(101 nodes) Neuromuscular process network (Labrus bergylta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC109988624	Troponin I type 2b (skeletal, fast), tandem duplicate 1. (175 aa)
	LOC110001396	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family. (464 aa)
	mycbp2	MYC binding protein 2. (4537 aa)
	lrrc45	Leucine rich repeat containing 45. (675 aa)
	LOC109993337	GTP cyclohydrolase 2. (230 aa)
	stac	SH3 and cysteine rich domain. (446 aa)
	LOC109984503	Biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino. (220 aa)
	tmem150c	Transmembrane protein 150C. (246 aa)
	LOC110002040	Solute carrier family 17 member 8. (581 aa)
	LOC109981873	Uncharacterized protein. (1391 aa)
	LOC110001469	Uncharacterized protein. (458 aa)
	LOC110000726	GTP_cyclohydroI domain-containing protein. (227 aa)
	ENSLBEP00000000453	SH3 and multiple ankyrin repeat domains 3a. (1322 aa)
	LOC109976684	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (385 aa)
	LOC109975388	Dynactin domain-containing protein. (1142 aa)
	pou4f1	POU domain protein. (369 aa)
	LOC109989382	PNKD metallo-beta-lactamase domain containing. (359 aa)
	LOC109984778	CAP-ZIP_m domain-containing protein. (290 aa)
	gbx1	Gastrulation brain homeobox 1. (321 aa)
	shank2	SH3 and multiple ankyrin repeat domains 2a. (1805 aa)
	HOMER1	Homer scaffold protein 1. (356 aa)
	igdcc3	Immunoglobulin superfamily, DCC subclass, member 3. (653 aa)
	LOC109983540	CAP-ZIP_m domain-containing protein. (317 aa)
	LOC109982412	Uncharacterized protein. (598 aa)
	agtpbp1	ATP/GTP binding protein 1. (1088 aa)
	grin2a	Glutamate receptor, ionotropic, N-methyl D-aspartate 2A, a. (1433 aa)
	ENSLBEP00000003753	Uncharacterized protein. (481 aa)
	LOC109984777	Spartin b. (600 aa)
	slitrk6	SLIT and NTRK-like family, member 6. (843 aa)
	ush1c	Usher syndrome 1C. (680 aa)
	fxn	Frataxin. (210 aa)
	shank1	SH3 and multiple ankyrin repeat domains 1. (840 aa)
	ENSLBEP00000005147	Vesicle transport through interaction with t-SNAREs 1A. (175 aa)
	LOC109994116	Glutamate receptor, ionotropic, N-methyl D-aspartate 2Ca. (1391 aa)
	ENSLBEP00000005803	Si:ch73-71c20.5. (192 aa)
	LOC109984807	Troponin I type 2a (skeletal, fast), tandem duplicate 1. (161 aa)
	TNNI2	Uncharacterized protein. (171 aa)
	TNNI2-2	Uncharacterized protein. (166 aa)
	TNNI2-3	Uncharacterized protein. (171 aa)
	TNNI2-4	Troponin I2, fast skeletal type. (171 aa)
	STAC2	SH3 and cysteine rich domain 2. (424 aa)
	tcap	Titin-cap (telethonin). (180 aa)
	abl2	Tyrosine-protein kinase. (1213 aa)
	zmpste24	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (467 aa)
	ENSLBEP00000007781	Peptidase_M14 domain-containing protein. (205 aa)
	gm2a	GM2 ganglioside activator. (200 aa)
	LOC109987182	SH3 and cysteine rich domain 3. (248 aa)
	LOC109988253	Glutamate receptor, ionotropic, N-methyl D-aspartate 2A, b; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1342 aa)
	TNNC1	Troponin C type 1a (slow). (161 aa)
	LOC109990600	CAP-Gly domain-containing protein. (1296 aa)
	ENSLBEP00000010710	EF-hand domain-containing protein. (72 aa)
	LOC109984921	Troponin I type 1a (skeletal, slow). (186 aa)
	LOC110003797	Troponin I4b, tandem duplicate 2. (219 aa)
	ENSLBEP00000012270	Uncharacterized protein. (79 aa)
	LOC110003809	Troponin I4b, tandem duplicate 2. (192 aa)
	ENSLBEP00000012550	Troponin I4b, tandem duplicate 1. (175 aa)
	LOC109997571	SH3 and cysteine rich domain 2. (414 aa)
	ENSLBEP00000013419	Homeobox C10a. (315 aa)
	cln8	CLN8 transmembrane ER and ERGIC protein. (288 aa)
	ENSLBEP00000014776	Uncharacterized protein. (645 aa)
	synm	IF rod domain-containing protein; Belongs to the intermediate filament family. (327 aa)
	ENSLBEP00000014949	Uncharacterized protein. (181 aa)
	LOC109981544	Uncharacterized protein. (161 aa)
	mecp2	Methyl CpG binding protein 2. (1036 aa)
	get1	Guided entry of tail-anchored proteins factor 1. (170 aa)
	ENSLBEP00000016589	Uncharacterized protein. (184 aa)
	STAC3	SH3 and cysteine rich domain 3. (345 aa)
	r3hdm2	R3H domain containing 2. (1100 aa)
	OPA3	Outer mitochondrial membrane lipid metabolism regulator OPA3. (156 aa)
	LOC109983245	Otoferlin a. (2032 aa)
	mtor	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2492 aa)
	penk	Proenkephalin a. (247 aa)
	ENSLBEP00000018770	Coiled-coil domain containing 78. (441 aa)
	GLRB	Glycine receptor beta; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (496 aa)
	LOC109998752	Homer scaffold protein 1b. (363 aa)
	hexa	Beta-hexosaminidase. (502 aa)
