(6 nodes) Insulin receptor substrate binding network (Labrus bergylta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	igf1r	Tyrosine-protein kinase receptor. (1417 aa)
	LOC109987794	Tyrosine-protein kinase receptor. (1276 aa)
	grb2	Growth factor receptor bound protein 2. (230 aa)
	dcaf8	DDB1 and CUL4 associated factor 8. (625 aa)
	ENSLBEP00000016740	Recep_L_domain domain-containing protein. (281 aa)
	insr	Tyrosine-protein kinase receptor. (1364 aa)

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSLBEP00000016740	grb2	ENSLBEP00000016740	ENSLBEP00000022583	Recep_L_domain domain-containing protein.	Growth factor receptor bound protein 2.	0.895
LOC109987794	grb2	ENSLBEP00000007125	ENSLBEP00000022583	Tyrosine-protein kinase receptor.	Growth factor receptor bound protein 2.	0.895
LOC109987794	igf1r	ENSLBEP00000007125	ENSLBEP00000014965	Tyrosine-protein kinase receptor.	Tyrosine-protein kinase receptor.	0.835
grb2	ENSLBEP00000016740	ENSLBEP00000022583	ENSLBEP00000016740	Growth factor receptor bound protein 2.	Recep_L_domain domain-containing protein.	0.895
grb2	LOC109987794	ENSLBEP00000022583	ENSLBEP00000007125	Growth factor receptor bound protein 2.	Tyrosine-protein kinase receptor.	0.895
grb2	igf1r	ENSLBEP00000022583	ENSLBEP00000014965	Growth factor receptor bound protein 2.	Tyrosine-protein kinase receptor.	0.900
grb2	insr	ENSLBEP00000022583	ENSLBEP00000008641	Growth factor receptor bound protein 2.	Tyrosine-protein kinase receptor.	0.895
igf1r	LOC109987794	ENSLBEP00000014965	ENSLBEP00000007125	Tyrosine-protein kinase receptor.	Tyrosine-protein kinase receptor.	0.835
igf1r	grb2	ENSLBEP00000014965	ENSLBEP00000022583	Tyrosine-protein kinase receptor.	Growth factor receptor bound protein 2.	0.900
igf1r	insr	ENSLBEP00000014965	ENSLBEP00000008641	Tyrosine-protein kinase receptor.	Tyrosine-protein kinase receptor.	0.835
insr	grb2	ENSLBEP00000008641	ENSLBEP00000022583	Tyrosine-protein kinase receptor.	Growth factor receptor bound protein 2.	0.895
insr	igf1r	ENSLBEP00000008641	ENSLBEP00000014965	Tyrosine-protein kinase receptor.	Tyrosine-protein kinase receptor.	0.835