(41 nodes) Defense response to Gram-negative bacterium network (Labrus bergylta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC110000776	Uncharacterized protein. (140 aa)
	tusc2	Tumor suppressor 2, mitochondrial calcium regulator. (111 aa)
	rpl30	Ribosomal protein L30. (116 aa)
	ENSLBEP00000038523	MACPF domain-containing protein. (643 aa)
	ENSLBEP00000038813	Gla domain-containing protein. (95 aa)
	ENSLBEP00000038814	Kringle domain-containing protein. (142 aa)
	LOC110000783	Uncharacterized protein. (269 aa)
	ENSLBEP00000021486	CARD domain-containing protein. (103 aa)
	LOC109981531	TNFR-Cys domain-containing protein. (241 aa)
	LOC109981508	Uncharacterized protein. (280 aa)
	ENSLBEP00000022369	CARD domain-containing protein. (92 aa)
	LOC109978539	Uncharacterized protein. (208 aa)
	LOC109990321	Tumor suppressor 2, mitochondrial calcium regulator b. (111 aa)
	LOC109999589	Aquaporin 1a (Colton blood group), tandem duplicate 1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (261 aa)
	ENSLBEP00000026765	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (180 aa)
	LOC109999587	Aquaporin 1a (Colton blood group), tandem duplicate 2; Belongs to the MIP/aquaporin (TC 1.A.8) family. (264 aa)
	LOC109994830	Uncharacterized protein. (227 aa)
	LOC109982377	Uncharacterized protein. (166 aa)
	ENSLBEP00000029731	CARD domain-containing protein. (92 aa)
	IL12B	Interleukin 12B, b. (327 aa)
	ENSLBEP00000002674	CARD domain-containing protein. (93 aa)
	LOC109976797	TNFR-Cys domain-containing protein. (261 aa)
	LOC110004385	TNFR-Cys domain-containing protein. (165 aa)
	drosha	Drosha ribonuclease III. (1277 aa)
	MPEG1	Macrophage expressed 1. (708 aa)
	LOC109991209	MACPF domain-containing protein. (708 aa)
	ENSLBEP00000011198	Pyrin domain-containing protein. (191 aa)
	ENSLBEP00000012259	TNFR-Cys domain-containing protein. (265 aa)
	ENSLBEP00000012316	TNFR-Cys domain-containing protein. (296 aa)
	ENSLBEP00000012344	TNFR-Cys domain-containing protein. (265 aa)
	serpine1	Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; Belongs to the serpin family. (391 aa)
	LOC109983181	Uncharacterized protein. (475 aa)
	LOC109983171	Uncharacterized protein. (473 aa)
	ENSLBEP00000013847	CARD domain-containing protein. (99 aa)
	ENSLBEP00000014596	CARD domain-containing protein. (98 aa)
	ENSLBEP00000014843	MACPF domain-containing protein. (667 aa)
	ENSLBEP00000014967	MACPF domain-containing protein. (697 aa)
	f2	Coagulation factor II (thrombin); Belongs to the peptidase S1 family. (614 aa)
	LOC110004603	Uncharacterized protein. (300 aa)
	LOC110006283	TNFR-Cys domain-containing protein. (284 aa)
	LOC110004603-2	Uncharacterized protein. (288 aa)

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSLBEP00000038813	serpine1	ENSLBEP00000038813	ENSLBEP00000012870	Gla domain-containing protein.	Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; Belongs to the serpin family.	0.522
ENSLBEP00000038814	serpine1	ENSLBEP00000038814	ENSLBEP00000012870	Kringle domain-containing protein.	Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; Belongs to the serpin family.	0.522
LOC109982377	LOC110000776	ENSLBEP00000029235	ENSLBEP00000030419	Uncharacterized protein.	Uncharacterized protein.	0.915
LOC109982377	LOC110000783	ENSLBEP00000029235	ENSLBEP00000029119	Uncharacterized protein.	Uncharacterized protein.	0.848
LOC110000776	LOC109982377	ENSLBEP00000030419	ENSLBEP00000029235	Uncharacterized protein.	Uncharacterized protein.	0.915
LOC110000776	LOC110000783	ENSLBEP00000030419	ENSLBEP00000029119	Uncharacterized protein.	Uncharacterized protein.	0.906
LOC110000783	LOC109982377	ENSLBEP00000029119	ENSLBEP00000029235	Uncharacterized protein.	Uncharacterized protein.	0.848
LOC110000783	LOC110000776	ENSLBEP00000029119	ENSLBEP00000030419	Uncharacterized protein.	Uncharacterized protein.	0.906
f2	serpine1	ENSLBEP00000015302	ENSLBEP00000012870	Coagulation factor II (thrombin); Belongs to the peptidase S1 family.	Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; Belongs to the serpin family.	0.522
serpine1	ENSLBEP00000038813	ENSLBEP00000012870	ENSLBEP00000038813	Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; Belongs to the serpin family.	Gla domain-containing protein.	0.522
serpine1	ENSLBEP00000038814	ENSLBEP00000012870	ENSLBEP00000038814	Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; Belongs to the serpin family.	Kringle domain-containing protein.	0.522
serpine1	f2	ENSLBEP00000012870	ENSLBEP00000015302	Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; Belongs to the serpin family.	Coagulation factor II (thrombin); Belongs to the peptidase S1 family.	0.522