	LOC109993686	Glutamate receptor, ionotropic, N-methyl D-aspartate 2D, b. (1831 aa)
	ucn	Urotensin 1. (121 aa)
	LOC109995485	Outer mitochondrial membrane lipid metabolism regulator OPA3. (156 aa)
	pou4f2	POU domain protein. (378 aa)
	ednra	Endothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family. (447 aa)
	drd3	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family. (454 aa)
	abl1	Tyrosine-protein kinase. (1132 aa)
	ENSLBEP00000026089	ANF_receptor domain-containing protein. (320 aa)
	LOC109982249	Protein tyrosine phosphatase receptor type Q. (2180 aa)
	hexb	Beta-hexosaminidase. (555 aa)
	LOC110002616	Dynactin 1b. (1337 aa)
	LOC109985070	Troponin C type 2 (fast). (160 aa)
	LOC109985113	Si:rp71-17i16.4. (161 aa)
	fer1l6	Fer-1 like family member 6. (1740 aa)
	GRIN3A	Glutamate ionotropic receptor NMDA type subunit 3A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1093 aa)
	LOC110002643	ATP/GTP binding protein-like 1. (960 aa)
	prkn	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (432 aa)
	ENSLBEP00000030320	Proline-rich transmembrane protein 2. (189 aa)
	LOC109988649	Uncharacterized protein. (627 aa)
	LOC109987561	Uncharacterized protein. (700 aa)
	xrcc1	X-ray repair complementing defective repair in Chinese hamster cells 1. (625 aa)
	LOC109981751	Troponin I type 1b (skeletal, slow). (196 aa)
	LOC109988647	GTP cyclohydrolase 1. (262 aa)
	ENSLBEP00000033183	Uncharacterized protein. (230 aa)
	APP	Amyloid beta precursor protein. (646 aa)

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APP	prkn	ENSLBEP00000033207	ENSLBEP00000029971	Amyloid beta precursor protein.	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	0.433
ENSLBEP00000000453	ENSLBEP00000033183	ENSLBEP00000000453	ENSLBEP00000033183	SH3 and multiple ankyrin repeat domains 3a.	Uncharacterized protein.	0.738
ENSLBEP00000000453	HOMER1	ENSLBEP00000000453	ENSLBEP00000002162	SH3 and multiple ankyrin repeat domains 3a.	Homer scaffold protein 1.	0.755
ENSLBEP00000000453	LOC109998752	ENSLBEP00000000453	ENSLBEP00000019729	SH3 and multiple ankyrin repeat domains 3a.	Homer scaffold protein 1b.	0.755
ENSLBEP00000000453	prkn	ENSLBEP00000000453	ENSLBEP00000029971	SH3 and multiple ankyrin repeat domains 3a.	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	0.530
ENSLBEP00000000453	shank1	ENSLBEP00000000453	ENSLBEP00000004795	SH3 and multiple ankyrin repeat domains 3a.	SH3 and multiple ankyrin repeat domains 1.	0.720
ENSLBEP00000000453	shank2	ENSLBEP00000000453	ENSLBEP00000002047	SH3 and multiple ankyrin repeat domains 3a.	SH3 and multiple ankyrin repeat domains 2a.	0.720
ENSLBEP00000005803	ENSLBEP00000030320	ENSLBEP00000005803	ENSLBEP00000030320	Si:ch73-71c20.5.	Proline-rich transmembrane protein 2.	0.503
ENSLBEP00000010710	ENSLBEP00000012270	ENSLBEP00000010710	ENSLBEP00000012270	EF-hand domain-containing protein.	Uncharacterized protein.	0.846
ENSLBEP00000010710	ENSLBEP00000012550	ENSLBEP00000010710	ENSLBEP00000012550	EF-hand domain-containing protein.	Troponin I4b, tandem duplicate 1.	0.846
ENSLBEP00000010710	LOC109981544	ENSLBEP00000010710	ENSLBEP00000015602	EF-hand domain-containing protein.	Uncharacterized protein.	0.762
ENSLBEP00000010710	LOC109981751	ENSLBEP00000010710	ENSLBEP00000032865	EF-hand domain-containing protein.	Troponin I type 1b (skeletal, slow).	0.888
ENSLBEP00000010710	LOC109984807	ENSLBEP00000010710	ENSLBEP00000005988	EF-hand domain-containing protein.	Troponin I type 2a (skeletal, fast), tandem duplicate 1.	0.955
ENSLBEP00000010710	LOC109984921	ENSLBEP00000010710	ENSLBEP00000011815	EF-hand domain-containing protein.	Troponin I type 1a (skeletal, slow).	0.888
ENSLBEP00000010710	LOC109988624	ENSLBEP00000010710	ENSLBEP00000033699	EF-hand domain-containing protein.	Troponin I type 2b (skeletal, fast), tandem duplicate 1.	0.961
ENSLBEP00000010710	LOC109997571	ENSLBEP00000010710	ENSLBEP00000013106	EF-hand domain-containing protein.	SH3 and cysteine rich domain 2.	0.406
ENSLBEP00000010710	LOC110003797	ENSLBEP00000010710	ENSLBEP00000012221	EF-hand domain-containing protein.	Troponin I4b, tandem duplicate 2.	0.846
ENSLBEP00000010710	LOC110003809	ENSLBEP00000010710	ENSLBEP00000012303	EF-hand domain-containing protein.	Troponin I4b, tandem duplicate 2.	0.846
ENSLBEP00000010710	STAC2	ENSLBEP00000010710	ENSLBEP00000006313	EF-hand domain-containing protein.	SH3 and cysteine rich domain 2.	0.406
ENSLBEP00000010710	TNNC1	ENSLBEP00000010710	ENSLBEP00000009716	EF-hand domain-containing protein.	Troponin C type 1a (slow).	0.762