(22 nodes) Regulation of cardiac muscle contraction network (Labrus bergylta)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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Others

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co-expression

protein homology

Your Input:
	nkx2-5	NK2 homeobox 5. (315 aa)
	LOC109990924	Potassium voltage-gated channel, KQT-like subfamily, member 1.1; Belongs to the potassium channel family. (586 aa)
	rnf207	Uncharacterized protein. (582 aa)
	LOC109999113	Zinc finger CCCH-type containing 12A. (627 aa)
	gja5	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (380 aa)
	LOC110005611	Uncharacterized protein; Belongs to the potassium channel family. (724 aa)
	ankrd44	Ankyrin repeat domain 44. (919 aa)
	zc3h12a	Si:dkey-206d17.12. (590 aa)
	ucn	Urotensin 1. (121 aa)
	pkd2	Polycystic kidney disease 2. (903 aa)
	cav3	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (152 aa)
	LOC109990113	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (154 aa)
	pln	Si:ch211-270g19.5. (53 aa)
	ENSLBEP00000013073	Ring finger protein 207a. (169 aa)
	LOC109992369	Grancalcin. (251 aa)
	LOC109990637	Junction plakoglobin a. (705 aa)
	ankrd28	Ankyrin repeat domain 28b. (1052 aa)
	LOC109977742	Ankyrin repeat domain 66. (168 aa)
	LOC109995768	Uncharacterized protein. (748 aa)
	LOC109992872	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (412 aa)
	LOC109982406	ANK_REP_REGION domain-containing protein. (1068 aa)
	sri	Uncharacterized protein. (179 aa)

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC109990113	LOC109990637	ENSLBEP00000015571	ENSLBEP00000011430	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Junction plakoglobin a.	0.652
LOC109990113	LOC109995768	ENSLBEP00000015571	ENSLBEP00000004708	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Uncharacterized protein.	0.652
LOC109990113	cav3	ENSLBEP00000015571	ENSLBEP00000015590	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.937
LOC109990637	LOC109990113	ENSLBEP00000011430	ENSLBEP00000015571	Junction plakoglobin a.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.652
LOC109990637	cav3	ENSLBEP00000011430	ENSLBEP00000015590	Junction plakoglobin a.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.595
LOC109990924	LOC110005611	ENSLBEP00000034682	ENSLBEP00000029888	Potassium voltage-gated channel, KQT-like subfamily, member 1.1; Belongs to the potassium channel family.	Uncharacterized protein; Belongs to the potassium channel family.	0.845
LOC109992872	nkx2-5	ENSLBEP00000003234	ENSLBEP00000030128	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	NK2 homeobox 5.	0.424
LOC109995768	LOC109990113	ENSLBEP00000004708	ENSLBEP00000015571	Uncharacterized protein.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.652
LOC109995768	cav3	ENSLBEP00000004708	ENSLBEP00000015590	Uncharacterized protein.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.595
LOC110005611	LOC109990924	ENSLBEP00000029888	ENSLBEP00000034682	Uncharacterized protein; Belongs to the potassium channel family.	Potassium voltage-gated channel, KQT-like subfamily, member 1.1; Belongs to the potassium channel family.	0.845
cav3	LOC109990113	ENSLBEP00000015590	ENSLBEP00000015571	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.937
cav3	LOC109990637	ENSLBEP00000015590	ENSLBEP00000011430	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Junction plakoglobin a.	0.595
cav3	LOC109995768	ENSLBEP00000015590	ENSLBEP00000004708	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Uncharacterized protein.	0.595
gja5	nkx2-5	ENSLBEP00000037431	ENSLBEP00000030128	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	NK2 homeobox 5.	0.424
nkx2-5	LOC109992872	ENSLBEP00000030128	ENSLBEP00000003234	NK2 homeobox 5.	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	0.424
nkx2-5	gja5	ENSLBEP00000030128	ENSLBEP00000037431	NK2 homeobox 5.	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	0.424