(47 nodes) Bone morphogenesis network (Labrus bergylta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSLBEP00000014606	Serpin peptidase inhibitor, clade H (heat shock protein 47), member 1a; Belongs to the serpin family. (201 aa)
	msx1	Muscle segment homeobox 1a. (278 aa)
	ext2	Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family. (719 aa)
	ENSLBEP00000001446	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (203 aa)
	ENSLBEP00000001462	CNX domain-containing protein. (142 aa)
	ENSLBEP00000001811	Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family. (208 aa)
	edar	Ectodysplasin A receptor. (510 aa)
	LOC109999233	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (792 aa)
	GJA1	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (388 aa)
	LOC110005565	Uncharacterized protein. (493 aa)
	kat2a	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (797 aa)
	LOC109984812	Golgi glycoprotein 1a. (1168 aa)
	foxn3	Checkpoint suppressor 1. (485 aa)
	zmpste24	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (467 aa)
	smpd3	Sphingomyelin phosphodiesterase 3, neutral. (725 aa)
	LOC109999905	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa)
	bmpr2	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1041 aa)
	ENSLBEP00000014589	Serpin peptidase inhibitor, clade H (heat shock protein 47), member 1a; Belongs to the serpin family. (160 aa)
	LOC109986206	RAP1A, member of RAS oncogene family b. (185 aa)
	rab23	RAB23, member RAS oncogene family. (235 aa)
	LOC109991328	Fras1 related extracellular matrix 1a. (1970 aa)
	trip11	Thyroid hormone receptor interactor 11. (1824 aa)
	LOC109985667	Uncharacterized protein. (185 aa)
	LOC109998011	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (371 aa)
	ENSLBEP00000019863	Uncharacterized protein. (144 aa)
	ENSLBEP00000022073	Uncharacterized protein. (225 aa)
	ENSLBEP00000022422	Uncharacterized protein. (189 aa)
	sp5	Sp5 transcription factor a. (376 aa)
	tsku	Tsukushi small leucine rich proteoglycan homolog (Xenopus laevis). (348 aa)
	LOC109992067	Serpin peptidase inhibitor, clade H (heat shock protein 47), member 1b; Belongs to the serpin family. (405 aa)
	atg9a	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (822 aa)
	LOC110001878	Cytochrome P450, family 26, subfamily b, polypeptide 1; Belongs to the cytochrome P450 family. (512 aa)
	LOC109982371	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (229 aa)
	LOC109985155	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
	ENSLBEP00000029576	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (343 aa)
	nab2	NGFI-A binding protein 2 (EGR1 binding protein 2). (493 aa)
	ift80	Intraflagellar transport 80 homolog (Chlamydomonas). (775 aa)
	LOC110000840	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (485 aa)
	ENSLBEP00000032575	MADS-box domain-containing protein. (159 aa)
	LOC109996736	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (188 aa)
	LOC109985163	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (992 aa)
	LOC109988623	Golgi glycoprotein 1b. (1162 aa)
	LOC110001377	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (378 aa)
	MEF2D	MADS-box domain-containing protein. (592 aa)
	dhrs3	Dehydrogenase/reductase (SDR family) member 3b; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (302 aa)
	TGFBR2	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (555 aa)
	anxa6	Annexin. (656 aa)

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSLBEP00000001446	ENSLBEP00000001462	ENSLBEP00000001446	ENSLBEP00000001462	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	CNX domain-containing protein.	0.559
ENSLBEP00000001462	ENSLBEP00000001446	ENSLBEP00000001462	ENSLBEP00000001446	CNX domain-containing protein.	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	0.559
ENSLBEP00000001462	ENSLBEP00000029576	ENSLBEP00000001462	ENSLBEP00000029576	CNX domain-containing protein.	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	0.594
ENSLBEP00000001811	LOC109982371	ENSLBEP00000001811	ENSLBEP00000026874	Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.528
ENSLBEP00000001811	LOC109985155	ENSLBEP00000001811	ENSLBEP00000028869	Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.528
ENSLBEP00000001811	LOC109996736	ENSLBEP00000001811	ENSLBEP00000032847	Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.528
ENSLBEP00000014589	ENSLBEP00000014606	ENSLBEP00000014589	ENSLBEP00000014606	Serpin peptidase inhibitor, clade H (heat shock protein 47), member 1a; Belongs to the serpin family.	Serpin peptidase inhibitor, clade H (heat shock protein 47), member 1a; Belongs to the serpin family.	0.907
ENSLBEP00000014606	ENSLBEP00000014589	ENSLBEP00000014606	ENSLBEP00000014589	Serpin peptidase inhibitor, clade H (heat shock protein 47), member 1a; Belongs to the serpin family.	Serpin peptidase inhibitor, clade H (heat shock protein 47), member 1a; Belongs to the serpin family.	0.907
ENSLBEP00000029576	ENSLBEP00000001462	ENSLBEP00000029576	ENSLBEP00000001462	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	CNX domain-containing protein.	0.594
LOC109982371	ENSLBEP00000001811	ENSLBEP00000026874	ENSLBEP00000001811	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family.	0.528
LOC109982371	LOC109999905	ENSLBEP00000026874	ENSLBEP00000009403	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.528
LOC109985155	ENSLBEP00000001811	ENSLBEP00000028869	ENSLBEP00000001811	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family.	0.528
LOC109985155	LOC109999905	ENSLBEP00000028869	ENSLBEP00000009403	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.528
LOC109996736	ENSLBEP00000001811	ENSLBEP00000032847	ENSLBEP00000001811	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family.	0.528
LOC109996736	LOC109999905	ENSLBEP00000032847	ENSLBEP00000009403	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.528
LOC109999233	foxn3	ENSLBEP00000003190	ENSLBEP00000007220	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily.	Checkpoint suppressor 1.	0.445
LOC109999233	ift80	ENSLBEP00000003190	ENSLBEP00000030045	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily.	Intraflagellar transport 80 homolog (Chlamydomonas).	0.606
LOC109999233	kat2a	ENSLBEP00000003190	ENSLBEP00000005448	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily.	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily.	0.841
LOC109999905	LOC109982371	ENSLBEP00000009403	ENSLBEP00000026874	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.528
LOC109999905	LOC109985155	ENSLBEP00000009403	ENSLBEP00000028869	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.528