(43 nodes) Positive regulation of Ras protein signal transduction network (Labrus bergylta)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	shoc2	SHOC2 leucine rich repeat scaffold protein. (582 aa)
	LOC109997871	Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1072 aa)
	gpr18	G protein-coupled receptor 18. (412 aa)
	LOC109994972	G protein-coupled receptor 20; Belongs to the G-protein coupled receptor 1 family. (389 aa)
	LOC109994937	Actin binding Rho activating protein b. (338 aa)
	LOC109996670	Coagulation factor II (thrombin) receptor-like 2. (367 aa)
	p2ry8	P2Y receptor family member 8; Belongs to the G-protein coupled receptor 1 family. (346 aa)
	LOC109998346	Actin binding Rho activating protein a. (356 aa)
	lpar1	Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (353 aa)
	LOC110000146	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (405 aa)
	ENSLBEP00000024286	G_PROTEIN_RECEP_F1_2 domain-containing protein. (340 aa)
	GPR55	G protein-coupled receptor 55; Belongs to the G-protein coupled receptor 1 family. (311 aa)
	ENSLBEP00000020592	Uncharacterized protein. (218 aa)
	LOC109981081	Lysophosphatidic acid receptor 4; Belongs to the G-protein coupled receptor 1 family. (354 aa)
	LOC109981038	P2Y receptor family member 10. (386 aa)
	GPR174	G protein-coupled receptor 174. (387 aa)
	LOC109977175	Costars domain-containing protein. (358 aa)
	ENSLBEP00000017406	Si:dkey-33o22.1. (90 aa)
	LOC109985267	Lysophosphatidic acid receptor 6b; Belongs to the G-protein coupled receptor 1 family. (358 aa)
	arhgef3	Rho guanine nucleotide exchange factor (GEF) 3. (486 aa)
	LOC109999093	Coagulation factor II (thrombin) receptor-like 1, tandem duplicate 2. (383 aa)
	ENSLBEP00000036195	Coagulation factor II (thrombin) receptor-like 1, tandem duplicate 1. (363 aa)
	F2RL2	Coagulation factor II thrombin receptor like 2. (380 aa)
	lrrc59	Leucine rich repeat containing 59. (323 aa)
	LOC109993347	Lysophosphatidic acid receptor 6a; Belongs to the G-protein coupled receptor 1 family. (356 aa)
	LOC109984577	Neuroepithelial cell transforming 1. (618 aa)
	LOC110006262	Lysophosphatidic acid receptor 5b. (288 aa)
	LOC109991911	Uncharacterized protein. (261 aa)
	ENSLBEP00000014490	G_PROTEIN_RECEP_F1_2 domain-containing protein. (298 aa)
	ENSLBEP00000035948	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (331 aa)
	gpr17	G protein-coupled receptor 17. (338 aa)
	stk19	Serine/threonine kinase 19. (262 aa)
	LOC109993297	F11 receptor, tandem duplicate 1. (319 aa)
	ENSLBEP00000002206	G_PROTEIN_RECEP_F1_2 domain-containing protein. (273 aa)
	f2rl3	F2R like thrombin or trypsin receptor 3; Belongs to the G-protein coupled receptor 1 family. (383 aa)
	ENSLBEP00000014473	Lysophosphatidic acid receptor 5b. (302 aa)
	LOC109987186	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1002 aa)
	NET1	Uncharacterized protein. (577 aa)
	ENSLBEP00000012477	Uncharacterized protein. (203 aa)
	LOC109980994	Colony stimulating factor 1b (macrophage). (271 aa)
	rtn4r	Reticulon 4 receptor. (466 aa)
	ENSLBEP00000010546	Uncharacterized protein. (190 aa)
	ENSLBEP00000009828	Si:dkey-29b11.3. (83 aa)

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSLBEP00000002206	LOC109987186	ENSLBEP00000002206	ENSLBEP00000013894	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.518
ENSLBEP00000002206	LOC109997871	ENSLBEP00000002206	ENSLBEP00000031835	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma; Belongs to the PI3/PI4-kinase family.	0.518
ENSLBEP00000002206	f2rl3	ENSLBEP00000002206	ENSLBEP00000032115	G_PROTEIN_RECEP_F1_2 domain-containing protein.	F2R like thrombin or trypsin receptor 3; Belongs to the G-protein coupled receptor 1 family.	0.656
ENSLBEP00000002206	gpr18	ENSLBEP00000002206	ENSLBEP00000029809	G_PROTEIN_RECEP_F1_2 domain-containing protein.	G protein-coupled receptor 18.	0.536
ENSLBEP00000002206	lpar1	ENSLBEP00000002206	ENSLBEP00000028125	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family.	0.715
ENSLBEP00000014473	LOC109987186	ENSLBEP00000014473	ENSLBEP00000013894	Lysophosphatidic acid receptor 5b.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.518
ENSLBEP00000014473	LOC109997871	ENSLBEP00000014473	ENSLBEP00000031835	Lysophosphatidic acid receptor 5b.	Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma; Belongs to the PI3/PI4-kinase family.	0.518
ENSLBEP00000014473	f2rl3	ENSLBEP00000014473	ENSLBEP00000032115	Lysophosphatidic acid receptor 5b.	F2R like thrombin or trypsin receptor 3; Belongs to the G-protein coupled receptor 1 family.	0.656
ENSLBEP00000014473	gpr18	ENSLBEP00000014473	ENSLBEP00000029809	Lysophosphatidic acid receptor 5b.	G protein-coupled receptor 18.	0.536
ENSLBEP00000014473	lpar1	ENSLBEP00000014473	ENSLBEP00000028125	Lysophosphatidic acid receptor 5b.	Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family.	0.800
ENSLBEP00000014490	LOC109987186	ENSLBEP00000014490	ENSLBEP00000013894	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.518
ENSLBEP00000014490	LOC109997871	ENSLBEP00000014490	ENSLBEP00000031835	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma; Belongs to the PI3/PI4-kinase family.	0.518
ENSLBEP00000014490	f2rl3	ENSLBEP00000014490	ENSLBEP00000032115	G_PROTEIN_RECEP_F1_2 domain-containing protein.	F2R like thrombin or trypsin receptor 3; Belongs to the G-protein coupled receptor 1 family.	0.656
ENSLBEP00000014490	gpr18	ENSLBEP00000014490	ENSLBEP00000029809	G_PROTEIN_RECEP_F1_2 domain-containing protein.	G protein-coupled receptor 18.	0.536
ENSLBEP00000014490	lpar1	ENSLBEP00000014490	ENSLBEP00000028125	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family.	0.800
ENSLBEP00000024286	LOC109987186	ENSLBEP00000024286	ENSLBEP00000013894	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.518
ENSLBEP00000024286	LOC109997871	ENSLBEP00000024286	ENSLBEP00000031835	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma; Belongs to the PI3/PI4-kinase family.	0.518
ENSLBEP00000024286	f2rl3	ENSLBEP00000024286	ENSLBEP00000032115	G_PROTEIN_RECEP_F1_2 domain-containing protein.	F2R like thrombin or trypsin receptor 3; Belongs to the G-protein coupled receptor 1 family.	0.656
ENSLBEP00000024286	gpr18	ENSLBEP00000024286	ENSLBEP00000029809	G_PROTEIN_RECEP_F1_2 domain-containing protein.	G protein-coupled receptor 18.	0.536
ENSLBEP00000024286	lpar1	ENSLBEP00000024286	ENSLBEP00000028125	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family.	0.800