(78 nodes) Epithelial cell proliferation network (Labrus bergylta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC109975478	Cytochrome P450, family 7, subfamily B, polypeptide 1. (537 aa)
	LOC109987057	Keratinocyte differentiation factor 1b. (370 aa)
	ehf	Ets homologous factor. (274 aa)
	tgfa	Transforming growth factor, alpha. (254 aa)
	scarb1	Scavenger receptor class B, member 1; Belongs to the CD36 family. (429 aa)
	amotl2	Angiomotin like 2a. (699 aa)
	rb1	Retinoblastoma 1. (899 aa)
	cunh6orf89	Zgc:162255. (332 aa)
	LOC109985163	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (992 aa)
	LOC109982488	Uncharacterized protein. (223 aa)
	LOC110000815	Vascular endothelial growth factor Aa; Belongs to the PDGF/VEGF growth factor family. (188 aa)
	ENSLBEP00000031721	Lysyl oxidase-like 4. (265 aa)
	ENSLBEP00000031755	Lysyl oxidase-like 4. (415 aa)
	LOC109997239	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (390 aa)
	LOC110001293	Fibrinogen C-terminal domain-containing protein. (349 aa)
	bax	BCL2 associated X, apoptosis regulator a. (192 aa)
	CCN3	Cellular communication network factor 3. (350 aa)
	ENSLBEP00000030423	EGF-like domain-containing protein. (173 aa)
	nkx2-5	NK2 homeobox 5. (315 aa)
	ift80	Intraflagellar transport 80 homolog (Chlamydomonas). (775 aa)
	LOC109998896	Zgc:153993. (205 aa)
	LOC109998905	Uncharacterized protein. (204 aa)
	ENSLBEP00000027960	Uncharacterized protein. (102 aa)
	LOC109986980	TNF superfamily member 11; Belongs to the tumor necrosis factor family. (268 aa)
	nf1	Neurofibromin 1b. (2672 aa)
	LOC110001197	BMP binding endothelial regulator. (651 aa)
	st8sia1	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1; Belongs to the glycosyltransferase 29 family. (356 aa)
	LOC109991455	Angiomotin like 2b. (704 aa)
	IGFBP3	Insulin like growth factor binding protein 3. (289 aa)
	LOC109993761	Prokineticin 2. (106 aa)
	pdx1	Pancreatic and duodenal homeobox 1. (257 aa)
	sav1	Salvador family WW domain containing protein 1. (400 aa)
	LOC109995483	Transforming growth factor beta; Belongs to the TGF-beta family. (386 aa)
	prkx	Protein kinase X-linked; Belongs to the protein kinase superfamily. (372 aa)
	smo	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (825 aa)
	stk11	Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (438 aa)
	ENSLBEP00000022374	Uncharacterized protein. (194 aa)
	flcn	Folliculin. (559 aa)
	IGFBP4	Insulin like growth factor binding protein 4. (242 aa)
	phox2b	Paired like homeobox 2Bb. (286 aa)
	bad	BCL2 associated agonist of cell death b. (221 aa)
	ENSLBEP00000020423	Prokineticin 1. (117 aa)
	LOC109986397	CCAAT enhancer binding protein beta. (294 aa)
	LOC109984299	Fibrinogen C-terminal domain-containing protein. (299 aa)
	mki67	Marker of proliferation Ki-67. (1962 aa)
	LOC110005100	Short chain dehydrogenase/reductase family 16C, member 5a; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (300 aa)
	ppard	Peroxisome proliferator-activated receptor delta b. (510 aa)
	LOC109981070	Uncharacterized protein. (662 aa)
	LOC109990195	Insulin-like growth factor binding protein 5a. (266 aa)
	wnt16	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
	sdr16c5	Short chain dehydrogenase/reductase family 16C, member 5a. (531 aa)
	LOC110005072	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (337 aa)
	itgb1bp1	Integrin beta 1 binding protein 1. (200 aa)
	lmo2	LIM domain only 2 (rhombotin-like 1). (161 aa)
	LOC109978280	Prokineticin 1. (106 aa)
	wdr77	WD_REPEATS_REGION domain-containing protein. (334 aa)
	LOC109991911	Uncharacterized protein. (261 aa)
	LOC109980354	Uncharacterized protein; Belongs to the CD36 family. (430 aa)
	hlx	H2.0-like homeo box 1 (Drosophila). (358 aa)
	ift52	Intraflagellar transport 52 homolog (Chlamydomonas). (423 aa)
	wnt2b	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (391 aa)
	bmpr2	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1041 aa)
