(68 nodes) Regulation of myeloid cell differentiation network (Labrus bergylta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	fadd	Uncharacterized protein. (192 aa)
	gabpa	GA binding protein transcription factor subunit alpha. (441 aa)
	LOC109991707	Leucine rich repeat containing 17. (457 aa)
	cib1	Calcium and integrin binding 1 (calmyrin). (189 aa)
	LOC109996314	Ribosomal protein S19. (147 aa)
	IL12B	Interleukin 12B, b. (327 aa)
	ENSLBEP00000001991	Uncharacterized protein. (528 aa)
	DCSTAMP	Dendrocyte expressed seven transmembrane protein. (502 aa)
	acin1	SAP domain-containing protein. (1393 aa)
	pithd1	PITH (C-terminal proteasome-interacting domain of thioredoxin-like) domain containing 1. (209 aa)
	LOC109988849	Mediator complex subunit 12. (2054 aa)
	LOC109995799	Uncharacterized protein; Belongs to the peptidase C14A family. (489 aa)
	LOC109995961	Uncharacterized protein; Belongs to the peptidase C14A family. (369 aa)
	LOC109983659	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a. (308 aa)
	ENSLBEP00000010546	Uncharacterized protein. (190 aa)
	meis1	Meis homeobox 1 b. (399 aa)
	tesc	Tescalcin a. (220 aa)
	LOC109980994	Colony stimulating factor 1b (macrophage). (271 aa)
	ENSLBEP00000012477	Uncharacterized protein. (203 aa)
	cdc73	Cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae). (530 aa)
	cnot4	CCR4-NOT transcription complex, subunit 4a. (796 aa)
	cd4	CD4-1 molecule. (473 aa)
	MITF	Melanocyte inducing transcription factor b. (512 aa)
	LOC109998140	C-C motif chemokine. (91 aa)
	LOC109997626	Complement C1q C chain. (235 aa)
	LOC109986726	Peroxisome proliferator-activated receptor gamma, coactivator 1 beta. (736 aa)
	fam210b	Family with sequence similarity 210 member B. (307 aa)
	mpl	MPL proto-oncogene, thrombopoietin receptor. (664 aa)
	mtor	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2492 aa)
	lef1	Lymphoid enhancer-binding factor 1. (379 aa)
	LOC109986397	CCAAT enhancer binding protein beta. (294 aa)
	LOC109975928	Uncharacterized protein; Belongs to the peptidase C14A family. (242 aa)
	ocstamp	Osteoclast stimulatory transmembrane protein. (468 aa)
	fstl3	Follistatin-like 3 (secreted glycoprotein). (250 aa)
	LOC110000655	G protein-coupled receptor 137Bb. (411 aa)
	ENSLBEP00000022120	Uncharacterized protein. (189 aa)
	ripk1	Receptor (TNFRSF)-interacting serine-threonine kinase 1, like. (683 aa)
	LOC109984320	Caspase 10, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (540 aa)
	LOC109995483	Transforming growth factor beta; Belongs to the TGF-beta family. (386 aa)
	LOC110001825	Tescalcin b. (216 aa)
	LOC109983926	GATA binding protein 1a. (421 aa)
	il34	Interleukin 34. (218 aa)
	tfe3	Transcription factor binding to IGHM enhancer 3b. (446 aa)
	LOC109976018	Uncharacterized protein. (364 aa)
	tmem64	Transmembrane protein 64. (352 aa)
	LOC114921108	Zgc:158254. (506 aa)
	LOC109983924	Melanocyte inducing transcription factor a. (377 aa)
	LOC109990356	Prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum). (494 aa)
	nf1	Neurofibromin 1b. (2672 aa)
	LOC109976537	Meis homeobox 2b. (370 aa)
	LOC109986980	TNF superfamily member 11; Belongs to the tumor necrosis factor family. (268 aa)
	ctnnbip1	Catenin, beta interacting protein 1. (81 aa)
	nfkbia	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b. (318 aa)
	TNFRSF11B	TNF receptor superfamily member 11b. (414 aa)
	tnfaip6	Tumor necrosis factor, alpha-induced protein 6. (263 aa)
	LOC110003314	Uncharacterized protein. (990 aa)
	LOC110003321	Ankyrin repeat domain 54. (324 aa)
	ankrd54	ANK_REP_REGION domain-containing protein. (179 aa)
	mturn	Maturin, neural progenitor differentiation regulator homolog (Xenopus). (129 aa)
