(35 nodes) Regulation of multicellular organism growth network (Labrus bergylta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	bcl2	BCL2 apoptosis regulator b. (229 aa)
	ppib	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (216 aa)
	LOC109999603	Growth hormone secretagogue receptor b; Belongs to the G-protein coupled receptor 1 family. (364 aa)
	ENSLBEP00000029382	DUF3496 domain-containing protein. (482 aa)
	ENSLBEP00000029399	CCDC144C domain-containing protein. (313 aa)
	igf2	Insulin-like growth factor 2b. (215 aa)
	fxn	Frataxin. (210 aa)
	LOC109983101	Signal transducer and activator of transcription. (786 aa)
	LOC110002297	Adrenoceptor beta 3a. (446 aa)
	LOC110005399	BH4_2 domain-containing protein. (194 aa)
	APP	Amyloid beta precursor protein. (646 aa)
	ENSLBEP00000037064	Uncharacterized protein. (91 aa)
	plac8	Placenta associated 8, tandem duplicate 1. (104 aa)
	adrb1	Adrenoceptor beta 1. (407 aa)
	ENSLBEP00000006058	Uncharacterized protein. (122 aa)
	ENSLBEP00000006209	Methyl-CpG binding domain protein 5. (827 aa)
	ENSLBEP00000006240	PWWP domain-containing protein. (438 aa)
	kmt5b	Lysine methyltransferase 5B. (860 aa)
	zmpste24	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (467 aa)
	socs2	Suppressor of cytokine signaling 2. (204 aa)
	ENSLBEP00000010546	Uncharacterized protein. (190 aa)
	LOC109996950	Signal transducer and activator of transcription. (730 aa)
	sgpl1	Sphingosine-1-phosphate lyase 1. (565 aa)
	LOC109980994	Colony stimulating factor 1b (macrophage). (271 aa)
	ENSLBEP00000012477	Uncharacterized protein. (203 aa)
	gpam	Glycerol-3-phosphate acyltransferase 1, mitochondrial. (827 aa)
	fto	FTO alpha-ketoglutarate dependent dioxygenase. (654 aa)
	LOC109981088	Adrenoceptor beta 2, surface a. (401 aa)
	ENSLBEP00000017636	Uncharacterized protein. (108 aa)
	LOC109994791	Signal transducer and activator of transcription. (767 aa)
	LOC109991956	TGF_BETA_2 domain-containing protein. (345 aa)
	prlh	Prolactin releasing hormone 2. (119 aa)
	smo	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (825 aa)
	mkks	McKusick-Kaufman syndrome. (567 aa)
	bbs4	Bardet-Biedl syndrome 4. (533 aa)

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APP	LOC109999603	ENSLBEP00000033207	ENSLBEP00000028027	Amyloid beta precursor protein.	Growth hormone secretagogue receptor b; Belongs to the G-protein coupled receptor 1 family.	0.502
ENSLBEP00000006209	ENSLBEP00000006240	ENSLBEP00000006209	ENSLBEP00000006240	Methyl-CpG binding domain protein 5.	PWWP domain-containing protein.	0.928
ENSLBEP00000006240	ENSLBEP00000006209	ENSLBEP00000006240	ENSLBEP00000006209	PWWP domain-containing protein.	Methyl-CpG binding domain protein 5.	0.928
ENSLBEP00000017636	ENSLBEP00000029382	ENSLBEP00000017636	ENSLBEP00000029382	Uncharacterized protein.	DUF3496 domain-containing protein.	0.452
ENSLBEP00000017636	ENSLBEP00000029399	ENSLBEP00000017636	ENSLBEP00000029399	Uncharacterized protein.	CCDC144C domain-containing protein.	0.452
ENSLBEP00000017636	fxn	ENSLBEP00000017636	ENSLBEP00000004511	Uncharacterized protein.	Frataxin.	0.569
ENSLBEP00000029382	ENSLBEP00000017636	ENSLBEP00000029382	ENSLBEP00000017636	DUF3496 domain-containing protein.	Uncharacterized protein.	0.452
ENSLBEP00000029382	ENSLBEP00000029399	ENSLBEP00000029382	ENSLBEP00000029399	DUF3496 domain-containing protein.	CCDC144C domain-containing protein.	0.917
ENSLBEP00000029382	mkks	ENSLBEP00000029382	ENSLBEP00000022702	DUF3496 domain-containing protein.	McKusick-Kaufman syndrome.	0.452
ENSLBEP00000029399	ENSLBEP00000017636	ENSLBEP00000029399	ENSLBEP00000017636	CCDC144C domain-containing protein.	Uncharacterized protein.	0.452
ENSLBEP00000029399	ENSLBEP00000029382	ENSLBEP00000029399	ENSLBEP00000029382	CCDC144C domain-containing protein.	DUF3496 domain-containing protein.	0.917
ENSLBEP00000029399	mkks	ENSLBEP00000029399	ENSLBEP00000022702	CCDC144C domain-containing protein.	McKusick-Kaufman syndrome.	0.452
ENSLBEP00000037064	prlh	ENSLBEP00000037064	ENSLBEP00000022017	Uncharacterized protein.	Prolactin releasing hormone 2.	0.839
LOC109981088	LOC110002297	ENSLBEP00000016827	ENSLBEP00000005243	Adrenoceptor beta 2, surface a.	Adrenoceptor beta 3a.	0.845
LOC109981088	adrb1	ENSLBEP00000016827	ENSLBEP00000005702	Adrenoceptor beta 2, surface a.	Adrenoceptor beta 1.	0.639
LOC109983101	LOC109994791	ENSLBEP00000005144	ENSLBEP00000017853	Signal transducer and activator of transcription.	Signal transducer and activator of transcription.	0.737
LOC109983101	socs2	ENSLBEP00000005144	ENSLBEP00000008942	Signal transducer and activator of transcription.	Suppressor of cytokine signaling 2.	0.888
LOC109994791	LOC109983101	ENSLBEP00000017853	ENSLBEP00000005144	Signal transducer and activator of transcription.	Signal transducer and activator of transcription.	0.737
LOC109994791	LOC109996950	ENSLBEP00000017853	ENSLBEP00000012203	Signal transducer and activator of transcription.	Signal transducer and activator of transcription.	0.739
LOC109994791	socs2	ENSLBEP00000017853	ENSLBEP00000008942	Signal transducer and activator of transcription.	Suppressor of cytokine signaling 2.	0.888