(25 nodes) Positive regulation of protein dephosphorylation network (Labrus bergylta)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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protein homology

Your Input:
	smpd1	Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (627 aa)
	ENSLBEP00000010404	Uncharacterized protein. (397 aa)
	LOC109986022	Protein phosphatase 1, regulatory subunit 15B. (568 aa)
	ambra1	Autophagy/beclin-1 regulator 1b. (1144 aa)
	cdca2	PP1-binding domain-containing protein. (875 aa)
	sympk	Symplekin. (1223 aa)
	LOC109976742	Cadherin_C domain-containing protein; Cadherins are calcium-dependent cell adhesion proteins. (192 aa)
	LOC110002047	PDZ domain-containing protein. (164 aa)
	ptprc	Protein tyrosine phosphatase receptor type C. (1151 aa)
	gba	Glucosylceramidase. (526 aa)
	ENSLBEP00000034744	PKD domain-containing protein. (261 aa)
	ankle2	Ankyrin repeat and LEM domain containing 2. (974 aa)
	vrk3	VRK serine/threonine kinase 3. (484 aa)
	cdh5	Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (787 aa)
	cnep1r1	CTD nuclear envelope phosphatase 1 regulatory subunit 1. (125 aa)
	sppl3	Signal peptide peptidase 3. (381 aa)
	ptpa	Serine/threonine-protein phosphatase 2A activator; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. (324 aa)
	ENSLBEP00000027466	PDZ domain-containing protein. (150 aa)
	LOC110002615	Uncharacterized protein. (1201 aa)
	LOC109998849	Membrane associated guanylate kinase, WW and PDZ domain containing 2a. (1316 aa)
	ppp1r7	Protein phosphatase 1, regulatory (inhibitor) subunit 7. (345 aa)
	pink1	PTEN induced kinase 1. (575 aa)
	LOC109995483	Transforming growth factor beta; Belongs to the TGF-beta family. (386 aa)
	ppp1r42	Protein phosphatase 1, regulatory subunit 42. (300 aa)
	LOC109981103	Angiotensin II receptor, type 2; Belongs to the G-protein coupled receptor 1 family. (416 aa)

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSLBEP00000027466	LOC110002615	ENSLBEP00000027466	ENSLBEP00000027222	PDZ domain-containing protein.	Uncharacterized protein.	0.579
ENSLBEP00000034744	smpd1	ENSLBEP00000034744	ENSLBEP00000016943	PKD domain-containing protein.	Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide.	0.900
LOC109976742	ptprc	ENSLBEP00000002911	ENSLBEP00000036424	Cadherin_C domain-containing protein; Cadherins are calcium-dependent cell adhesion proteins.	Protein tyrosine phosphatase receptor type C.	0.487
LOC109998849	LOC110002047	ENSLBEP00000025285	ENSLBEP00000037198	Membrane associated guanylate kinase, WW and PDZ domain containing 2a.	PDZ domain-containing protein.	0.877
LOC110002047	LOC109998849	ENSLBEP00000037198	ENSLBEP00000025285	PDZ domain-containing protein.	Membrane associated guanylate kinase, WW and PDZ domain containing 2a.	0.877
LOC110002615	ENSLBEP00000027466	ENSLBEP00000027222	ENSLBEP00000027466	Uncharacterized protein.	PDZ domain-containing protein.	0.579
ambra1	pink1	ENSLBEP00000006574	ENSLBEP00000023786	Autophagy/beclin-1 regulator 1b.	PTEN induced kinase 1.	0.468
cdh5	ptprc	ENSLBEP00000008288	ENSLBEP00000036424	Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins.	Protein tyrosine phosphatase receptor type C.	0.487
gba	smpd1	ENSLBEP00000035464	ENSLBEP00000016943	Glucosylceramidase.	Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide.	0.905
pink1	ambra1	ENSLBEP00000023786	ENSLBEP00000006574	PTEN induced kinase 1.	Autophagy/beclin-1 regulator 1b.	0.468
ptprc	LOC109976742	ENSLBEP00000036424	ENSLBEP00000002911	Protein tyrosine phosphatase receptor type C.	Cadherin_C domain-containing protein; Cadherins are calcium-dependent cell adhesion proteins.	0.487
ptprc	cdh5	ENSLBEP00000036424	ENSLBEP00000008288	Protein tyrosine phosphatase receptor type C.	Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins.	0.487
smpd1	ENSLBEP00000034744	ENSLBEP00000016943	ENSLBEP00000034744	Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide.	PKD domain-containing protein.	0.900
smpd1	gba	ENSLBEP00000016943	ENSLBEP00000035464	Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide.	Glucosylceramidase.	0.905