(65 nodes) Regulation of DNA binding network (Labrus bergylta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSLBEP00000005796	Ring finger protein 220b. (243 aa)
	egf	Epidermal growth factor. (1031 aa)
	ski	V-ski avian sarcoma viral oncogene homolog a. (734 aa)
	ENSLBEP00000006290	PWWP domain-containing protein. (707 aa)
	ENSLBEP00000006346	Uncharacterized protein. (468 aa)
	LOC109999832	Info WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2a. (580 aa)
	taf10	TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (183 aa)
	zmpste24	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (467 aa)
	znf593	Zinc finger protein 593. (129 aa)
	gtf2b	General transcription factor IIB. (322 aa)
	ENSLBEP00000009221	Uncharacterized protein. (473 aa)
	LOC109989819	Uncharacterized protein. (448 aa)
	ENSLBEP00000010472	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (320 aa)
	LOC109992369	Grancalcin. (251 aa)
	nek2	NIMA-related kinase 2. (276 aa)
	LOC110004120	E1A binding protein p300 b. (2680 aa)
	rb1	Retinoblastoma 1. (899 aa)
	ZNF462	Zinc finger protein 462. (1284 aa)
	HAND1	Heart and neural crest derivatives expressed 1. (191 aa)
	ENSLBEP00000037308	SAP domain-containing protein. (856 aa)
	ep300	E1A binding protein p300 a. (2577 aa)
	ENSLBEP00000005779	RING-type domain-containing protein. (197 aa)
	LOC109975138	Chromatin licensing and DNA replication factor 1. (359 aa)
	ctnnbip1	Catenin, beta interacting protein 1. (81 aa)
	LOC109988511	JunE proto-oncogene, AP-1 transcription factor subunit. (344 aa)
	prkn	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (432 aa)
	ENSLBEP00000030281	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2b. (499 aa)
	LOC109991226	PHD-type domain-containing protein. (1409 aa)
	ENSLBEP00000012793	SAP domain-containing protein. (824 aa)
	LOC109980655	Uncharacterized protein. (112 aa)
	LOC109993896	Ankyrin repeat domain 33Bb. (482 aa)
	ercc4	Excision repair cross-complementation group 4. (895 aa)
	ercc2	Excision repair cross-complementation group 2. (760 aa)
	LOC109986693	Lymphocyte antigen 6 family member M6. (209 aa)
	LOC109979124	Helicase ATP-binding domain-containing protein. (628 aa)
	ENSLBEP00000014993	Uncharacterized protein. (99 aa)
	LOC109999402	Ring finger protein 220a. (566 aa)
	LOC109984218	MyoD family inhibitor. (304 aa)
	LOC109984878	Ankyrin repeat domain 33Aa. (431 aa)
	LOC109979211	Uncharacterized protein. (185 aa)
	ddit3	DNA-damage-inducible transcript 3. (311 aa)
	TFAP4	Transcription factor AP-4. (320 aa)
	smo	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (825 aa)
	LOC109983926	GATA binding protein 1a. (421 aa)
	LOC109995483	Transforming growth factor beta; Belongs to the TGF-beta family. (386 aa)
	sirt2	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (383 aa)
	LOC109993764	Ankyrin repeat domain 33. (457 aa)
	edf1	Endothelial differentiation-related factor 1. (157 aa)
	LOC109981634	Hyaluronan binding protein 4. (365 aa)
	dot1l	Histone-lysine N-methyltransferase, H3 lysine-79 specific. (1459 aa)
	tfap4	Transcription factor AP-4 (activating enhancer binding protein 4). (333 aa)
	sri	Uncharacterized protein. (179 aa)
	rsf1	Remodeling and spacing factor 1b, tandem duplicate 1. (1707 aa)
	LOC109985571	E2F transcription factor 1. (429 aa)
	LOC109983917	Inhibitor of DNA binding 1, HLH protein. (177 aa)
	ENSLBEP00000022272	TAZ-type domain-containing protein. (362 aa)
