(22 nodes) Lung morphogenesis network (Labrus bergylta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TGFBR2	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (555 aa)
	wnt2b	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (391 aa)
	stk40	Serine/threonine kinase 40. (436 aa)
	CTSH	Cathepsin H; Belongs to the peptidase C1 family. (238 aa)
	ENSLBEP00000004175	Sprouty RTK signaling antagonist 2. (376 aa)
	lama1	Laminin, alpha 1. (2848 aa)
	tcf21	Transcription factor 21. (170 aa)
	dlg5	Discs, large homolog 5a (Drosophila); Belongs to the MAGUK family. (1858 aa)
	LOC109980963	Peptidase S72 domain-containing protein. (910 aa)
	srf	Serum response factor b. (526 aa)
	LOC110004065	Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (301 aa)
	ENSLBEP00000020769	Peptidase S72 domain-containing protein. (893 aa)
	LOC109998247	Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (299 aa)
	hps1	HPS1 biogenesis of lysosomal organelles complex 3 subunit 1. (637 aa)
	LOC110000840	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (485 aa)
	LOC109997239	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (390 aa)
	ctsz	Cathepsin Z; Belongs to the peptidase C1 family. (303 aa)
	LOC109982254	Cathepsin H; Belongs to the peptidase C1 family. (305 aa)
	ENSLBEP00000024592	Inhibitor_I29 domain-containing protein. (125 aa)
	LOC110003829	Dystroglycan 1. (890 aa)
	hhip	Hedgehog interacting protein. (697 aa)
	SRF	Serum response factor. (278 aa)

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CTSH	LOC109998247	ENSLBEP00000008998	ENSLBEP00000021508	Cathepsin H; Belongs to the peptidase C1 family.	Pept_C1 domain-containing protein; Belongs to the peptidase C1 family.	0.655
CTSH	LOC110004065	ENSLBEP00000008998	ENSLBEP00000017479	Cathepsin H; Belongs to the peptidase C1 family.	Pept_C1 domain-containing protein; Belongs to the peptidase C1 family.	0.655
CTSH	ctsz	ENSLBEP00000008998	ENSLBEP00000030268	Cathepsin H; Belongs to the peptidase C1 family.	Cathepsin Z; Belongs to the peptidase C1 family.	0.655
ENSLBEP00000020769	LOC109980963	ENSLBEP00000020769	ENSLBEP00000014650	Peptidase S72 domain-containing protein.	Peptidase S72 domain-containing protein.	0.891
ENSLBEP00000020769	lama1	ENSLBEP00000020769	ENSLBEP00000003930	Peptidase S72 domain-containing protein.	Laminin, alpha 1.	0.862
ENSLBEP00000024592	LOC109998247	ENSLBEP00000024592	ENSLBEP00000021508	Inhibitor_I29 domain-containing protein.	Pept_C1 domain-containing protein; Belongs to the peptidase C1 family.	0.655
ENSLBEP00000024592	LOC110004065	ENSLBEP00000024592	ENSLBEP00000017479	Inhibitor_I29 domain-containing protein.	Pept_C1 domain-containing protein; Belongs to the peptidase C1 family.	0.655
ENSLBEP00000024592	ctsz	ENSLBEP00000024592	ENSLBEP00000030268	Inhibitor_I29 domain-containing protein.	Cathepsin Z; Belongs to the peptidase C1 family.	0.655
LOC109980963	ENSLBEP00000020769	ENSLBEP00000014650	ENSLBEP00000020769	Peptidase S72 domain-containing protein.	Peptidase S72 domain-containing protein.	0.891
LOC109980963	LOC110003829	ENSLBEP00000014650	ENSLBEP00000022470	Peptidase S72 domain-containing protein.	Dystroglycan 1.	0.889
LOC109980963	lama1	ENSLBEP00000014650	ENSLBEP00000003930	Peptidase S72 domain-containing protein.	Laminin, alpha 1.	0.862
LOC109982254	LOC109998247	ENSLBEP00000024653	ENSLBEP00000021508	Cathepsin H; Belongs to the peptidase C1 family.	Pept_C1 domain-containing protein; Belongs to the peptidase C1 family.	0.655
LOC109982254	LOC110004065	ENSLBEP00000024653	ENSLBEP00000017479	Cathepsin H; Belongs to the peptidase C1 family.	Pept_C1 domain-containing protein; Belongs to the peptidase C1 family.	0.655
LOC109982254	ctsz	ENSLBEP00000024653	ENSLBEP00000030268	Cathepsin H; Belongs to the peptidase C1 family.	Cathepsin Z; Belongs to the peptidase C1 family.	0.655
LOC109998247	CTSH	ENSLBEP00000021508	ENSLBEP00000008998	Pept_C1 domain-containing protein; Belongs to the peptidase C1 family.	Cathepsin H; Belongs to the peptidase C1 family.	0.655
LOC109998247	ENSLBEP00000024592	ENSLBEP00000021508	ENSLBEP00000024592	Pept_C1 domain-containing protein; Belongs to the peptidase C1 family.	Inhibitor_I29 domain-containing protein.	0.655
LOC109998247	LOC109982254	ENSLBEP00000021508	ENSLBEP00000024653	Pept_C1 domain-containing protein; Belongs to the peptidase C1 family.	Cathepsin H; Belongs to the peptidase C1 family.	0.655
LOC110000840	TGFBR2	ENSLBEP00000032116	ENSLBEP00000036684	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.842
LOC110003829	LOC109980963	ENSLBEP00000022470	ENSLBEP00000014650	Dystroglycan 1.	Peptidase S72 domain-containing protein.	0.889
LOC110003829	lama1	ENSLBEP00000022470	ENSLBEP00000003930	Dystroglycan 1.	Laminin, alpha 1.	0.862