(20 nodes) Negative regulation of GTPase activity network (Labrus bergylta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSLBEP00000017636	Uncharacterized protein. (108 aa)
	LOC109987559	Uncharacterized protein. (281 aa)
	bcas3	BCAS3 microtubule associated cell migration factor. (859 aa)
	LOC109993297	F11 receptor, tandem duplicate 1. (319 aa)
	LOC109989254	GEM interacting protein. (1044 aa)
	LOC109982502	Cytoplasmic polyadenylation element binding protein 2. (448 aa)
	LOC109985666	TSC complex subunit 1b. (1297 aa)
	gpsm1	G protein signaling modulator 1b. (693 aa)
	bbs4	Bardet-Biedl syndrome 4. (533 aa)
	mkks	McKusick-Kaufman syndrome. (567 aa)
	arl2	ADP-ribosylation factor-like 2; Belongs to the small GTPase superfamily. Arf family. (184 aa)
	rcc2	Regulator of chromosome condensation 2. (494 aa)
	spry1	Sprouty homolog 1, antagonist of FGF signaling (Drosophila). (365 aa)
	tmed2	Transmembrane p24 trafficking protein 2. (235 aa)
	LOC109982689	SH3-domain binding protein 4. (965 aa)
	LOC109999366	SH3-domain binding protein 4a. (962 aa)
	ENSLBEP00000010675	Uncharacterized protein. (243 aa)
	ENSLBEP00000004175	Sprouty RTK signaling antagonist 2. (376 aa)
	lrrk2	Leucine-rich repeat kinase 2. (2422 aa)
	ttc8	Tetratricopeptide repeat domain 8. (505 aa)

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSLBEP00000004175	spry1	ENSLBEP00000004175	ENSLBEP00000019243	Sprouty RTK signaling antagonist 2.	Sprouty homolog 1, antagonist of FGF signaling (Drosophila).	0.785
ENSLBEP00000010675	ENSLBEP00000017636	ENSLBEP00000010675	ENSLBEP00000017636	Uncharacterized protein.	Uncharacterized protein.	0.666
ENSLBEP00000010675	bbs4	ENSLBEP00000010675	ENSLBEP00000023312	Uncharacterized protein.	Bardet-Biedl syndrome 4.	0.483
ENSLBEP00000010675	mkks	ENSLBEP00000010675	ENSLBEP00000022702	Uncharacterized protein.	McKusick-Kaufman syndrome.	0.666
ENSLBEP00000010675	ttc8	ENSLBEP00000010675	ENSLBEP00000001019	Uncharacterized protein.	Tetratricopeptide repeat domain 8.	0.483
ENSLBEP00000017636	ENSLBEP00000010675	ENSLBEP00000017636	ENSLBEP00000010675	Uncharacterized protein.	Uncharacterized protein.	0.666
ENSLBEP00000017636	LOC109985666	ENSLBEP00000017636	ENSLBEP00000026751	Uncharacterized protein.	TSC complex subunit 1b.	0.666
LOC109985666	ENSLBEP00000017636	ENSLBEP00000026751	ENSLBEP00000017636	TSC complex subunit 1b.	Uncharacterized protein.	0.666
LOC109985666	bbs4	ENSLBEP00000026751	ENSLBEP00000023312	TSC complex subunit 1b.	Bardet-Biedl syndrome 4.	0.483
LOC109985666	mkks	ENSLBEP00000026751	ENSLBEP00000022702	TSC complex subunit 1b.	McKusick-Kaufman syndrome.	0.666
LOC109985666	ttc8	ENSLBEP00000026751	ENSLBEP00000001019	TSC complex subunit 1b.	Tetratricopeptide repeat domain 8.	0.483
bbs4	ENSLBEP00000010675	ENSLBEP00000023312	ENSLBEP00000010675	Bardet-Biedl syndrome 4.	Uncharacterized protein.	0.483
bbs4	LOC109985666	ENSLBEP00000023312	ENSLBEP00000026751	Bardet-Biedl syndrome 4.	TSC complex subunit 1b.	0.483
bbs4	ttc8	ENSLBEP00000023312	ENSLBEP00000001019	Bardet-Biedl syndrome 4.	Tetratricopeptide repeat domain 8.	0.995
mkks	ENSLBEP00000010675	ENSLBEP00000022702	ENSLBEP00000010675	McKusick-Kaufman syndrome.	Uncharacterized protein.	0.666
mkks	LOC109985666	ENSLBEP00000022702	ENSLBEP00000026751	McKusick-Kaufman syndrome.	TSC complex subunit 1b.	0.666
spry1	ENSLBEP00000004175	ENSLBEP00000019243	ENSLBEP00000004175	Sprouty homolog 1, antagonist of FGF signaling (Drosophila).	Sprouty RTK signaling antagonist 2.	0.785
ttc8	ENSLBEP00000010675	ENSLBEP00000001019	ENSLBEP00000010675	Tetratricopeptide repeat domain 8.	Uncharacterized protein.	0.483
ttc8	LOC109985666	ENSLBEP00000001019	ENSLBEP00000026751	Tetratricopeptide repeat domain 8.	TSC complex subunit 1b.	0.483
ttc8	bbs4	ENSLBEP00000001019	ENSLBEP00000023312	Tetratricopeptide repeat domain 8.	Bardet-Biedl syndrome 4.	0.995