rag2	ENSLBEP00000001591	ENSLBEP00000001599	V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...]	Recombination activating gene 2.	0.998
rag2	LOC109992673	ENSLBEP00000001599	ENSLBEP00000038443	Recombination activating gene 2.	Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family.	0.550
rag2	rag1	ENSLBEP00000001599	ENSLBEP00000001591	Recombination activating gene 2.	V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...]	0.998
tcf7	lef1	ENSLBEP00000037034	ENSLBEP00000019554	Transcription factor 7.	Lymphoid enhancer-binding factor 1.	0.921