(51 nodes) Release of sequestered calcium ion into cytosol network (Labrus bergylta)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	SLC8B1	Solute carrier family 8 member B1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (586 aa)
	ibtk	Inhibitor of Bruton agammaglobulinemia tyrosine kinase. (1343 aa)
	ENSLBEP00000005858	Uncharacterized protein. (1010 aa)
	ENSLBEP00000006079	Uncharacterized protein. (304 aa)
	letm1	Leucine zipper-EF-hand containing transmembrane protein 1. (679 aa)
	ENSLBEP00000007700	PKD_channel domain-containing protein. (363 aa)
	LOC109998011	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (371 aa)
	letm2	Leucine zipper-EF-hand containing transmembrane protein 2. (517 aa)
	LOC109985057	Chemokine (C motif) receptor 1b, duplicate 1; Belongs to the G-protein coupled receptor 1 family. (351 aa)
	pkd2	Polycystic kidney disease 2. (903 aa)
	LOC110003801	Inositol 1,4,5-trisphosphate receptor, type 2. (2003 aa)
	LOC109989114	SCY domain-containing protein. (112 aa)
	LOC109984974	Mucolipin 3a. (549 aa)
	LOC109995464	Ryanodine receptor 1b (skeletal). (4954 aa)
	itpr1	Inositol 1,4,5-trisphosphate receptor, type 1a. (2706 aa)
	ENSLBEP00000024500	annotation not available (146 aa)
	LOC109983881	Inositol 1,4,5-trisphosphate receptor, type 1b. (2690 aa)
	LOC109987903	Ryanodine receptor 2b (cardiac). (3910 aa)
	htr2a	5-hydroxytryptamine (serotonin) receptor 2A, genome duplicate a. (519 aa)
	LOC109995581	5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled-like 1. (581 aa)
	bax	BCL2 associated X, apoptosis regulator a. (192 aa)
	ENSLBEP00000031813	Ins145_P3_rec domain-containing protein. (164 aa)
	ENSLBEP00000031942	Uncharacterized protein. (631 aa)
	LOC110002727	Uncharacterized protein. (668 aa)
	htr2b	5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled. (473 aa)
	gp1bb	Glycoprotein Ib platelet subunit beta. (204 aa)
	LOC110001377	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (378 aa)
	RYR3	Ryanodine receptor 3. (4726 aa)
	mcoln1	Mucolipin 1b. (563 aa)
	mcoln2	Mucolipin 2. (563 aa)
	ptprc	Protein tyrosine phosphatase receptor type C. (1151 aa)
	ENSLBEP00000037504	LRRCT domain-containing protein. (361 aa)
	RYR2	Uncharacterized protein. (4797 aa)
	LOC109999151	Si:ch211-237i5.4. (345 aa)
	LOC109981009	Glycoprotein IX (platelet). (235 aa)
	LOC110002853	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (574 aa)
	cherp	Calcium homeostasis endoplasmic reticulum protein. (775 aa)
	LOC109982580	Fas ligand (TNF superfamily, member 6); Belongs to the tumor necrosis factor family. (266 aa)
	ENSLBEP00000012830	Ins145_P3_rec domain-containing protein. (125 aa)
	LOC110003734	Two pore segment channel 3. (793 aa)
	ENSLBEP00000038186	Ion_trans domain-containing protein. (469 aa)
	trpa1	Transient receptor potential cation channel, subfamily A, member 1b; Belongs to the transient receptor (TC 1.A.4) family. (1119 aa)
	ryr3	Ryanodine receptor 3. (4267 aa)
	ENSLBEP00000018645	Ins145_P3_rec domain-containing protein. (129 aa)
	TPCN2	Uncharacterized protein. (809 aa)
	ENSLBEP00000013648	Ins145_P3_rec domain-containing protein. (146 aa)
	LOC110004577	Inositol 1,4,5-trisphosphate receptor, type 3. (1352 aa)
