(48 nodes) Axon extension network (Labrus bergylta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC109999320	Sema domain-containing protein. (1092 aa)
	SRF	Serum response factor. (278 aa)
	ulk1	Unc-51 like autophagy activating kinase 1. (1019 aa)
	srf	Serum response factor b. (526 aa)
	LOC109986709	Slit homolog 3 (Drosophila). (1430 aa)
	LOC110002886	Slit homolog 2 (Drosophila). (1465 aa)
	ENSLBEP00000017406	Si:dkey-33o22.1. (90 aa)
	sema5a	Sema domain-containing protein. (1078 aa)
	LOC110003002	Uncharacterized protein; Belongs to the semaphorin family. (592 aa)
	sema7a	Semaphorin 7A; Belongs to the semaphorin family. (606 aa)
	LOC109990259	Endothelin 1. (196 aa)
	SPAST	Spastin; Belongs to the AAA ATPase family. (462 aa)
	LOC110002537	Vinculin a. (596 aa)
	LOC109984747	Doublecortin-like kinase 1b. (752 aa)
	LOC109987072	Endothelin 2. (219 aa)
	ubap1	Ubiquitin associated protein 1. (465 aa)
	ednra	Endothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family. (447 aa)
	LOC109975235	Sema domain-containing protein; Belongs to the semaphorin family. (465 aa)
	LOC109986856	Myosin IXAa; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2207 aa)
	LOC109988217	Slit homolog 1b (Drosophila). (1474 aa)
	thsd7a	Thrombospondin, type I, domain containing 7Aa. (1583 aa)
	ryk	Receptor like tyrosine kinase. (630 aa)
	mycbp2	MYC binding protein 2. (4537 aa)
	LOC110001396	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family. (464 aa)
	fam53b	Family with sequence similarity 53 member B. (413 aa)
	raph1	Ras association (RalGDS/AF-6) and pleckstrin homology domains 1b. (570 aa)
	LOC109983354	Unc-51 like autophagy activating kinase 1a. (917 aa)
	LOC109996721	Slit homolog 1a (Drosophila). (1384 aa)
	cyfip1	Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa)
	LOC110000785	Spastin; ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Required for membrane traffic from the endoplasmic reticulum (ER) to the Go [...] (553 aa)
	LOC109986946	Uncharacterized protein. (564 aa)
	LOC109996690	Survival of motor neuron 1, telomeric. (284 aa)
	FAM53B	Uncharacterized protein. (446 aa)
	LOC109980617	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fa; Belongs to the semaphorin family. (789 aa)
	dclk1	Doublecortin-like kinase 1a. (722 aa)
	c9orf72	Zgc:100846. (462 aa)
	LOC110002606	Si:ch211-113g11.6; Belongs to the semaphorin family. (488 aa)
	LOC110005162	Myosin IXAb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2388 aa)
	LOC109983903	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fb; Belongs to the semaphorin family. (701 aa)
	ssna1	Sjogren syndrome nuclear autoantigen 1. (112 aa)
	dcx	Uncharacterized protein. (346 aa)
	ENSLBEP00000003753	Uncharacterized protein. (481 aa)
	ENSLBEP00000004382	LRRNT domain-containing protein. (166 aa)
	vcl	Vinculin. (1066 aa)
	spg11	SPG11 vesicle trafficking associated, spatacsin. (2367 aa)
	sema5b	Sema domain-containing protein. (1015 aa)
	ENSLBEP00000010466	Uncharacterized protein. (61 aa)
	ulk2	Unc-51 like autophagy activating kinase 2. (1030 aa)

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSLBEP00000004382	LOC109986709	ENSLBEP00000004382	ENSLBEP00000014642	LRRNT domain-containing protein.	Slit homolog 3 (Drosophila).	0.597
ENSLBEP00000004382	LOC109986856	ENSLBEP00000004382	ENSLBEP00000023664	LRRNT domain-containing protein.	Myosin IXAa; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.528
ENSLBEP00000004382	LOC110002886	ENSLBEP00000004382	ENSLBEP00000015647	LRRNT domain-containing protein.	Slit homolog 2 (Drosophila).	0.823
ENSLBEP00000004382	LOC110005162	ENSLBEP00000004382	ENSLBEP00000025910	LRRNT domain-containing protein.	Myosin IXAb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.528
ENSLBEP00000010466	LOC109986946	ENSLBEP00000010466	ENSLBEP00000030898	Uncharacterized protein.	Uncharacterized protein.	0.560
ENSLBEP00000010466	raph1	ENSLBEP00000010466	ENSLBEP00000033748	Uncharacterized protein.	Ras association (RalGDS/AF-6) and pleckstrin homology domains 1b.	0.560
ENSLBEP00000010466	vcl	ENSLBEP00000010466	ENSLBEP00000005597	Uncharacterized protein.	Vinculin.	0.719
LOC109983354	c9orf72	ENSLBEP00000032915	ENSLBEP00000027165	Unc-51 like autophagy activating kinase 1a.	Zgc:100846.	0.937
LOC109983354	ulk2	ENSLBEP00000032915	ENSLBEP00000010749	Unc-51 like autophagy activating kinase 1a.	Unc-51 like autophagy activating kinase 2.	0.842
LOC109984747	dclk1	ENSLBEP00000003571	ENSLBEP00000027362	Doublecortin-like kinase 1b.	Doublecortin-like kinase 1a.	0.661
LOC109984747	dcx	ENSLBEP00000003571	ENSLBEP00000003590	Doublecortin-like kinase 1b.	Uncharacterized protein.	0.830
LOC109986709	ENSLBEP00000004382	ENSLBEP00000014642	ENSLBEP00000004382	Slit homolog 3 (Drosophila).	LRRNT domain-containing protein.	0.597
LOC109986709	LOC109986856	ENSLBEP00000014642	ENSLBEP00000023664	Slit homolog 3 (Drosophila).	Myosin IXAa; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.528
LOC109986709	LOC110005162	ENSLBEP00000014642	ENSLBEP00000025910	Slit homolog 3 (Drosophila).	Myosin IXAb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.528
LOC109986856	ENSLBEP00000004382	ENSLBEP00000023664	ENSLBEP00000004382	Myosin IXAa; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	LRRNT domain-containing protein.	0.528
LOC109986856	LOC109986709	ENSLBEP00000023664	ENSLBEP00000014642	Myosin IXAa; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Slit homolog 3 (Drosophila).	0.528
LOC109986856	LOC109988217	ENSLBEP00000023664	ENSLBEP00000038274	Myosin IXAa; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Slit homolog 1b (Drosophila).	0.528
LOC109986856	LOC109996690	ENSLBEP00000023664	ENSLBEP00000029881	Myosin IXAa; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Survival of motor neuron 1, telomeric.	0.405
LOC109986856	LOC109996721	ENSLBEP00000023664	ENSLBEP00000032630	Myosin IXAa; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Slit homolog 1a (Drosophila).	0.528
LOC109986856	LOC110002886	ENSLBEP00000023664	ENSLBEP00000015647	Myosin IXAa; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Slit homolog 2 (Drosophila).	0.528