(77 nodes) Presynaptic active zone network (Labrus bergylta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	P2RY4	Pyrimidinergic receptor P2Y4; Belongs to the G-protein coupled receptor 1 family. (344 aa)
	ppfia1	PTPRF interacting protein alpha 1. (1242 aa)
	LOC109984025	Unc-13 homolog A. (1562 aa)
	RIMS2	Regulating synaptic membrane exocytosis 2. (1648 aa)
	rims3	Regulating synaptic membrane exocytosis 3. (324 aa)
	LOC109990778	PPFIA binding protein 2a. (823 aa)
	pnisr	PNN-interacting serine/arginine-rich protein. (835 aa)
	LOC109978841	Laminin N-terminal domain-containing protein. (314 aa)
	LOC109998004	PTPRF interacting protein alpha 3. (1237 aa)
	LOC109993531	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (448 aa)
	LOC109977797	Syntaxin 11a; Belongs to the syntaxin family. (293 aa)
	LOC109978224	t-SNARE coiled-coil homology domain-containing protein. (294 aa)
	zzef1	Zinc finger, ZZ-type with EF hand domain 1. (2851 aa)
	c1qbp	Complement component 1, q subcomponent binding protein. (288 aa)
	ctbp1	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (443 aa)
	LOC109987127	Aa_trans domain-containing protein. (522 aa)
	ENSLBEP00000011274	SAM domain-containing protein. (257 aa)
	erc1	ELKS/RAB6-interacting/CAST family member 1a. (1133 aa)
	nufip1	C2H2-type domain-containing protein. (474 aa)
	stx3	Syntaxin 3A; Belongs to the syntaxin family. (294 aa)
	LOC109995936	Syntaxin 4; Belongs to the syntaxin family. (297 aa)
	UNC13C	Unc-13 homolog C. (2098 aa)
	nptn	Neuroplastin b. (394 aa)
	ENSLBEP00000014949	Uncharacterized protein. (181 aa)
	ppfia4	PTPRF interacting protein alpha 4. (1188 aa)
	ENSLBEP00000016144	Uncharacterized protein. (65 aa)
	ENSLBEP00000016420	Aa_trans domain-containing protein. (547 aa)
	LOC109986243	Solute carrier family 32 member 1. (526 aa)
	ENSLBEP00000017238	GALANIN domain-containing protein. (156 aa)
	LOC109994200	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1166 aa)
	LOC110003082	Uncharacterized protein. (380 aa)
	LOC110004274	Si:ch73-330k17.3. (221 aa)
	LOC109983245	Otoferlin a. (2032 aa)
	LOC109998683	Piccolo presynaptic cytomatrix protein a. (2621 aa)
	ENSLBEP00000019157	Uncharacterized protein. (83 aa)
	ENSLBEP00000019383	Uncharacterized protein. (104 aa)
	ENSLBEP00000019755	Uncharacterized protein. (274 aa)
	LOC109998029	ELKS/RAB6-interacting/CAST family member 1. (1188 aa)
	LOC109975356	Vav 3 guanine nucleotide exchange factor b. (456 aa)
	LOC109989134	Netrin g2a. (579 aa)
	ENSLBEP00000021028	SynN domain-containing protein. (193 aa)
	LOC109989139	Uncharacterized protein. (1460 aa)
	RIMS1	Regulating synaptic membrane exocytosis 1. (1422 aa)
	ENSLBEP00000023069	Uncharacterized protein. (86 aa)
	LOC109982784	Uncharacterized protein. (1584 aa)
	cplx3	Complexin 3b. (156 aa)
	CDH2	Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins. (910 aa)
	LOC109988478	Zgc:172282. (693 aa)
	erc2	ELKS/RAB6-interacting/CAST family member 2. (1152 aa)
	LOC109990294	Bassoon (presynaptic cytomatrix protein) b. (3089 aa)
	LOC110003064	t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family. (257 aa)
	LOC109996638	Uncharacterized protein. (3694 aa)
	STX11	Syntaxin 11; Belongs to the syntaxin family. (300 aa)
	LOC109996130	Uncharacterized protein. (1147 aa)
	LOC109998863	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1107 aa)
	LOC110002613	Syntaxin 1B; Belongs to the syntaxin family. (302 aa)
	vps11	Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family. (926 aa)
	fer1l6	Fer-1 like family member 6. (1740 aa)
	unc13b	Uncharacterized protein. (1546 aa)
	ENSLBEP00000028806	PPFIA binding protein 1a. (325 aa)