	ift74	Intraflagellar transport 74. (604 aa)
	xbp1	X-box binding protein 1. (264 aa)
	prok1	Prokineticin 1. (136 aa)
	LOC109999203	Si:cabz01100188.1. (894 aa)
	NKX2-8	NK2 homeobox 8. (223 aa)
	kdf1	Keratinocyte differentiation factor 1a. (404 aa)
	LOC109996916	ELL associated factor 2. (274 aa)
	LOC109981436	Uncharacterized protein. (790 aa)
	igfbp5	Insulin-like growth factor binding protein 5a. (268 aa)
	LOC110001654	NK3 homeobox 1. (191 aa)
	fgf7	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (202 aa)
	NCSTN	Nicastrin. (701 aa)
	nrarp	NOTCH regulated ankyrin repeat protein a. (112 aa)
	ENSLBEP00000005272	Uncharacterized protein. (339 aa)
	LOC110004290	EAF domain-containing protein. (273 aa)
	wnt2	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (350 aa)

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

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structured XML interaction data, according to the 'PSI-MI' data standard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSLBEP00000005272	LOC109981070	ENSLBEP00000005272	ENSLBEP00000018998	Uncharacterized protein.	Uncharacterized protein.	0.852
ENSLBEP00000005272	LOC110001654	ENSLBEP00000005272	ENSLBEP00000006731	Uncharacterized protein.	NK3 homeobox 1.	0.525
ENSLBEP00000005272	prkx	ENSLBEP00000005272	ENSLBEP00000022556	Uncharacterized protein.	Protein kinase X-linked; Belongs to the protein kinase superfamily.	0.644
ENSLBEP00000005272	rb1	ENSLBEP00000005272	ENSLBEP00000035832	Uncharacterized protein.	Retinoblastoma 1.	0.498
ENSLBEP00000005272	wdr77	ENSLBEP00000005272	ENSLBEP00000016548	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.420
ENSLBEP00000022374	bad	ENSLBEP00000022374	ENSLBEP00000021080	Uncharacterized protein.	BCL2 associated agonist of cell death b.	0.886
ENSLBEP00000022374	bax	ENSLBEP00000022374	ENSLBEP00000030990	Uncharacterized protein.	BCL2 associated X, apoptosis regulator a.	0.964
ENSLBEP00000022374	prkx	ENSLBEP00000022374	ENSLBEP00000022556	Uncharacterized protein.	Protein kinase X-linked; Belongs to the protein kinase superfamily.	0.476
ENSLBEP00000030423	tgfa	ENSLBEP00000030423	ENSLBEP00000001187	EGF-like domain-containing protein.	Transforming growth factor, alpha.	0.822
ENSLBEP00000031721	ENSLBEP00000031755	ENSLBEP00000031721	ENSLBEP00000031755	Lysyl oxidase-like 4.	Lysyl oxidase-like 4.	0.889
ENSLBEP00000031755	ENSLBEP00000031721	ENSLBEP00000031755	ENSLBEP00000031721	Lysyl oxidase-like 4.	Lysyl oxidase-like 4.	0.889
IGFBP3	LOC109990195	ENSLBEP00000022909	ENSLBEP00000018584	Insulin like growth factor binding protein 3.	Insulin-like growth factor binding protein 5a.	0.447
IGFBP3	igfbp5	ENSLBEP00000022909	ENSLBEP00000007182	Insulin like growth factor binding protein 3.	Insulin-like growth factor binding protein 5a.	0.447
LOC109975478	LOC110005100	ENSLBEP00000003931	ENSLBEP00000019350	Cytochrome P450, family 7, subfamily B, polypeptide 1.	Short chain dehydrogenase/reductase family 16C, member 5a; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.431
LOC109975478	sdr16c5	ENSLBEP00000003931	ENSLBEP00000018485	Cytochrome P450, family 7, subfamily B, polypeptide 1.	Short chain dehydrogenase/reductase family 16C, member 5a.	0.431
LOC109980354	LOC109991911	ENSLBEP00000013933	ENSLBEP00000016221	Uncharacterized protein; Belongs to the CD36 family.	Uncharacterized protein.	0.604
LOC109981070	ENSLBEP00000005272	ENSLBEP00000018998	ENSLBEP00000005272	Uncharacterized protein.	Uncharacterized protein.	0.852
LOC109981070	LOC109981436	ENSLBEP00000018998	ENSLBEP00000007964	Uncharacterized protein.	Uncharacterized protein.	0.835
LOC109981070	LOC110001654	ENSLBEP00000018998	ENSLBEP00000006731	Uncharacterized protein.	NK3 homeobox 1.	0.525
LOC109981070	prkx	ENSLBEP00000018998	ENSLBEP00000022556	Uncharacterized protein.	Protein kinase X-linked; Belongs to the protein kinase superfamily.	0.644