	ddit3	DNA-damage-inducible transcript 3. (311 aa)
	LOC109998140	C-C motif chemokine. (91 aa)
	MCOLN3	Mucolipin 3. (549 aa)
	tpcn1	Two pore segment channel 1. (820 aa)

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSLBEP00000005858	ENSLBEP00000038186	ENSLBEP00000005858	ENSLBEP00000038186	Uncharacterized protein.	Ion_trans domain-containing protein.	0.888
ENSLBEP00000006079	ENSLBEP00000007700	ENSLBEP00000006079	ENSLBEP00000007700	Uncharacterized protein.	PKD_channel domain-containing protein.	0.536
ENSLBEP00000006079	trpa1	ENSLBEP00000006079	ENSLBEP00000019399	Uncharacterized protein.	Transient receptor potential cation channel, subfamily A, member 1b; Belongs to the transient receptor (TC 1.A.4) family.	0.533
ENSLBEP00000007700	ENSLBEP00000006079	ENSLBEP00000007700	ENSLBEP00000006079	PKD_channel domain-containing protein.	Uncharacterized protein.	0.536
ENSLBEP00000007700	LOC109984974	ENSLBEP00000007700	ENSLBEP00000022175	PKD_channel domain-containing protein.	Mucolipin 3a.	0.666
ENSLBEP00000007700	MCOLN3	ENSLBEP00000007700	ENSLBEP00000017567	PKD_channel domain-containing protein.	Mucolipin 3.	0.670
ENSLBEP00000007700	mcoln2	ENSLBEP00000007700	ENSLBEP00000036154	PKD_channel domain-containing protein.	Mucolipin 2.	0.824
ENSLBEP00000007700	trpa1	ENSLBEP00000007700	ENSLBEP00000019399	PKD_channel domain-containing protein.	Transient receptor potential cation channel, subfamily A, member 1b; Belongs to the transient receptor (TC 1.A.4) family.	0.533
ENSLBEP00000012830	LOC109987903	ENSLBEP00000012830	ENSLBEP00000025897	Ins145_P3_rec domain-containing protein.	Ryanodine receptor 2b (cardiac).	0.591
ENSLBEP00000012830	ryr3	ENSLBEP00000012830	ENSLBEP00000018746	Ins145_P3_rec domain-containing protein.	Ryanodine receptor 3.	0.648
ENSLBEP00000013648	LOC110003734	ENSLBEP00000013648	ENSLBEP00000013267	Ins145_P3_rec domain-containing protein.	Two pore segment channel 3.	0.523
ENSLBEP00000013648	tpcn1	ENSLBEP00000013648	ENSLBEP00000017557	Ins145_P3_rec domain-containing protein.	Two pore segment channel 1.	0.523
ENSLBEP00000024500	LOC110003734	ENSLBEP00000024500	ENSLBEP00000013267	annotation not available	Two pore segment channel 3.	0.523
ENSLBEP00000024500	tpcn1	ENSLBEP00000024500	ENSLBEP00000017557	annotation not available	Two pore segment channel 1.	0.523
ENSLBEP00000031813	ENSLBEP00000031942	ENSLBEP00000031813	ENSLBEP00000031942	Ins145_P3_rec domain-containing protein.	Uncharacterized protein.	0.934
ENSLBEP00000031813	ENSLBEP00000038186	ENSLBEP00000031813	ENSLBEP00000038186	Ins145_P3_rec domain-containing protein.	Ion_trans domain-containing protein.	0.918
ENSLBEP00000031813	LOC110003801	ENSLBEP00000031813	ENSLBEP00000021639	Ins145_P3_rec domain-containing protein.	Inositol 1,4,5-trisphosphate receptor, type 2.	0.822
ENSLBEP00000031813	LOC110004577	ENSLBEP00000031813	ENSLBEP00000016062	Ins145_P3_rec domain-containing protein.	Inositol 1,4,5-trisphosphate receptor, type 3.	0.930
ENSLBEP00000031942	ENSLBEP00000031813	ENSLBEP00000031942	ENSLBEP00000031813	Uncharacterized protein.	Ins145_P3_rec domain-containing protein.	0.934
ENSLBEP00000031942	ENSLBEP00000038186	ENSLBEP00000031942	ENSLBEP00000038186	Uncharacterized protein.	Ion_trans domain-containing protein.	0.941