	LOC109985770	Syntaxin 1A (brain); Belongs to the syntaxin family. (323 aa)
	PCLO	Piccolo presynaptic cytomatrix protein. (4666 aa)
	LOC109987906	Uncharacterized protein. (1160 aa)
	ENSLBEP00000031587	C2 domain-containing protein. (276 aa)
	LOC109984480	Netrin G2. (633 aa)
	LOC109993917	Uncharacterized protein. (1240 aa)
	LOC109983340	Syntaxin 2b; Belongs to the syntaxin family. (293 aa)
	ntng1	Netrin g1a. (546 aa)
	APP	Amyloid beta precursor protein. (646 aa)
	ctbp2	Uncharacterized protein. (988 aa)
	ppfia2	PTPRF interacting protein alpha 2. (1267 aa)
	PPFIA3	PTPRF interacting protein alpha 3. (1230 aa)
	STX19	Syntaxin 19. (302 aa)
	CDH2-2	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (915 aa)
	nectin1	Nectin cell adhesion molecule 1b. (499 aa)
	LOC110002092	Si:ch211-132f19.7; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1154 aa)
	LOC109992772	Uncharacterized protein. (1065 aa)

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDH2	CDH2-2	ENSLBEP00000023804	ENSLBEP00000037704	Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.840
CDH2-2	CDH2	ENSLBEP00000037704	ENSLBEP00000023804	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins.	0.840
ENSLBEP00000011274	ENSLBEP00000016144	ENSLBEP00000011274	ENSLBEP00000016144	SAM domain-containing protein.	Uncharacterized protein.	0.746
ENSLBEP00000011274	LOC109998004	ENSLBEP00000011274	ENSLBEP00000006414	SAM domain-containing protein.	PTPRF interacting protein alpha 3.	0.746
ENSLBEP00000011274	PPFIA3	ENSLBEP00000011274	ENSLBEP00000034296	SAM domain-containing protein.	PTPRF interacting protein alpha 3.	0.746
ENSLBEP00000011274	ppfia1	ENSLBEP00000011274	ENSLBEP00000001399	SAM domain-containing protein.	PTPRF interacting protein alpha 1.	0.746
ENSLBEP00000011274	ppfia2	ENSLBEP00000011274	ENSLBEP00000034237	SAM domain-containing protein.	PTPRF interacting protein alpha 2.	0.746
ENSLBEP00000011274	ppfia4	ENSLBEP00000011274	ENSLBEP00000015719	SAM domain-containing protein.	PTPRF interacting protein alpha 4.	0.746
ENSLBEP00000016144	ENSLBEP00000011274	ENSLBEP00000016144	ENSLBEP00000011274	Uncharacterized protein.	SAM domain-containing protein.	0.746
ENSLBEP00000016144	ENSLBEP00000017238	ENSLBEP00000016144	ENSLBEP00000017238	Uncharacterized protein.	GALANIN domain-containing protein.	0.746
ENSLBEP00000016144	ENSLBEP00000019157	ENSLBEP00000016144	ENSLBEP00000019157	Uncharacterized protein.	Uncharacterized protein.	0.433
ENSLBEP00000016144	ENSLBEP00000019383	ENSLBEP00000016144	ENSLBEP00000019383	Uncharacterized protein.	Uncharacterized protein.	0.746
ENSLBEP00000016144	ENSLBEP00000019755	ENSLBEP00000016144	ENSLBEP00000019755	Uncharacterized protein.	Uncharacterized protein.	0.474
ENSLBEP00000016144	ENSLBEP00000021028	ENSLBEP00000016144	ENSLBEP00000021028	Uncharacterized protein.	SynN domain-containing protein.	0.433
ENSLBEP00000016144	ENSLBEP00000028806	ENSLBEP00000016144	ENSLBEP00000028806	Uncharacterized protein.	PPFIA binding protein 1a.	0.746
ENSLBEP00000016144	ENSLBEP00000031587	ENSLBEP00000016144	ENSLBEP00000031587	Uncharacterized protein.	C2 domain-containing protein.	0.901
ENSLBEP00000016144	LOC109977797	ENSLBEP00000016144	ENSLBEP00000006775	Uncharacterized protein.	Syntaxin 11a; Belongs to the syntaxin family.	0.441
ENSLBEP00000016144	LOC109978224	ENSLBEP00000016144	ENSLBEP00000006794	Uncharacterized protein.	t-SNARE coiled-coil homology domain-containing protein.	0.441
ENSLBEP00000016144	LOC109982784	ENSLBEP00000016144	ENSLBEP00000023407	Uncharacterized protein.	Uncharacterized protein.	0.632
ENSLBEP00000016144	LOC109983340	ENSLBEP00000016144	ENSLBEP00000032804	Uncharacterized protein.	Syntaxin 2b; Belongs to the syntaxin family.	0.433