(57 nodes) Protein localization to chromosome network (Labrus bergylta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSLBEP00000032628	Uncharacterized protein. (152 aa)
	ENSLBEP00000011552	Leucine-rich repeats and WD repeat domain containing 1. (419 aa)
	ENSLBEP00000014563	ANK_REP_REGION domain-containing protein. (217 aa)
	LOC110000561	ANK_REP_REGION domain-containing protein. (569 aa)
	LOC109980951	Transcription activation suppressor b. (1827 aa)
	parp3	Poly [ADP-ribose] polymerase. (527 aa)
	kntc1	Kinetochore associated 1. (1911 aa)
	zwilch	Zwilch kinetochore protein. (595 aa)
	mau2	MAU2 sister chromatid cohesion factor. (620 aa)
	knl1	Knl1_RWD_C domain-containing protein. (1870 aa)
	bub3	BUB3 mitotic checkpoint protein. (326 aa)
	znf827	Zinc finger protein 827. (951 aa)
	ENSLBEP00000024266	Uncharacterized protein. (200 aa)
	ENSLBEP00000024280	ANK_REP_REGION domain-containing protein. (346 aa)
	ENSLBEP00000024381	Uncharacterized protein. (102 aa)
	LOC109981154	Nipped-B protein. (2473 aa)
	wapl	WAPL cohesin release factor a. (1190 aa)
	LOC109989161	Nipped-B protein. (2314 aa)
	rpa1	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (605 aa)
	mtbp	MDM2 binding protein. (737 aa)
	LOC109980924	Uncharacterized protein. (274 aa)
	ENSLBEP00000032740	Uncharacterized protein. (109 aa)
	iffo2	Intermediate filament family orphan 2b; Belongs to the intermediate filament family. (484 aa)
	bub1b	BUB1 mitotic checkpoint serine/threonine kinase Bb. (434 aa)
	atrx	ATRX chromatin remodeler. (2243 aa)
	rb1	Retinoblastoma 1. (899 aa)
	msh2	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (935 aa)
	LOC110004130	Aurora kinase B; Belongs to the protein kinase superfamily. (300 aa)
	LOC109985295	H2A histone family, member Y; Belongs to the histone H2A family. (369 aa)
	LOC109977092	Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (367 aa)
	atr	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2437 aa)
	LOC109979647	IF rod domain-containing protein. (165 aa)
	LOC109982031	Poly [ADP-ribose] polymerase. (1264 aa)
	haspin	Protein kinase domain-containing protein. (1298 aa)
	LOC110003678	Uncharacterized protein. (363 aa)
	spo11	SPO11 initiator of meiotic double stranded breaks. (390 aa)
	LOC109989819	Uncharacterized protein. (448 aa)
	ENSLBEP00000009076	Uncharacterized protein. (267 aa)
	iffo1	Intermediate filament family orphan 1b; Belongs to the intermediate filament family. (643 aa)
	ENSLBEP00000007876	Uncharacterized protein. (265 aa)
	ENSLBEP00000006873	Uncharacterized protein. (125 aa)
	ENSLBEP00000006855	HTH myb-type domain-containing protein. (181 aa)
	ENSLBEP00000005682	Uncharacterized protein. (1420 aa)
	ENSLBEP00000005132	Telo_bind domain-containing protein. (305 aa)
	ttk	Ttk protein kinase. (849 aa)
	pot1	Protection of telomeres 1 homolog. (718 aa)
	ENSLBEP00000004132	Uncharacterized protein. (94 aa)
	RPA1	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (705 aa)
	LOC109984746	Tower domain-containing protein. (922 aa)
	ENSLBEP00000002749	Uncharacterized protein. (926 aa)
	pinx1	PIN2 (TERF1) interacting telomerase inhibitor 1. (396 aa)
	LOC109988732	TERF1 (TRF1)-interacting nuclear factor 2. (557 aa)
	spdl1	Protein Spindly; Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex; Belongs to the Spindly family. (579 aa)
	ENSLBEP00000000333	Uncharacterized protein. (270 aa)
	MSH2	MutS homolog 2. (600 aa)
	mis12	MIS12 kinetochore complex component. (221 aa)
	zw10	Zw10 kinetochore protein. (767 aa)

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSLBEP00000000333	ENSLBEP00000002749	ENSLBEP00000000333	ENSLBEP00000002749	Uncharacterized protein.	Uncharacterized protein.	0.527
ENSLBEP00000000333	LOC109984746	ENSLBEP00000000333	ENSLBEP00000002832	Uncharacterized protein.	Tower domain-containing protein.	0.527
ENSLBEP00000000333	MSH2	ENSLBEP00000000333	ENSLBEP00000000272	Uncharacterized protein.	MutS homolog 2.	0.944
ENSLBEP00000000333	RPA1	ENSLBEP00000000333	ENSLBEP00000002897	Uncharacterized protein.	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.847
ENSLBEP00000000333	atr	ENSLBEP00000000333	ENSLBEP00000037854	Uncharacterized protein.	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	0.786
ENSLBEP00000000333	knl1	ENSLBEP00000000333	ENSLBEP00000021190	Uncharacterized protein.	Knl1_RWD_C domain-containing protein.	0.530
ENSLBEP00000000333	rpa1	ENSLBEP00000000333	ENSLBEP00000028522	Uncharacterized protein.	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.847
ENSLBEP00000000333	spo11	ENSLBEP00000000333	ENSLBEP00000009852	Uncharacterized protein.	SPO11 initiator of meiotic double stranded breaks.	0.493
ENSLBEP00000002749	ENSLBEP00000000333	ENSLBEP00000002749	ENSLBEP00000000333	Uncharacterized protein.	Uncharacterized protein.	0.527
ENSLBEP00000002749	ENSLBEP00000024266	ENSLBEP00000002749	ENSLBEP00000024266	Uncharacterized protein.	Uncharacterized protein.	0.725
ENSLBEP00000002749	ENSLBEP00000024280	ENSLBEP00000002749	ENSLBEP00000024280	Uncharacterized protein.	ANK_REP_REGION domain-containing protein.	0.725
ENSLBEP00000002749	LOC109984746	ENSLBEP00000002749	ENSLBEP00000002832	Uncharacterized protein.	Tower domain-containing protein.	0.897
ENSLBEP00000002749	LOC109989819	ENSLBEP00000002749	ENSLBEP00000009703	Uncharacterized protein.	Uncharacterized protein.	0.411
ENSLBEP00000002749	MSH2	ENSLBEP00000002749	ENSLBEP00000000272	Uncharacterized protein.	MutS homolog 2.	0.527
ENSLBEP00000002749	RPA1	ENSLBEP00000002749	ENSLBEP00000002897	Uncharacterized protein.	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.676
ENSLBEP00000002749	atr	ENSLBEP00000002749	ENSLBEP00000037854	Uncharacterized protein.	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	0.501
ENSLBEP00000002749	bub1b	ENSLBEP00000002749	ENSLBEP00000034348	Uncharacterized protein.	BUB1 mitotic checkpoint serine/threonine kinase Bb.	0.569
ENSLBEP00000002749	knl1	ENSLBEP00000002749	ENSLBEP00000021190	Uncharacterized protein.	Knl1_RWD_C domain-containing protein.	0.938
ENSLBEP00000002749	msh2	ENSLBEP00000002749	ENSLBEP00000035993	Uncharacterized protein.	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.527
ENSLBEP00000002749	parp3	ENSLBEP00000002749	ENSLBEP00000015495	Uncharacterized protein.	Poly [ADP-ribose] polymerase.	0.696