	RPS19	Ribosomal protein S19. (152 aa)
	inpp5d	Inositol polyphosphate-5-phosphatase D. (1104 aa)
	hax1	HCLS1 associated protein X-1. (302 aa)
	hspa9	Heat shock protein 9; Belongs to the heat shock protein 70 family. (672 aa)
	rb1	Retinoblastoma 1. (899 aa)
	ctr9	CTR9 homolog, Paf1/RNA polymerase II complex component. (1139 aa)
	ENSLBEP00000036267	Transmembrane protein 178. (233 aa)
	faxdc2	Fatty acid hydroxylase domain containing 2; Belongs to the sterol desaturase family. (376 aa)
	meis2	Meis homeobox 2a. (499 aa)

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DCSTAMP	LOC109986980	ENSLBEP00000002565	ENSLBEP00000027904	Dendrocyte expressed seven transmembrane protein.	TNF superfamily member 11; Belongs to the tumor necrosis factor family.	0.535
DCSTAMP	ocstamp	ENSLBEP00000002565	ENSLBEP00000020273	Dendrocyte expressed seven transmembrane protein.	Osteoclast stimulatory transmembrane protein.	0.557
ENSLBEP00000001991	LOC109975928	ENSLBEP00000001991	ENSLBEP00000019952	Uncharacterized protein.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.426
ENSLBEP00000001991	LOC109984320	ENSLBEP00000001991	ENSLBEP00000022442	Uncharacterized protein.	Caspase 10, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.	0.426
ENSLBEP00000001991	LOC109995799	ENSLBEP00000001991	ENSLBEP00000005892	Uncharacterized protein.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.426
ENSLBEP00000001991	LOC109995961	ENSLBEP00000001991	ENSLBEP00000006015	Uncharacterized protein.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.426
ENSLBEP00000010546	cd4	ENSLBEP00000010546	ENSLBEP00000014534	Uncharacterized protein.	CD4-1 molecule.	0.475
ENSLBEP00000010546	il34	ENSLBEP00000010546	ENSLBEP00000023781	Uncharacterized protein.	Interleukin 34.	0.803
ENSLBEP00000012477	cd4	ENSLBEP00000012477	ENSLBEP00000014534	Uncharacterized protein.	CD4-1 molecule.	0.475
ENSLBEP00000012477	il34	ENSLBEP00000012477	ENSLBEP00000023781	Uncharacterized protein.	Interleukin 34.	0.803
ENSLBEP00000022120	cd4	ENSLBEP00000022120	ENSLBEP00000014534	Uncharacterized protein.	CD4-1 molecule.	0.520
ENSLBEP00000022120	mpl	ENSLBEP00000022120	ENSLBEP00000018241	Uncharacterized protein.	MPL proto-oncogene, thrombopoietin receptor.	0.940
LOC109975928	ENSLBEP00000001991	ENSLBEP00000019952	ENSLBEP00000001991	Uncharacterized protein; Belongs to the peptidase C14A family.	Uncharacterized protein.	0.426
LOC109975928	LOC109983659	ENSLBEP00000019952	ENSLBEP00000007019	Uncharacterized protein; Belongs to the peptidase C14A family.	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a.	0.446
LOC109975928	LOC109984320	ENSLBEP00000019952	ENSLBEP00000022442	Uncharacterized protein; Belongs to the peptidase C14A family.	Caspase 10, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.	0.836
LOC109975928	LOC109995961	ENSLBEP00000019952	ENSLBEP00000006015	Uncharacterized protein; Belongs to the peptidase C14A family.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.840
LOC109975928	acin1	ENSLBEP00000019952	ENSLBEP00000003175	Uncharacterized protein; Belongs to the peptidase C14A family.	SAP domain-containing protein.	0.426
LOC109975928	fadd	ENSLBEP00000019952	ENSLBEP00000028812	Uncharacterized protein; Belongs to the peptidase C14A family.	Uncharacterized protein.	0.990
LOC109975928	nfkbia	ENSLBEP00000019952	ENSLBEP00000028970	Uncharacterized protein; Belongs to the peptidase C14A family.	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b.	0.446
LOC109975928	ripk1	ENSLBEP00000019952	ENSLBEP00000022169	Uncharacterized protein; Belongs to the peptidase C14A family.	Receptor (TNFRSF)-interacting serine-threonine kinase 1, like.	0.982