(14 nodes) Plasma lipoprotein particle remodeling network (Labrus bergylta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC109989657	Vitellogenin domain-containing protein. (789 aa)
	LOC109989500	Apolipoprotein Ba. (4238 aa)
	ENSLBEP00000021349	BPI1 domain-containing protein. (456 aa)
	lpl	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (516 aa)
	LOC109987784	PLAT domain-containing protein. (512 aa)
	lcat	Lecithin-cholesterol acyltransferase. (434 aa)
	LOC109980354	Uncharacterized protein; Belongs to the CD36 family. (430 aa)
	LOC109977272	Cholesteryl ester transfer protein; Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL; Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family. (467 aa)
	scarb1	Scavenger receptor class B, member 1; Belongs to the CD36 family. (429 aa)
	LOC110000801	Cholesteryl ester transfer protein; Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL; Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family. (474 aa)
	LOC109990367	Phospholipase A(2). (154 aa)
	ENSLBEP00000026791	Vitellogenin domain-containing protein. (736 aa)
	LOC109989658	Vitellogenin domain-containing protein. (2351 aa)
	ENSLBEP00000026611	Uncharacterized protein. (448 aa)

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSLBEP00000021349	ENSLBEP00000026611	ENSLBEP00000021349	ENSLBEP00000026611	BPI1 domain-containing protein.	Uncharacterized protein.	0.614
ENSLBEP00000021349	ENSLBEP00000026791	ENSLBEP00000021349	ENSLBEP00000026791	BPI1 domain-containing protein.	Vitellogenin domain-containing protein.	0.614
ENSLBEP00000021349	LOC109989500	ENSLBEP00000021349	ENSLBEP00000009566	BPI1 domain-containing protein.	Apolipoprotein Ba.	0.614
ENSLBEP00000021349	LOC109989657	ENSLBEP00000021349	ENSLBEP00000026580	BPI1 domain-containing protein.	Vitellogenin domain-containing protein.	0.614
ENSLBEP00000021349	LOC109989658	ENSLBEP00000021349	ENSLBEP00000026726	BPI1 domain-containing protein.	Vitellogenin domain-containing protein.	0.614
ENSLBEP00000021349	lcat	ENSLBEP00000021349	ENSLBEP00000011028	BPI1 domain-containing protein.	Lecithin-cholesterol acyltransferase.	0.457
ENSLBEP00000021349	lpl	ENSLBEP00000021349	ENSLBEP00000007852	BPI1 domain-containing protein.	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.	0.411
ENSLBEP00000026611	ENSLBEP00000021349	ENSLBEP00000026611	ENSLBEP00000021349	Uncharacterized protein.	BPI1 domain-containing protein.	0.614
ENSLBEP00000026611	ENSLBEP00000026791	ENSLBEP00000026611	ENSLBEP00000026791	Uncharacterized protein.	Vitellogenin domain-containing protein.	0.856
ENSLBEP00000026611	LOC109977272	ENSLBEP00000026611	ENSLBEP00000020928	Uncharacterized protein.	Cholesteryl ester transfer protein; Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL; Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.	0.614
ENSLBEP00000026611	LOC109980354	ENSLBEP00000026611	ENSLBEP00000013933	Uncharacterized protein.	Uncharacterized protein; Belongs to the CD36 family.	0.743
ENSLBEP00000026611	LOC109989657	ENSLBEP00000026611	ENSLBEP00000026580	Uncharacterized protein.	Vitellogenin domain-containing protein.	0.738
ENSLBEP00000026611	LOC109989658	ENSLBEP00000026611	ENSLBEP00000026726	Uncharacterized protein.	Vitellogenin domain-containing protein.	0.500
ENSLBEP00000026611	LOC110000801	ENSLBEP00000026611	ENSLBEP00000031353	Uncharacterized protein.	Cholesteryl ester transfer protein; Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL; Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.	0.614
ENSLBEP00000026611	scarb1	ENSLBEP00000026611	ENSLBEP00000037100	Uncharacterized protein.	Scavenger receptor class B, member 1; Belongs to the CD36 family.	0.743
ENSLBEP00000026791	ENSLBEP00000021349	ENSLBEP00000026791	ENSLBEP00000021349	Vitellogenin domain-containing protein.	BPI1 domain-containing protein.	0.614
ENSLBEP00000026791	ENSLBEP00000026611	ENSLBEP00000026791	ENSLBEP00000026611	Vitellogenin domain-containing protein.	Uncharacterized protein.	0.856
ENSLBEP00000026791	LOC109977272	ENSLBEP00000026791	ENSLBEP00000020928	Vitellogenin domain-containing protein.	Cholesteryl ester transfer protein; Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL; Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.	0.614
ENSLBEP00000026791	LOC109980354	ENSLBEP00000026791	ENSLBEP00000013933	Vitellogenin domain-containing protein.	Uncharacterized protein; Belongs to the CD36 family.	0.743
ENSLBEP00000026791	LOC110000801	ENSLBEP00000026791	ENSLBEP00000031353	Vitellogenin domain-containing protein.	Cholesteryl ester transfer protein; Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL; Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.	0.614