(50 nodes) Positive regulation of DNA recombination network (Labrus bergylta)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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experimentally determined

Predicted Interactions

gene neighborhood

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Your Input:
	ercc2	Excision repair cross-complementation group 2. (760 aa)
	shld2	Si:ch211-134m17.9. (759 aa)
	MSH2	MutS homolog 2. (600 aa)
	ENSLBEP00000000333	Uncharacterized protein. (270 aa)
	mms19	MMS19 homolog, cytosolic iron-sulfur assembly component. (999 aa)
	LOC109989883	Enhancer of polycomb homolog. (831 aa)
	hmces	Abasic site processing protein HMCES; Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA. The HMCES DNA-protein cross- link is then degraded by the proteasome. Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endon [...] (354 aa)
	LOC109993446	AAA domain-containing protein. (835 aa)
	wdr48	WD repeat domain 48b. (669 aa)
	LOC109992925	Lysine methyltransferase 5C. (480 aa)
	ENSLBEP00000005291	Uncharacterized protein. (85 aa)
	dmap1	DNA methyltransferase 1 associated protein 1. (484 aa)
	ENSLBEP00000006016	Uncharacterized protein. (106 aa)
	kmt5b	Lysine methyltransferase 5B. (860 aa)
	mrgbp	MRG/MORF4L binding protein. (408 aa)
	LOC109995824	Uncharacterized protein. (1402 aa)
	hdgfl2	HDGF like 2. (656 aa)
	wrap53	WD repeat containing, antisense to TP53. (554 aa)
	ACTR2	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (389 aa)
	LOC109977677	Uncharacterized protein. (277 aa)
	ENSLBEP00000011876	Uncharacterized protein. (726 aa)
	tbx21	T-box transcription factor 21. (616 aa)
	LOC109979124	Helicase ATP-binding domain-containing protein. (628 aa)
	LOC109996990	CD40 molecule, TNF receptor superfamily member 5. (308 aa)
	mlh1	MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli). (648 aa)
	parp1	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1013 aa)
	ENSLBEP00000018953	Pogo transposable element derived with ZNF domain b. (1886 aa)
	ercc6	Excision repair cross-complementation group 6. (1440 aa)
	yeats4	YEATS domain containing 4. (226 aa)
	timeless	Timeless circadian clock. (1235 aa)
	tp53bp1	Tumor protein p53 binding protein, 1. (1256 aa)
	ENSLBEP00000022146	Uncharacterized protein. (82 aa)
	LOC109995483	Transforming growth factor beta; Belongs to the TGF-beta family. (386 aa)
	pias4	Protein inhibitor of activated STAT, 4a. (507 aa)
	LOC109986347	Helicase, POLQ like. (964 aa)
	LOC109992531	Enhancer of polycomb homolog. (856 aa)
	exosc3	Exosome component 3. (245 aa)
	fancb	FA complementation group B. (840 aa)
	LOC110004773	Helicase, POLQ like. (989 aa)
	rif1	Replication timing regulatory factor 1. (2650 aa)
	ENSLBEP00000032628	Uncharacterized protein. (152 aa)
	arid2	AT rich interactive domain 2 (ARID, RFX-like). (1525 aa)
	trrap	Transformation/transcription domain-associated protein; Belongs to the PI3/PI4-kinase family. (3852 aa)
	LOC109990953	Uncharacterized protein. (277 aa)
	vps72	Vacuolar protein sorting 72 homolog a. (367 aa)
	msh2	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (935 aa)
	ptprc	Protein tyrosine phosphatase receptor type C. (1151 aa)
	LOC109988738	Zgc:101810; Belongs to the actin family. (394 aa)
	LOC110002110	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (394 aa)
	LOC109979646	Uncharacterized protein. (342 aa)

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTR2	LOC109979646	ENSLBEP00000011044	ENSLBEP00000038549	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.	Uncharacterized protein.	0.405
ACTR2	LOC109988738	ENSLBEP00000011044	ENSLBEP00000037481	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.	Zgc:101810; Belongs to the actin family.	0.825
ACTR2	LOC109989883	ENSLBEP00000011044	ENSLBEP00000001674	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.	Enhancer of polycomb homolog.	0.539
ACTR2	LOC109992531	ENSLBEP00000011044	ENSLBEP00000025689	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.	Enhancer of polycomb homolog.	0.539
ACTR2	arid2	ENSLBEP00000011044	ENSLBEP00000033342	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.	AT rich interactive domain 2 (ARID, RFX-like).	0.643
ACTR2	dmap1	ENSLBEP00000011044	ENSLBEP00000005850	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.	DNA methyltransferase 1 associated protein 1.	0.714
ACTR2	ercc6	ENSLBEP00000011044	ENSLBEP00000019015	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.	Excision repair cross-complementation group 6.	0.405
ACTR2	mrgbp	ENSLBEP00000011044	ENSLBEP00000007339	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.	MRG/MORF4L binding protein.	0.442
ACTR2	trrap	ENSLBEP00000011044	ENSLBEP00000035085	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.	Transformation/transcription domain-associated protein; Belongs to the PI3/PI4-kinase family.	0.700
ACTR2	vps72	ENSLBEP00000011044	ENSLBEP00000035640	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.	Vacuolar protein sorting 72 homolog a.	0.525
ENSLBEP00000000333	LOC109979124	ENSLBEP00000000333	ENSLBEP00000014717	Uncharacterized protein.	Helicase ATP-binding domain-containing protein.	0.414
ENSLBEP00000000333	MSH2	ENSLBEP00000000333	ENSLBEP00000000272	Uncharacterized protein.	MutS homolog 2.	0.944
ENSLBEP00000000333	ercc2	ENSLBEP00000000333	ENSLBEP00000013761	Uncharacterized protein.	Excision repair cross-complementation group 2.	0.414
ENSLBEP00000000333	mlh1	ENSLBEP00000000333	ENSLBEP00000017339	Uncharacterized protein.	MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli).	0.992
ENSLBEP00000005291	LOC109979646	ENSLBEP00000005291	ENSLBEP00000038549	Uncharacterized protein.	Uncharacterized protein.	0.405
ENSLBEP00000005291	LOC109988738	ENSLBEP00000005291	ENSLBEP00000037481	Uncharacterized protein.	Zgc:101810; Belongs to the actin family.	0.826
ENSLBEP00000005291	LOC109989883	ENSLBEP00000005291	ENSLBEP00000001674	Uncharacterized protein.	Enhancer of polycomb homolog.	0.539
ENSLBEP00000005291	LOC109992531	ENSLBEP00000005291	ENSLBEP00000025689	Uncharacterized protein.	Enhancer of polycomb homolog.	0.539
ENSLBEP00000005291	arid2	ENSLBEP00000005291	ENSLBEP00000033342	Uncharacterized protein.	AT rich interactive domain 2 (ARID, RFX-like).	0.643
ENSLBEP00000005291	dmap1	ENSLBEP00000005291	ENSLBEP00000005850	Uncharacterized protein.	DNA methyltransferase 1 associated protein 1.	0.714