	LOC109990758	Muscle segment homeobox 3. (250 aa)
	LOC110000594	Ankyrin repeat domain 33ba. (526 aa)
	CDT1	Chromatin licensing and DNA replication factor 1. (683 aa)
	lef1	Lymphoid enhancer-binding factor 1. (379 aa)
	msx1	Muscle segment homeobox 1a. (278 aa)
	LOC109988736	Thioredoxin; Belongs to the thioredoxin family. (107 aa)
	LOC109988737	Thioredoxin domain-containing protein. (115 aa)
	pinx1	PIN2 (TERF1) interacting telomerase inhibitor 1. (396 aa)
	ENSLBEP00000002562	Uncharacterized protein. (99 aa)

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDT1	LOC109985571	ENSLBEP00000019127	ENSLBEP00000021656	Chromatin licensing and DNA replication factor 1.	E2F transcription factor 1.	0.486
CDT1	rb1	ENSLBEP00000019127	ENSLBEP00000035832	Chromatin licensing and DNA replication factor 1.	Retinoblastoma 1.	0.584
ENSLBEP00000002562	rb1	ENSLBEP00000002562	ENSLBEP00000035832	Uncharacterized protein.	Retinoblastoma 1.	0.475
ENSLBEP00000005779	ENSLBEP00000005796	ENSLBEP00000005779	ENSLBEP00000005796	RING-type domain-containing protein.	Ring finger protein 220b.	0.899
ENSLBEP00000005796	ENSLBEP00000005779	ENSLBEP00000005796	ENSLBEP00000005779	Ring finger protein 220b.	RING-type domain-containing protein.	0.899
ENSLBEP00000006290	ENSLBEP00000006346	ENSLBEP00000006290	ENSLBEP00000006346	PWWP domain-containing protein.	Uncharacterized protein.	0.800
ENSLBEP00000006290	ENSLBEP00000009221	ENSLBEP00000006290	ENSLBEP00000009221	PWWP domain-containing protein.	Uncharacterized protein.	0.778
ENSLBEP00000006290	ENSLBEP00000022272	ENSLBEP00000006290	ENSLBEP00000022272	PWWP domain-containing protein.	TAZ-type domain-containing protein.	0.523
ENSLBEP00000006290	LOC110004120	ENSLBEP00000006290	ENSLBEP00000035749	PWWP domain-containing protein.	E1A binding protein p300 b.	0.523
ENSLBEP00000006290	dot1l	ENSLBEP00000006290	ENSLBEP00000024159	PWWP domain-containing protein.	Histone-lysine N-methyltransferase, H3 lysine-79 specific.	0.854
ENSLBEP00000006290	ep300	ENSLBEP00000006290	ENSLBEP00000003268	PWWP domain-containing protein.	E1A binding protein p300 a.	0.523
ENSLBEP00000006290	sirt2	ENSLBEP00000006290	ENSLBEP00000023527	PWWP domain-containing protein.	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase.	0.409
ENSLBEP00000006346	ENSLBEP00000006290	ENSLBEP00000006346	ENSLBEP00000006290	Uncharacterized protein.	PWWP domain-containing protein.	0.800
ENSLBEP00000006346	ENSLBEP00000022272	ENSLBEP00000006346	ENSLBEP00000022272	Uncharacterized protein.	TAZ-type domain-containing protein.	0.523
ENSLBEP00000006346	LOC110004120	ENSLBEP00000006346	ENSLBEP00000035749	Uncharacterized protein.	E1A binding protein p300 b.	0.523
ENSLBEP00000006346	dot1l	ENSLBEP00000006346	ENSLBEP00000024159	Uncharacterized protein.	Histone-lysine N-methyltransferase, H3 lysine-79 specific.	0.854
ENSLBEP00000006346	ep300	ENSLBEP00000006346	ENSLBEP00000003268	Uncharacterized protein.	E1A binding protein p300 a.	0.523
ENSLBEP00000006346	sirt2	ENSLBEP00000006346	ENSLBEP00000023527	Uncharacterized protein.	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase.	0.409
ENSLBEP00000009221	ENSLBEP00000006290	ENSLBEP00000009221	ENSLBEP00000006290	Uncharacterized protein.	PWWP domain-containing protein.	0.778
ENSLBEP00000009221	ENSLBEP00000022272	ENSLBEP00000009221	ENSLBEP00000022272	Uncharacterized protein.	TAZ-type domain-containing protein.	0.523