(25 nodes) Cellular response to heat network (Labrus bergylta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	polr2d	RPOL4c domain-containing protein. (110 aa)
	ENSLBEP00000028024	Uncharacterized protein. (264 aa)
	IER5L	Immediate early response 5-like. (298 aa)
	ENSLBEP00000027977	Translocated promoter region a, nuclear basket protein. (1601 aa)
	nf1	Neurofibromin 1b. (2672 aa)
	hikeshi	Heat shock protein nuclear import factor hikeshi. (198 aa)
	st8sia1	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1; Belongs to the glycosyltransferase 29 family. (356 aa)
	mki67	Marker of proliferation Ki-67. (1962 aa)
	bag3	BCL2 associated athanogene 3. (542 aa)
	LOC109996700	14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (257 aa)
	dhx36	DEAH (Asp-Glu-Ala-His) box polypeptide 36. (1065 aa)
	IER5L-2	Immediate early response 5 like. (293 aa)
	LOC109982952	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1. (722 aa)
	LOC109982928	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2. (736 aa)
	LOC109998952	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 2; Belongs to the 14-3-3 family. (255 aa)
	LOC110003529	Death-domain associated protein. (755 aa)
	LOC110002292	Transcriptional and immune response regulator a. (100 aa)
	ENSLBEP00000004450	Uncharacterized protein. (57 aa)
	tfec	Transcription factor EC. (460 aa)
	LOC110006071	Daxx domain-containing protein. (746 aa)
	LOC110000486	Translocated promoter region b, nuclear basket protein. (2184 aa)
	CLPB	ClpB homolog, mitochondrial AAA ATPase chaperonin. (311 aa)
	hsbp1	Heat shock factor binding protein 1a. (77 aa)
	sumo1	Small ubiquitin-related modifier. (101 aa)
	hsp90ab1	Heat shock protein 90, alpha (cytosolic), class B member 1. (725 aa)

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CLPB	LOC109982928	ENSLBEP00000037233	ENSLBEP00000031902	ClpB homolog, mitochondrial AAA ATPase chaperonin.	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2.	0.874
CLPB	LOC109982952	ENSLBEP00000037233	ENSLBEP00000031834	ClpB homolog, mitochondrial AAA ATPase chaperonin.	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1.	0.874
CLPB	hikeshi	ENSLBEP00000037233	ENSLBEP00000025553	ClpB homolog, mitochondrial AAA ATPase chaperonin.	Heat shock protein nuclear import factor hikeshi.	0.809
CLPB	hsp90ab1	ENSLBEP00000037233	ENSLBEP00000013706	ClpB homolog, mitochondrial AAA ATPase chaperonin.	Heat shock protein 90, alpha (cytosolic), class B member 1.	0.874
ENSLBEP00000004450	LOC109982928	ENSLBEP00000004450	ENSLBEP00000031902	Uncharacterized protein.	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2.	0.552
ENSLBEP00000004450	LOC109982952	ENSLBEP00000004450	ENSLBEP00000031834	Uncharacterized protein.	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1.	0.552
ENSLBEP00000004450	hsp90ab1	ENSLBEP00000004450	ENSLBEP00000013706	Uncharacterized protein.	Heat shock protein 90, alpha (cytosolic), class B member 1.	0.552
ENSLBEP00000027977	ENSLBEP00000028024	ENSLBEP00000027977	ENSLBEP00000028024	Translocated promoter region a, nuclear basket protein.	Uncharacterized protein.	0.903
ENSLBEP00000027977	sumo1	ENSLBEP00000027977	ENSLBEP00000014701	Translocated promoter region a, nuclear basket protein.	Small ubiquitin-related modifier.	0.609
ENSLBEP00000028024	ENSLBEP00000027977	ENSLBEP00000028024	ENSLBEP00000027977	Uncharacterized protein.	Translocated promoter region a, nuclear basket protein.	0.903
ENSLBEP00000028024	sumo1	ENSLBEP00000028024	ENSLBEP00000014701	Uncharacterized protein.	Small ubiquitin-related modifier.	0.609
LOC109982928	CLPB	ENSLBEP00000031902	ENSLBEP00000037233	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2.	ClpB homolog, mitochondrial AAA ATPase chaperonin.	0.874
LOC109982928	ENSLBEP00000004450	ENSLBEP00000031902	ENSLBEP00000004450	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2.	Uncharacterized protein.	0.552
LOC109982928	LOC109996700	ENSLBEP00000031902	ENSLBEP00000030736	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2.	14_3_3 domain-containing protein; Belongs to the 14-3-3 family.	0.698
LOC109982928	LOC109998952	ENSLBEP00000031902	ENSLBEP00000032771	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2.	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 2; Belongs to the 14-3-3 family.	0.698
LOC109982928	bag3	ENSLBEP00000031902	ENSLBEP00000016601	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2.	BCL2 associated athanogene 3.	0.480
LOC109982928	hsbp1	ENSLBEP00000031902	ENSLBEP00000015813	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2.	Heat shock factor binding protein 1a.	0.684
LOC109982928	hsp90ab1	ENSLBEP00000031902	ENSLBEP00000013706	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2.	Heat shock protein 90, alpha (cytosolic), class B member 1.	0.832
LOC109982952	CLPB	ENSLBEP00000031834	ENSLBEP00000037233	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1.	ClpB homolog, mitochondrial AAA ATPase chaperonin.	0.874
LOC109982952	ENSLBEP00000004450	ENSLBEP00000031834	ENSLBEP00000004450	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1.	Uncharacterized protein.	0.552