(23 nodes) NIK/NF-kappaB signaling network (Labrus bergylta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	tirap	Toll-interleukin 1 receptor (TIR) domain containing adaptor protein. (266 aa)
	LOC109989501	Protein kinase domain-containing protein. (505 aa)
	ENSLBEP00000010967	CARD domain-containing protein. (137 aa)
	LOC109994134	Si:ch211-113e8.10. (791 aa)
	ENSLBEP00000008955	RHD domain-containing protein. (469 aa)
	ENSLBEP00000007746	MALT paracaspase 2. (537 aa)
	LOC109993466	V-rel avian reticuloendotheliosis viral oncogene homolog A. (633 aa)
	ENSLBEP00000002780	Uncharacterized protein. (87 aa)
	LOC109993885	RHD domain-containing protein. (601 aa)
	LOC109997856	Mitogen-activated protein kinase kinase kinase 14a. (855 aa)
	LOC109991658	MALT paracaspase 1. (857 aa)
	traf4	TNF receptor-associated factor. (470 aa)
	LOC109990925	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (568 aa)
	LOC109993381	Uncharacterized protein. (627 aa)
	map3k7	Mitogen-activated protein kinase kinase kinase 7. (602 aa)
	relb	V-rel avian reticuloendotheliosis viral oncogene homolog B. (586 aa)
	ENSLBEP00000024794	Uncharacterized protein. (248 aa)
	LOC109982165	MALT paracaspase 3. (678 aa)
	LOC109975995	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (548 aa)
	LOC109998157	Uncharacterized protein; Belongs to the protein kinase superfamily. (449 aa)
	LOC110002628	Uncharacterized protein. (249 aa)
	LOC109995578	Receptor-interacting serine-threonine kinase 3. (494 aa)
	LOC109996406	ADP-ribosylation factor 2b. (1011 aa)

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSLBEP00000002780	ENSLBEP00000007746	ENSLBEP00000002780	ENSLBEP00000007746	Uncharacterized protein.	MALT paracaspase 2.	0.665
ENSLBEP00000002780	ENSLBEP00000008955	ENSLBEP00000002780	ENSLBEP00000008955	Uncharacterized protein.	RHD domain-containing protein.	0.409
ENSLBEP00000002780	LOC109975995	ENSLBEP00000002780	ENSLBEP00000023249	Uncharacterized protein.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.970
ENSLBEP00000002780	LOC109982165	ENSLBEP00000002780	ENSLBEP00000024393	Uncharacterized protein.	MALT paracaspase 3.	0.665
ENSLBEP00000002780	LOC109990925	ENSLBEP00000002780	ENSLBEP00000034805	Uncharacterized protein.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.970
ENSLBEP00000002780	LOC109991658	ENSLBEP00000002780	ENSLBEP00000034753	Uncharacterized protein.	MALT paracaspase 1.	0.665
ENSLBEP00000002780	LOC109993466	ENSLBEP00000002780	ENSLBEP00000003392	Uncharacterized protein.	V-rel avian reticuloendotheliosis viral oncogene homolog A.	0.409
ENSLBEP00000002780	LOC109993885	ENSLBEP00000002780	ENSLBEP00000030766	Uncharacterized protein.	RHD domain-containing protein.	0.409
ENSLBEP00000002780	LOC109996406	ENSLBEP00000002780	ENSLBEP00000012065	Uncharacterized protein.	ADP-ribosylation factor 2b.	0.780
ENSLBEP00000002780	LOC109997856	ENSLBEP00000002780	ENSLBEP00000030958	Uncharacterized protein.	Mitogen-activated protein kinase kinase kinase 14a.	0.780
ENSLBEP00000002780	relb	ENSLBEP00000002780	ENSLBEP00000027004	Uncharacterized protein.	V-rel avian reticuloendotheliosis viral oncogene homolog B.	0.409
ENSLBEP00000002780	tirap	ENSLBEP00000002780	ENSLBEP00000012537	Uncharacterized protein.	Toll-interleukin 1 receptor (TIR) domain containing adaptor protein.	0.635
ENSLBEP00000002780	traf4	ENSLBEP00000002780	ENSLBEP00000034790	Uncharacterized protein.	TNF receptor-associated factor.	0.558
ENSLBEP00000007746	ENSLBEP00000002780	ENSLBEP00000007746	ENSLBEP00000002780	MALT paracaspase 2.	Uncharacterized protein.	0.665
ENSLBEP00000007746	ENSLBEP00000008955	ENSLBEP00000007746	ENSLBEP00000008955	MALT paracaspase 2.	RHD domain-containing protein.	0.505
ENSLBEP00000007746	ENSLBEP00000010967	ENSLBEP00000007746	ENSLBEP00000010967	MALT paracaspase 2.	CARD domain-containing protein.	0.491
ENSLBEP00000007746	ENSLBEP00000024794	ENSLBEP00000007746	ENSLBEP00000024794	MALT paracaspase 2.	Uncharacterized protein.	0.491
ENSLBEP00000007746	LOC109975995	ENSLBEP00000007746	ENSLBEP00000023249	MALT paracaspase 2.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.897
ENSLBEP00000007746	LOC109982165	ENSLBEP00000007746	ENSLBEP00000024393	MALT paracaspase 2.	MALT paracaspase 3.	0.850
ENSLBEP00000007746	LOC109989501	ENSLBEP00000007746	ENSLBEP00000011084	MALT paracaspase 2.	Protein kinase domain-containing protein.	0.665