(42 nodes) Pigment biosynthetic process network (Labrus bergylta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	atp5if1	Uncharacterized protein. (108 aa)
	ctns	Cystinosin, lysosomal cystine transporter. (381 aa)
	urod	Uroporphyrinogen decarboxylase; Belongs to the uroporphyrinogen decarboxylase family. (368 aa)
	ENSLBEP00000011857	Iron-sulfur cluster assembly factor IBA57. (351 aa)
	mc1r	Melanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. (325 aa)
	LOC109980989	5-aminolevulinate synthase. (636 aa)
	LOC109988921	Progesterone receptor membrane component 1; Belongs to the cytochrome b5 family. (216 aa)
	LOC109990541	ATP synthase inhibitory factor subunit 1b. (107 aa)
	LOC109978902	Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. (410 aa)
	LOC109998015	Solute carrier family 25 member 39; Belongs to the mitochondrial carrier (TC 2.A.29) family. (358 aa)
	rpe65	Retinoid isomerohydrolase RPE65 a. (531 aa)
	LOC109981466	Transmembrane protein 14Cb. (106 aa)
	TYR	Tyrosinase. (562 aa)
	ENSLBEP00000019020	Uncharacterized protein. (112 aa)
	LOC109977897	Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. (218 aa)
	isca1	Iron-sulfur cluster assembly 1. (129 aa)
	tyrp1	Tyrosinase related protein 1. (513 aa)
	alas1	5-aminolevulinate synthase. (627 aa)
	LOC109990749	Cytochrome c oxidase assembly homolog 15 (yeast). (401 aa)
	LOC109999524	Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. (448 aa)
	alad	Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (343 aa)
	dct	Dopachrome tautomerase. (472 aa)
	ENSLBEP00000026048	Uncharacterized protein. (146 aa)
	fech	Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. (403 aa)
	phyhipl	Phytanoyl-CoA 2-hydroxylase interacting protein-like a. (379 aa)
	LOC109986569	Retinoid isomerohydrolase RPE65 b. (533 aa)
	cpox	Coproporphyrinogen oxidase. (443 aa)
	ENSLBEP00000005061	Porphobil_deam domain-containing protein. (173 aa)
	fxn	Frataxin. (210 aa)
	cited1	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1. (172 aa)
	tyr	Tyrosinase. (544 aa)
	alas2	5-aminolevulinate synthase. (591 aa)
	ENSLBEP00000032120	Uncharacterized protein. (364 aa)
	oca2	Oculocutaneous albinism II. (714 aa)
	LOC109996240	Premelanosome protein b. (472 aa)
	LOC110001359	D-dopachrome tautomerase. (118 aa)
	uros	Uroporphyrinogen III synthase. (267 aa)
	LOC109989791	Transmembrane protein 14Ca. (140 aa)
	ENSLBEP00000038630	Tyrosinase-related protein 1b. (512 aa)
	LOC110002125	Hydroxymethylbilane synthase. (360 aa)
	LOC109981807	Cytochrome c oxidase assembly factor heme A:farnesyltransferase COX10. (445 aa)
	LOC109997330	Transient receptor potential cation channel, subfamily C, member 1; Belongs to the transient receptor (TC 1.A.4) family. (762 aa)

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSLBEP00000005061	LOC109978902	ENSLBEP00000005061	ENSLBEP00000005929	Porphobil_deam domain-containing protein.	Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.	0.503
ENSLBEP00000005061	LOC109981807	ENSLBEP00000005061	ENSLBEP00000037229	Porphobil_deam domain-containing protein.	Cytochrome c oxidase assembly factor heme A:farnesyltransferase COX10.	0.462
ENSLBEP00000005061	LOC109990749	ENSLBEP00000005061	ENSLBEP00000021082	Porphobil_deam domain-containing protein.	Cytochrome c oxidase assembly homolog 15 (yeast).	0.431
ENSLBEP00000005061	LOC109999524	ENSLBEP00000005061	ENSLBEP00000022845	Porphobil_deam domain-containing protein.	Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.	0.503
ENSLBEP00000005061	alad	ENSLBEP00000005061	ENSLBEP00000024706	Porphobil_deam domain-containing protein.	Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.	0.993
ENSLBEP00000005061	cpox	ENSLBEP00000005061	ENSLBEP00000005234	Porphobil_deam domain-containing protein.	Coproporphyrinogen oxidase.	0.612
ENSLBEP00000005061	fech	ENSLBEP00000005061	ENSLBEP00000026900	Porphobil_deam domain-containing protein.	Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX.	0.681
ENSLBEP00000005061	isca1	ENSLBEP00000005061	ENSLBEP00000020203	Porphobil_deam domain-containing protein.	Iron-sulfur cluster assembly 1.	0.425
ENSLBEP00000005061	urod	ENSLBEP00000005061	ENSLBEP00000013839	Porphobil_deam domain-containing protein.	Uroporphyrinogen decarboxylase; Belongs to the uroporphyrinogen decarboxylase family.	0.963
ENSLBEP00000005061	uros	ENSLBEP00000005061	ENSLBEP00000033669	Porphobil_deam domain-containing protein.	Uroporphyrinogen III synthase.	0.988
ENSLBEP00000011857	LOC109981466	ENSLBEP00000011857	ENSLBEP00000017239	Iron-sulfur cluster assembly factor IBA57.	Transmembrane protein 14Cb.	0.420
ENSLBEP00000011857	LOC109989791	ENSLBEP00000011857	ENSLBEP00000033850	Iron-sulfur cluster assembly factor IBA57.	Transmembrane protein 14Ca.	0.420
ENSLBEP00000011857	fech	ENSLBEP00000011857	ENSLBEP00000026900	Iron-sulfur cluster assembly factor IBA57.	Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX.	0.482
ENSLBEP00000011857	fxn	ENSLBEP00000011857	ENSLBEP00000004511	Iron-sulfur cluster assembly factor IBA57.	Frataxin.	0.620
ENSLBEP00000011857	isca1	ENSLBEP00000011857	ENSLBEP00000020203	Iron-sulfur cluster assembly factor IBA57.	Iron-sulfur cluster assembly 1.	0.840
ENSLBEP00000019020	fech	ENSLBEP00000019020	ENSLBEP00000026900	Uncharacterized protein.	Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX.	0.588
ENSLBEP00000026048	ENSLBEP00000038630	ENSLBEP00000026048	ENSLBEP00000038630	Uncharacterized protein.	Tyrosinase-related protein 1b.	0.841
ENSLBEP00000026048	dct	ENSLBEP00000026048	ENSLBEP00000026039	Uncharacterized protein.	Dopachrome tautomerase.	0.846
ENSLBEP00000026048	mc1r	ENSLBEP00000026048	ENSLBEP00000010275	Uncharacterized protein.	Melanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family.	0.574
ENSLBEP00000026048	oca2	ENSLBEP00000026048	ENSLBEP00000033092	Uncharacterized protein.	Oculocutaneous albinism II.	0.562